20200415-drug-repurposing-reframe-covid19

New method illustrates how to build a tough chemical bond found in carbohydrate-based drugs, such as those for treating diabetes.

A Scripps Research team has captured the first high-resolution structural images of human Argonaute 2 in its cutting-ready state, revealing why some small interfering RNA (siRNA) molecules work better than others and how to design more effective ones for this emerging therapy.

Scripps Research scientists showed that blocking an immune molecule tied to inflammation reduced alcohol consumption in mice.

New findings from Scripps Research show that disabling a single bacterial protein can restore vancomycin’s power against resistant bacteria–and point to a new strategy for overcoming antibiotic resistance.

Scripps Research discovery finds that restoring the naturally occurring compound erucamide in the eye stabilized tissue in preclinical models of retinal degeneration.