News

Combining precise genome engineering and protein activity profiling to methodically study thousands of cancer genes, Scripps Research scientists were able to pinpoint promising cancer drug targets.

The prestigious award will support Lasker’s inventive research in membraneless organelles and their application in neurodegenerative diseases.

The prestigious award will support Bollong’s research identifying new molecular targets and therapeutics, including in regenerative organ repair.

Dawson is honored with the Arthur C. Cope Late Careers Scholar Award for his foundational contributions in organic chemistry.

The method represents a new toolkit for making drugs and other compounds.

New findings suggest that treating insomnia can stop opioid-seeking behavior, even after ending treatment.

Bill & Melinda Gates Foundation award to support the development of multi-pathogen wastewater surveillance tools and protocols.

Scripps Research scientists’ discovery could lead to new weight loss and metabolic health treatments.

The sensory receptor PIEZO1 changes shape in response to mechanical stimuli. The super high-resolution microscopy technology used in this discovery is a breakthrough in enabling protein structures to be studied within the cellular environment.

Scripps Research-developed antibody therapy appears to have advantages over existing opioid-overdose treatments.

Scripps Research scientists discovered the unique molecular structure, which could have implications in age-related diseases like neurodegeneration.

Scripps Research scientists show that the receptor PIEZO2 in sensory neurons controls gut motility and transit time, which are important for digestion and nutrient absorption.

The expanded strategic collaboration will advance several innovative assets across AbbVie’s core therapeutic growth areas including immunology, oncology, neuroscience.

Calibr scientists engineered a cytokine protein that has shown evidence of providing neuroprotective effects to Parkinson’s disease patients.

In a preclinical study, Scripps Research scientists show that the drug ADX106772 (Addex Therapeutics) reduced oxycodone intake and relapse, without disrupting the brain’s natural reward system.

Machine-learning system effectively predicts emergence of prominent variants.

Navacaprant, a monotherapy discovered at Scripps Research, showed clinically meaningful improvements for people with moderate-to-severe MDD in a recently completed Phase 2 study.

The program grant will support the development of high-affinity antibodies that can target skin and lung infections, as well as sexually transmitted diseases.

A leader in viral pathogenesis, Oldstone helped shape our modern understanding of viruses and how the immune system responds to these microbial threats.

Scripps Research study shows that analyzing T cells in blood samples could be used to select at-risk patients for type 1 diabetes preventive therapy.

The discovery by scientists from Scripps Research and Cardiff University paves the way for clinical trials that use patients’ own cells to treat Parkinson’s disease.

Eschenmoser pioneered key reactions in synthetic chemistry and shaped the understanding of how life may have first originated on Earth.

The award renews support for Scripps Research Translational Institute and partner organizations involved in expanding one of the largest and most inclusive health data resources of its kind.

The Translational Institute is harnessing genomic and digital technologies with machine learning to revolutionize health research.