Skip to main content

News

Where hypotheses become headlines: Featured coverage of the breakthroughs—and the people—driving our research forward

For media inquiries, email us: [email protected]


Featured News
Chi-Huey Wong.
News

Scripps Research professor Chi-Huey Wong to receive ACS Alfred Bader Award

Dissociation of the four-part TTR protein. The energy landscape shows stable states toward the bottom and unstable transition states toward the top. In the canonical pathway (red), the tetramer (T) dissociates via a native-like, compact transition state (‡1) into transient dimer intermediates (D) before full dissociation into monomers (M). In the newly discovered alternative pathway (blue), the tetramer dissociates through a more expanded transition state (‡2) directly into monomers. Credit: Jan-Hannes Schäfer, Scripps Research
News

Scientists discover a new way that a disease-linked protein comes apart

Filter by:
  • Chemists snap together complex 3D molecules from highly reactive ‘radicals’—without losing their shape
    News

    Chemists snap together complex 3D molecules from highly reactive ‘radicals’—without losing their shape

    Scripps Research team develops stereoretentive radical-radical cross-coupling, a simpler way to build chiral drug candidates.

  • Calibr-Skaggs advances CLF065, a regenerative GLP-2 therapy, into two Phase 2 IBD studies
    News

    Calibr-Skaggs advances CLF065, a regenerative GLP-2 therapy, into two Phase 2 IBD studies

    CLF065, a long-acting, once-weekly GLP-2 receptor agonist, advances in two inflammatory bowel disease indications. The studies aim to bring a regenerative treatment option to patients living with IBD, who currently have few therapies that repair the damaged intestinal lining at the root of their disease.

  • Experimental HIV vaccine achieves a long-sought goal
    News

    Experimental HIV vaccine achieves a long-sought goal

    In a first for the field, all non-human primates given a new series of vaccines generated antibodies capable of fighting multiple strains of HIV.

  • Scripps Research chemist Jin-Quan Yu is named a Fellow of the Royal Society
    News

    Scripps Research chemist Jin-Quan Yu is named a Fellow of the Royal Society

    Yu is honored by the U.K.’s national academy of sciences for his work in synthetic organic chemistry.

    Chemistry Jian-Quan Yu
  • Scripps Research’s Skaggs Graduate School awards doctoral degrees to 34th graduating class
    News

    Scripps Research’s Skaggs Graduate School awards doctoral degrees to 34th graduating class

  • Scripps Research establishes endowed chair honoring renowned structural biologist Ian Wilson
    News

    Scripps Research establishes endowed chair honoring renowned structural biologist Ian Wilson

    Keren Lasker to be inaugural chair holder

  • How changes to proteins can alter drug interactions for new precision therapies
    News

    How changes to proteins can alter drug interactions for new precision therapies

    Scripps Research team maps how chemical modifications to proteins affect drug binding across the human proteome.

  • Scripps Research immunologist Dennis Burton elected to American Academy of Arts and Sciences
    News

    Scripps Research immunologist Dennis Burton elected to American Academy of Arts and Sciences

    A leader in broadly neutralizing antibodies, Burton has helped drive global efforts to develop vaccines for HIV, influenza and more.

  • Scripps Research chemist Benjamin Cravatt elected to American Philosophical Society
    News

    Scripps Research chemist Benjamin Cravatt elected to American Philosophical Society

  • Scripps Research ranks third in 2026 Cure Innovation Index
    News

    Scripps Research ranks third in 2026 Cure Innovation Index

  • Jin-Quan Yu elected to the National Academy of Sciences
    News

    Jin-Quan Yu elected to the National Academy of Sciences

    Yu is recognized for his pioneering work in synthetic organic chemistry.

  • How a chemical reaction triggers brain inflammation in Alzheimer’s disease
    News

    How a chemical reaction triggers brain inflammation in Alzheimer’s disease

    Scripps Research scientists discovered that a chemically modified protein puts the brain’s immune cells in a state of damaging, chronic overactivation—and that blocking it protects brain cell connections.

  • Improving vaccine design for Ebola, HIV and more
    News

    Improving vaccine design for Ebola, HIV and more

    Scripps Research scientists and colleagues develop a nanodisc platform that offers a clearer view of how key viral proteins interact with antibodies.

  • NIH expected to award Scripps Research nearly $4.2 million over 5 years to advance tools for vaccine design
    News

    NIH expected to award Scripps Research nearly $4.2 million over 5 years to advance tools for vaccine design

    Funding will expand methods for studying viral proteins and immune responses in more realistic settings for HIV and other severe pathogens.

  • New technique for synthesizing branched molecules could accelerate the development of future medicines
    News

    New technique for synthesizing branched molecules could accelerate the development of future medicines

    Scripps Research chemists solve a longstanding problem in the construction of branched molecular frameworks, unlocking a faster path to the complex structures found in drugs and materials.

  • Scripps Research’s Skaggs Graduate School ranked #1 in Biological Sciences by U.S. News & World Report
    News

    Scripps Research’s Skaggs Graduate School ranked #1 in Biological Sciences by U.S. News & World Report

    The doctoral program also placed #7 in Chemistry in the publication’s latest issue ranking top science graduate schools.

  • Scripps Research scientists uncover new mechanism cancer cells use to survive DNA damage
    News

    Scripps Research scientists uncover new mechanism cancer cells use to survive DNA damage

    Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

  • Study shows new drug compounds dial down inflammation without compromising immunity
    News

    Study shows new drug compounds dial down inflammation without compromising immunity

    First-in-class molecules block a specific protein interaction in immune cells, offering a potential targeted approach to autoimmune diseases like lupus and rheumatoid arthritis.

  • Scripps Research scientists awarded nearly $5 million by NIH to investigate cancer growth
    News

    Scripps Research scientists awarded nearly $5 million by NIH to investigate cancer growth

    Researchers will investigate how a common dietary nutrient may control a hidden layer of gene regulation in cancer cells.

  • Scientists pinpoint protein shapes that track Alzheimer’s progression
    News

    Scientists pinpoint protein shapes that track Alzheimer’s progression

    New findings from Scripps Research show that changes in protein shape—rather than quantity of proteins—offer a potential new way to detect and track Alzheimer’s disease.

  • A new clue to how the body detects physical force
    News

    A new clue to how the body detects physical force

    Scripps Research scientists offer new insight into how the body detects light touch and how disruptions in that process may contribute to sensory disorders.

  • Nanoparticle vaccine approach takes on a new target: Hepatitis C virus
    News

    Nanoparticle vaccine approach takes on a new target: Hepatitis C virus

    Scripps Research scientists reengineer critical proteins on the surface of HCV, paving the way for a new vaccine design.

  • Scripps Research welcomes healthcare innovator Joe Kiani to the Board of Directors
    News

    Scripps Research welcomes healthcare innovator Joe Kiani to the Board of Directors

    Kiani brings decades of experience in patient safety and public service.

  • New way to intentionally discover molecular glues could expand drug discovery
    News

    New way to intentionally discover molecular glues could expand drug discovery

    Scripps Research scientists and colleagues show how drugs that eliminate certain disease-driving proteins can be discovered systematically rather than by chance.

Groundbreaking Science.
Life-changing Medicine.