News

New drugs for neurodegenerative and genetic disorders making their way to the marketplace.

Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats—with the flip of a switch.

New book Deep Medicine released and garners significant media attention. Click to read more and review ongoing media coverage. 

In a breakthrough with applicability across many flu strains, researchers find a potential small molecule that mimics antibodies to treat disease.

For the last decade researchers have been developing a drug candidate that eases inflammation and protects brain cells from damage. Now, research shows another potential application: treating Alzheimer’s disease. 

In a New York Times op-ed, Eric Topol, MD, founder and director of Scripps Research Translational Institute, discusses the science of nutrition and the need for diet to be individualized.

Scripps Research assistant professor Luke Lairson, PhD, and colleagues have discovered a compound that potently and selectively kills the stem-like cells that make glioblastoma brain cancers so deadly.

Program supports workforce training recommended by Eric Topol, MD, in an independent review of the digital future of the National Health Service.

Inspired by electric car batteries, researchers developed a battery-like system that allows them to make potential advancements for the manufacturing of medicines.

Scripps Research professor Ramanarayanan Krishnamurthy, PhD, has been named co-leader of a new NASA initiative to investigate how life emerged from Earth’s early environments.

Cells removed from patients’ bloodstreams and genetically altered may allow more effective vaccines for HIV, influenza, hepatitis.

Neuroscientists Giordano Lippi and Li Ye have received grants from the Whitehall Foundation to support their studies into brain function.

For breast cancer patients with dwindling options, switching on HER2 sensitivity might be life-changing. Disney’s group described shifting three different cancer cell lines from HER2-negative status to HER2-positive status with the addition of a selective micro-RNA binding molecule.

Synapse instability may underlie many neurodegenerative diseases, including Alzheimer’s. A new study from the lab of Brock Grill, PhD, sheds light on synapse maintenance.  

Chemistry Professor Matthew D. Disney, PhD, of Scripps Research in Jupiter, Florida, has been awarded the Raymond and Beverly Sackler International Prize in Chemistry from Tel Aviv University.

The American Association for Cancer Research has named Michalina Janiszewska, PhD, a “NextGen Star”.

The American Society for Microbiology has elected Scripps Research Professor Michael Farzan, PhD, to its American Academy of Microbiology.

Huge-scale sequencing study also points to future use of human “antibody repertoires” for disease diagnosis and vaccine design.

Mice lacking BDNF in certain brain regions showed signs of anxiety. They also had an elevated basal metabolic rate.

Defects in the transport of cells’ energy organelles are a suspected cause of diseases including Alzheimer’s, ALS, Huntington’s and Parkinson’s. A new study uncovers how mitochondria move in neurons.

When alcohol reaches our nerve cells, the alcohol connects with intermediary molecules on the neuron’s membrane surface to produce its intoxicating effects, indirectly.

Lasmézas and her team find that enzymes modify tau to create tau-a-synuclein clumps on mitochondria, leading ultimately to the death of neurons.

This video by Boston Globe’s STAT magazine features Calibr’s ReFRAME collection, a drug repurposing project that’s finding ways to treat new diseases with existing drugs.

Individual neurons can have multiple kinesins in motion at the same time, moving like trucks on a highway, a study from the Puthanveettil lab finds.