News

Innovative cellular therapy has potential to treat patients with lupus, systemic sclerosis, myositis and RA without chemotherapy-induced immune suppression.

Scripps Research and aTyr Pharma scientists have revealed how the protein HARSWHEP calms inflammation associated with sarcoidosis.

Scripps Research scientists reveal that microRNAs guide the development of Purkinje cells, a rare type of neuron linked to neurodevelopmental disorders.

Researchers reprogrammed a botulinum toxin protease to selectively break down disease-causing proteins in human cells, providing proof of concept for developing new therapies for a wide range of illnesses.

Scripps Research chemistry professor Chi-Huey Wong presents results from his team’s studies at the ACS Spring 2025 Digital Meeting.

New structural hallmarks of memory storage discovered by Scripps Research could lead to treatments for memory loss.

Scripps Research scientists created a stable form of carnosic acid, observing greater memory function and other disease improvements in mice.

New structural blueprint is key for better targeting cancer cells, particularly those with BRCA1 and 2 mutations.

Scripps Research scientists discovered how a chemical modification of a key brain protein—potentially triggered by climate change-induced air pollution, pesticides, wildfires and processed meats—disrupts normal brain cell function.

ADA’s $1.3 million grant will support the Droujinine lab’s research of interorgan dialogue to develop therapeutics for diabetes management.

Scripps Research announces its 2024 recipients of Collaborative Innovation Fund grants.

Insights could advance new drugs to treat the progressive, fatal disease known as transthyretin amyloidosis.

Calibr-Skaggs’ long-acting injectable (LAI) platform transforms oral malaria treatment atovaquone, aiming for protection from malaria for three months.

Scripps Research scientists discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.

New findings reveal a technique to transform essential chemical building blocks for drug discovery and beyond—representing the “final step” in applying this method to all key classes of organic molecules.

By using computer modeling to predict chemical reactions, Scripps Research scientists were able to synthesize 25 variations of a plant compound that could treat brain diseases.

A new study uncovers how DNA, magnesium and polyphosphate form a balance that’s just right—which could lead to innovations in medicine and biotechnology.

Scripps Research scientists reveal microgravity’s effects on brain cells.

The National Institutes for Health’s (NIH) HEAL Initiative has awarded Alejandra Mendoza, PhD, assistant professor of Immunology and Microbiology, more than $1.6 million as part of a DP2 grant designed to support early-stage investigators with highly innovative and impactful research.

A new, more sustainable AI model recognizes visual scenes by mirroring brain processes, opening doors for applications in medical diagnostics, drug discovery and beyond.

Scripps Research scientists and collaborators use an innovative set of machine-learning models to discover a record-breaking material for film capacitors, key components in many energy technologies.

New findings underscore the importance of ongoing surveillance for H5N1 mutations that pose risks to public health.

Funding from ARPA-H will be used to develop a vaccine for alphaviruses in preparation of major outbreaks in the U.S.

Technologies developed by both teams will map the human eye-brain connectome, extend the lifespan of the revived human eye, and help regenerate and monitor the optic nerve after a whole eye transplant.