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Chi-Huey Wong.
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Scripps Research professor Chi-Huey Wong to receive ACS Alfred Bader Award

Dissociation of the four-part TTR protein. The energy landscape shows stable states toward the bottom and unstable transition states toward the top. In the canonical pathway (red), the tetramer (T) dissociates via a native-like, compact transition state (‡1) into transient dimer intermediates (D) before full dissociation into monomers (M). In the newly discovered alternative pathway (blue), the tetramer dissociates through a more expanded transition state (‡2) directly into monomers. Credit: Jan-Hannes Schäfer, Scripps Research
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Scientists discover a new way that a disease-linked protein comes apart

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  • Scripps Research ranked top nonprofit scientific institute in United States
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    Scripps Research ranked top nonprofit scientific institute in United States

    Scripps Research is the top stand-alone scientific institute in the United States for producing high-quality research, according to a recently released Nature Index ranking.

  • Two-pronged antibodies draw immune killers directly to cancer cells
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    Two-pronged antibodies draw immune killers directly to cancer cells

    Proteins with a selective targeting system can zero in on a protein found on the surface of several types of cancer cells.

  • Novel RNA-modifying tool corrects genetic diseases, including driver of triple-negative breast cancer
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    Novel RNA-modifying tool corrects genetic diseases, including driver of triple-negative breast cancer

    “This research further shows that RNA is indeed a viable target to make medicines.”

  • Autism research to advance with $3.6 million NIH grant to Scripps Florida team
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    Autism research to advance with $3.6 million NIH grant to Scripps Florida team

    The grant builds upon previous work from the Rumbaugh lab that uncovered a sensitive period in brain development.

  • John C. Martin, Gilead Chairman, joins the Board of Directors at The Scripps Research Institute
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    John C. Martin, Gilead Chairman, joins the Board of Directors at The Scripps Research Institute

    Widely respected for his scientific and business leadership, Martin was named best CEO in 2015 by the investment research company Morningstar. 

  • Sherry Lansing, trailblazing studio executive, joins the Board of Directors at The Scripps Research Institute
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    Sherry Lansing, trailblazing studio executive, joins the Board of Directors at The Scripps Research Institute

    Lansing is a co-founder of the Stand Up To Cancer initiative, which funds and facilitates patient-focused, collaborative cancer research.

  • Putting blood pressure on the map—literally
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    Putting blood pressure on the map—literally

    New study shows the importance of considering local temperature and geography when measuring cardiovascular health.

  • Scripps Research scientists move forward with work to study opioid alternatives
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    Scripps Research scientists move forward with work to study opioid alternatives

    Amidst a nation-wide opioid epidemic, scientists at The Scripps Research Institute are making strides in developing new, non-opioid pain medications. 

  • Tumor-like spheres help scientists discover smarter cancer drugs
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    Tumor-like spheres help scientists discover smarter cancer drugs

    "Until now, most of the research to screen for cancer drugs has used cells that are growing flat on a plate."

    Timothy Spicer
  • The Joy of Neurons
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    The Joy of Neurons

    Scientists at The Scripps Research Institute have devised what they call a “neuronal cookbook” for turning skin cells into different types of neurons.

  • Scripps Research chemist receives prestigious Royal Society of Chemistry Award
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    Scripps Research chemist receives prestigious Royal Society of Chemistry Award

    Floyd Romesberg, PhD, professor at The Scripps Research Institute, has won the 2018 Royal Society of Chemistry (RSC) Bioorganic Chemistry Award.

  • Scientists investigate new strategy to treat spinal muscular atrophy in infants
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    Scientists investigate new strategy to treat spinal muscular atrophy in infants

    Scientists at Calibr and Scripps Research have discovered how a potential new drug targets this deadly disease.

    Calibr-Skaggs Kristen Johnson
  • Wriggling tadpoles may hold clue to how autism develops
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    Wriggling tadpoles may hold clue to how autism develops

    A neuroscientist explores the root of plasticity in the brain.

  • Scripps Research scientists receive $12 million for malaria and flu vaccine research
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    Scripps Research scientists receive $12 million for malaria and flu vaccine research

    "We have a great team here at Scripps Research for rational design of vaccines."

  • Steve Steinhubl, Eric Topol and Katie Baca-Motes
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    Launch of All of Us Research Program heralds new era for technology-driven citizen science and precision medicine

    Scripps Translational Science Institute to lead the national Participant Center and the program’s use of mobile technologies for each individual to collect their health data.

  • Scripps Research team receives $7.5 million in grants for studies on cocaine, oxycodone addiction
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    Scripps Research team receives $7.5 million in grants for studies on cocaine, oxycodone addiction

    “Scripps Research is one of the only places in the world where you can do this type of large-scale behavioral study..."

  • Translational Institute receives $34 million NIH Clinical and Translational Science Award
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    Translational Institute receives $34 million NIH Clinical and Translational Science Award

    "We are thrilled to have the NIH’s continued support for our efforts to advance individualized medicine, both in care of patients and in training of young physicians and scientists."

  • Molecule that dilates blood vessels hints at new way to treat heart disease
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    Molecule that dilates blood vessels hints at new way to treat heart disease

    Scientists have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate. 

  • Your immune system holds the line against repeat invaders, thanks to this molecule
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    Your immune system holds the line against repeat invaders, thanks to this molecule

    Researchers found a transcription factor protein called Runx3 puts dividing T cells on track to becoming memory T cells. 

  • Cancer researchers receive more than $2 million to eradicate common form of leukemia
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    Cancer researchers receive more than $2 million to eradicate common form of leukemia

    “There is a dire need for the development of new, effective and safe therapies against chronic lymphocytic leukemia.”

  • Healthy red blood cells owe their shape to muscle-like structures
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    Healthy red blood cells owe their shape to muscle-like structures

    A new discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.

  • Families facing rare neurological disease drive groundbreaking research
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    Families facing rare neurological disease drive groundbreaking research

    Scripps Research scientists uncover role of key protein in genetic disease Charcot-Marie-Tooth with public support.

  • Former Scripps Research postdocs receive prestigious awards
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    Former Scripps Research postdocs receive prestigious awards

    Balzan Prize and Coley Award goes to former Scripps Research postdocs.

  • Discovery paves way for better flu prevention, treatment
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    Discovery paves way for better flu prevention, treatment

    Influenza kills thousands of Americans each year. Now a new study shows how we could improve flu vaccines.

Groundbreaking Science.
Life-changing Medicine.