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Where hypotheses become headlines: Featured coverage of the breakthroughs—and the people—driving our research forward

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The Scripps Research scientists leading the Huang Foundation-supported projects. From left: Terrence Messmer, Sarah Burbach, Matthew Holcomb, Bryan Briney, Stefano Forli, Benjamin Cravatt, Christopher Parker, Andrew Ward and Charles Bowman.
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Scripps Research garners major support for AI innovations in biomedicine with compute grant from Jen-Hsun and Lori Huang Foundation

Chi-Huey Wong.
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Scripps Research professor Chi-Huey Wong to receive ACS Alfred Bader Award

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  • Scripps Research scientists find new way to block alcohol addiction and ease withdrawal
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    Scripps Research scientists find new way to block alcohol addiction and ease withdrawal

    "The big takeaway here is that we have a new molecular target linked to alcohol addiction."

  • AbbVie and Calibr announce collaboration for next generation T-cell therapies
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    AbbVie and Calibr announce collaboration for next generation T-cell therapies

    Collaboration will focus on switchable CAR-T therapies aimed primarily at solid tumors.

  • Scripps Research study provides new clues to improving chemotherapies
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    Scripps Research study provides new clues to improving chemotherapies

    The work has important implications for understanding how human cancer cells develop resistance to natural product-based chemotherapies. 

  • Scientists find potential disease-fighting ‘warheads’ hidden in bacteria
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    Scientists find potential disease-fighting ‘warheads’ hidden in bacteria

    Bacteria found in soil may harbor a potential game-changer for drug design. 

  • Chemists achieve major milestone of synthesis: remote chiral induction
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    Chemists achieve major milestone of synthesis: remote chiral induction

    The method is likely to be adopted widely for the making of prospective drugs and other chemical products.

  • Scripps Research chemists design ‘miniecosystems’ to test drug function
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    Scripps Research chemists design ‘miniecosystems’ to test drug function

    Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized ‘miniecosystems’ to quickly see if a molecule can function as a potential therapeutic.

  • Researchers uncover new ‘proofreading’ mechanism in gene translation
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    Researchers uncover new ‘proofreading’ mechanism in gene translation

    The team found that when the protein that controls the process is defective, in nerve cells in particular, it can allow dangerous, misfolded proteins to accumulate.

  • Scripps Research ranked top nonprofit scientific institute in United States
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    Scripps Research ranked top nonprofit scientific institute in United States

    Scripps Research is the top stand-alone scientific institute in the United States for producing high-quality research, according to a recently released Nature Index ranking.

  • Two-pronged antibodies draw immune killers directly to cancer cells
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    Two-pronged antibodies draw immune killers directly to cancer cells

    Proteins with a selective targeting system can zero in on a protein found on the surface of several types of cancer cells.

  • Novel RNA-modifying tool corrects genetic diseases, including driver of triple-negative breast cancer
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    Novel RNA-modifying tool corrects genetic diseases, including driver of triple-negative breast cancer

    “This research further shows that RNA is indeed a viable target to make medicines.”

  • Autism research to advance with $3.6 million NIH grant to Scripps Florida team
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    Autism research to advance with $3.6 million NIH grant to Scripps Florida team

    The grant builds upon previous work from the Rumbaugh lab that uncovered a sensitive period in brain development.

  • John C. Martin, Gilead Chairman, joins the Board of Directors at The Scripps Research Institute
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    John C. Martin, Gilead Chairman, joins the Board of Directors at The Scripps Research Institute

    Widely respected for his scientific and business leadership, Martin was named best CEO in 2015 by the investment research company Morningstar. 

  • Sherry Lansing, trailblazing studio executive, joins the Board of Directors at The Scripps Research Institute
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    Sherry Lansing, trailblazing studio executive, joins the Board of Directors at The Scripps Research Institute

    Lansing is a co-founder of the Stand Up To Cancer initiative, which funds and facilitates patient-focused, collaborative cancer research.

  • Putting blood pressure on the map—literally
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    Putting blood pressure on the map—literally

    New study shows the importance of considering local temperature and geography when measuring cardiovascular health.

  • Scripps Research scientists move forward with work to study opioid alternatives
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    Scripps Research scientists move forward with work to study opioid alternatives

    Amidst a nation-wide opioid epidemic, scientists at The Scripps Research Institute are making strides in developing new, non-opioid pain medications. 

  • Tumor-like spheres help scientists discover smarter cancer drugs
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    Tumor-like spheres help scientists discover smarter cancer drugs

    "Until now, most of the research to screen for cancer drugs has used cells that are growing flat on a plate."

    Timothy Spicer
  • The Joy of Neurons
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    The Joy of Neurons

    Scientists at The Scripps Research Institute have devised what they call a “neuronal cookbook” for turning skin cells into different types of neurons.

  • Scripps Research chemist receives prestigious Royal Society of Chemistry Award
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    Scripps Research chemist receives prestigious Royal Society of Chemistry Award

    Floyd Romesberg, PhD, professor at The Scripps Research Institute, has won the 2018 Royal Society of Chemistry (RSC) Bioorganic Chemistry Award.

  • Scientists investigate new strategy to treat spinal muscular atrophy in infants
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    Scientists investigate new strategy to treat spinal muscular atrophy in infants

    Scientists at Calibr and Scripps Research have discovered how a potential new drug targets this deadly disease.

    Calibr-Skaggs Kristen Johnson
  • Wriggling tadpoles may hold clue to how autism develops
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    Wriggling tadpoles may hold clue to how autism develops

    A neuroscientist explores the root of plasticity in the brain.

  • Scripps Research scientists receive $12 million for malaria and flu vaccine research
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    Scripps Research scientists receive $12 million for malaria and flu vaccine research

    "We have a great team here at Scripps Research for rational design of vaccines."

  • Steve Steinhubl, Eric Topol and Katie Baca-Motes
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    Launch of All of Us Research Program heralds new era for technology-driven citizen science and precision medicine

    Scripps Translational Science Institute to lead the national Participant Center and the program’s use of mobile technologies for each individual to collect their health data.

  • Scripps Research team receives $7.5 million in grants for studies on cocaine, oxycodone addiction
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    Scripps Research team receives $7.5 million in grants for studies on cocaine, oxycodone addiction

    “Scripps Research is one of the only places in the world where you can do this type of large-scale behavioral study..."

  • Translational Institute receives $34 million NIH Clinical and Translational Science Award
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    Translational Institute receives $34 million NIH Clinical and Translational Science Award

    "We are thrilled to have the NIH’s continued support for our efforts to advance individualized medicine, both in care of patients and in training of young physicians and scientists."

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