News

The virus that causes COVID-19 uses a clutch-like shifter to enable transcription of one RNA string into multiple proteins, and therein lies a vulnerability. A proof-of-concept study from Disney lab shows it’s possible to eliminate that shifter with an RNA-binding medicinal compound linked to a “trash this” signal.

Early detection of atrial fibrillation can help significantly reduce the risk of stroke, and digital health tools may be the answer.

Discoveries from Boger’s lab have led to unique strategies and methods for making molecules, as well as durable antibiotics, novel ways to treat chronic pain, and an experimental cancer vaccine.

The novel vaccine technology, developed at Scripps Research, uses virus-like particles to elicit high levels of protective antibodies.

Several mutant forms of NEMF in mice interfered with ribosome-associated quality control and resulted in neuromuscular, neurodegenerative or other disease.

Wearable devices give scientists a powerful new tool for sleep studies.

In a new study, Scripps Research scientists pave the way toward creating a medicinal compound that imitates the valuable effects of reduced body temperature.

A fundamental neuroscience discovery may propel future efforts to boost vision lost due to retina degeneration and enable light-sensing prosthetics that cure blindness.

Scientists in the United States and West Africa to develop research network to rapidly respond to current and future infectious disease outbreaks.

Damaged hearts require stem cell activation to heal, but heart attack silences a key signaling molecule. A compound discovered in Disney lab reactivates its production, in cell-based studies. 

Shenvi and Roberts are recognized for their contributions in organic synthesis and the development of medicinally useful substances.

A small molecule that activates the immune protein STING shows promising results against tumors.

These molecules, called terpenes, are potential starting points for new drugs and other high-value products, marking an important development for multiple industries.

Electron microscopy showed that the coronavirus spikes maintained the desired shape in the vaccine, which should help stimulate an appropriate immune response.

Unlike traditional vaccine clinical trials, this study provided a clear and comprehensive picture of a vaccine’s antibody-response landscape.

Collaborating labs at Scripps Research developed a way to seamlessly create the compound's complex structure.

Chemists at Scripps Research have reported a promising but mysterious finding in experiments with a potential vaccine that is meant to combat heroin addiction.

Advanced chemistry techniques reveal thousands of sites on immune proteins where drug molecules may be able to bind, opening new possibilities for treating immune-driven conditions.

Scripps Research is collaborating with frontline workers at the San Diego Metropolitan Transit System and Scripps Health to help detect and track viral illnesses in near real-time.

The compound hits a vulnerable spot on multiple strains of the flu, attacking the virus in a whole new way.

The $25,000 award will support scientific research in organic chemistry, with a view to enabling drug discovery.

Scientists reveal a new role for cells that already are known to be implicated in many other brain-based diseases, including Alzheimer’s and Huntington’s.

A new study reveals how two key neural circuits dictate the choice between social approach and avoidance.  The findings will enable researchers to evaluate social interventions in autism.

Findings of the new study support many vaccine strategies currently being used to tackle the new coronavirus.