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Where hypotheses become headlines: Featured coverage of the breakthroughs—and the people—driving our research forward

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The Scripps Research scientists leading the Huang Foundation-supported projects. From left: Terrence Messmer, Sarah Burbach, Matthew Holcomb, Bryan Briney, Stefano Forli, Benjamin Cravatt, Christopher Parker, Andrew Ward and Charles Bowman.
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Scripps Research garners major support for AI innovations in biomedicine with compute grant from Jen-Hsun and Lori Huang Foundation

Chi-Huey Wong.
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Scripps Research professor Chi-Huey Wong to receive ACS Alfred Bader Award

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  • Scripps Research spinoff Abide Therapeutics to be acquired by Danish pharma company Lundbeck
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    Scripps Research spinoff Abide Therapeutics to be acquired by Danish pharma company Lundbeck

    Abide Therapeutics, Inc., a clinical-stage biopharmaceutical company founded by Scripps Research professors Benjamin Cravatt, PhD, and Dale Boger, PhD, will be acquired by the Danish pharmaceutical firm H. Lundbeck A/S (Lundbeck).

  • FDA approves Scripps Research-originated drug tafamidis for cardiomyopathy
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    FDA approves Scripps Research-originated drug tafamidis for cardiomyopathy

    The U.S. Food and Drug Administration has approved tafamidis for the treatment of heart disease (cardiomyopathy) caused by mutant or wild-type transthyretin aggregation in adults.

    Evan Powers
  • Scripps Research selects high school summer interns for 15th annual Kenan Fellows program
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    Scripps Research selects high school summer interns for 15th annual Kenan Fellows program

    Eleven students from high schools across Palm Beach County will join biomedical research laboratories at Scripps Research in Jupiter, Florida this summer as part of the institute’s 15th annual high school student internship program.

  • Vaccine shows lasting effects against deadly synthetic opioids
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    Vaccine shows lasting effects against deadly synthetic opioids

    Scientists at Scripps Research have developed an experimental vaccine that may one day help treat addiction to fentanyl, a highly potent opioid linked to an epidemic of overdoses and fatalities in recent years.

  • Gene repair improves memory and seizures in adult autism model
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    Gene repair improves memory and seizures in adult autism model

    There may be reason to treat severe neurodevelopmental disorders at any stage of life once options become available, a new study of SYNGAP1 related autism suggests.

  • New ‘POWERMOM’ app launched to study maternal health
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    New ‘POWERMOM’ app launched to study maternal health

    Researchers at the Scripps Research Translational Institute have launched a new digital research platform called POWERMOM that enables pregnant women anywhere in the United States to contribute their health information to the study using a smartphone app.

  • Chemist Jin-Quan Yu of Scripps Research elected to American Academy of Arts and Sciences
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    Chemist Jin-Quan Yu of Scripps Research elected to American Academy of Arts and Sciences

    The American Academy of Arts and Sciences, one of the world’s most prestigious honor societies, has named Scripps Research chemist Jin-Quan Yu, PhD, as an elected member of its 2019 class. Yu is known globally for his groundbreaking work in the field of organic synthetic chemistry.

  • Sydney Brenner, Nobel laureate and genetics pioneer, dies at 92
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    Sydney Brenner, Nobel laureate and genetics pioneer, dies at 92

    Brenner devoted his career to conducting groundbreaking basic research. His many contributions to molecular biology led to his being co-awarded the Nobel Prize in Physiology or Medicine in 2002.

  • New study suggests oxytocin could help treat alcohol addiction
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    New study suggests oxytocin could help treat alcohol addiction

    In a study with the National Institute on Drug Abuse, scientists at Scripps Research discovered that oxytocin blocked enhanced drinking in alcohol-dependent rats, concluding that targeting the oxytocin system may be a successful pharmaceutical approach for treating alcohol-use disorder.

  • Molecules that prevent protein misfolding point to new type of therapy for AL amyloidosis
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    Molecules that prevent protein misfolding point to new type of therapy for AL amyloidosis

    Scientists at Scripps Research have identified a group of small molecules that prevent structural changes to proteins that are at the root of AL amyloidosis, a progressive and often fatal disease.

  • Mouse model develops Parkinson’s just like humans, opening the door to more accurate drug screening
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    Mouse model develops Parkinson’s just like humans, opening the door to more accurate drug screening

    New research will now make it possible to screen drug candidates more reliably and investigate the root cause of Parkinson’s disease.

    Steven Reed
  • Scripps Research receives highest possible charity rating
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    Scripps Research receives highest possible charity rating

    Charity Navigator awards Scripps Research four stars for exceeding industry standards in financial health, accountability and transparency.

  • Chemistry feat suggests the building blocks of DNA and RNA could have appeared together before life began on earth
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    Chemistry feat suggests the building blocks of DNA and RNA could have appeared together before life began on earth

    Scientists find evidence that RNA and DNA could have arisen from the same set of precursor molecules before life evolved four billion years ago.

  • Leading cause of muscular dystrophy in adults responds to new treatment
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    Leading cause of muscular dystrophy in adults responds to new treatment

    Currently there is no treatment for myotonic dystrophy type 1. Now, researchers say they have made a potential drug that targets a disease-causing RNA at the root of the disease.  

  • Scripps Research discoveries pave way to clinical trial of new type of HIV vaccine
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    Scripps Research discoveries pave way to clinical trial of new type of HIV vaccine

    The International AIDS Vaccine Initiative (IAVI) announced the start of a Phase I clinical trial to test a novel HIV vaccine candidate, an advance in vaccine design enabled by Scripps Research discoveries.

    HIV/AIDS Vaccines
  • Discovery of life-extension pathway in worms demonstrates new way to study aging
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    Discovery of life-extension pathway in worms demonstrates new way to study aging

    New method could enable faster study of strategies to combat age-related diseases.

  • Trio of new medicines originate from Scripps Research discoveries
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    Trio of new medicines originate from Scripps Research discoveries

    New drugs for neurodegenerative and genetic disorders making their way to the marketplace.

  • Scientists hunt down the brain circuit responsible for alcohol cravings
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    Scientists hunt down the brain circuit responsible for alcohol cravings

    Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats—with the flip of a switch.

  • Robot hand holding a red apple.
    News

    Eric Topol pens book on artificial intelligence in medicine

    New book Deep Medicine released and garners significant media attention. Click to read more and review ongoing media coverage. 

  • Scientists discover a potential strategy to treat influenza A
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    Scientists discover a potential strategy to treat influenza A

    In a breakthrough with applicability across many flu strains, researchers find a potential small molecule that mimics antibodies to treat disease.

  • News

    Stroke drug treats mouse model of Alzheimer’s disease

    For the last decade researchers have been developing a drug candidate that eases inflammation and protects brain cells from damage. Now, research shows another potential application: treating Alzheimer’s disease. 

    Translational Medicine Alzheimer’s Disease
  • The A.I. Diet
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    The A.I. Diet

    In a New York Times op-ed, Eric Topol, MD, founder and director of Scripps Research Translational Institute, discusses the science of nutrition and the need for diet to be individualized.

  • Promising compound selectively kills brain cancer stem cells
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    Promising compound selectively kills brain cancer stem cells

    Scripps Research assistant professor Luke Lairson, PhD, and colleagues have discovered a compound that potently and selectively kills the stem-like cells that make glioblastoma brain cancers so deadly.

  • UK National Health Service launches Topol Program for Digital Fellowships in Healthcare
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    UK National Health Service launches Topol Program for Digital Fellowships in Healthcare

    Program supports workforce training recommended by Eric Topol, MD, in an independent review of the digital future of the National Health Service.

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