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  Study uncovers disrupted brain balance in alcohol dependence

  Experiments show how dependence on alcohol rewires the brain's "go" and "stop drinking" signaling systems, with implications for preventing relapse.

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  New technique lights up where drugs go in the body, cell by cell

  Scripps Research scientists developed a technique that maps drug binding in individual cells throughout the body, potentially explaining side effects and guiding safer drug development.

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  A jolt to the system: Scripps Research biophysicists uncover new electrical transmission in cells

  “Tiny biological batteries” can change the cell membrane’s electrical properties—a discovery that has big implications for health, as many essential cellular processes hinge upon precise electrical activity.

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  Study reveals a key hormonal circuit in the kidneys

  Scripps Research scientists identify the protein that helps kidney cells regulate renin, providing foundational insight into how kidneys function.

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  Nanoparticle vaccine strategy could protect against Ebola and other deadly filoviruses

  Scripps Research scientists turn nanoparticles into virus “showcases” to help the immune system recognize deadly threats.

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  Study reveals high stakes of early immune development—and a potential probiotic fix

  Scripps Research scientists find that certain gut bacteria are essential for building immune defenses during infancy, pointing to new strategies for protecting children’s health.

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  Scripps Research team pioneers an efficient way to stereoselectively add fluorine to drug-like molecules

  A new method uses a novel catalyst and inexpensive fluoride salts to modify the most common chemical bonds—opening doors to new medicines and improved medical imaging.

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  An easier approach to recreate the powerful nerve-blocking molecule found in shellfish

  A Scripps Research-led study resolves the challenge of synthesizing saxitoxin, paving the way for new possibilities in pain management.

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  Scientists find cancer weak spot in backup DNA repair system

  New findings from Scripps Research reveal how certain tumors survive DNA damage—and point to a strategy for targeting them.

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  Scripps Research scientists receive $1.1 million to advance AI modeling for HIV vaccine development

  New AI system helps scientists rapidly pinpoint the most promising paths to an HIV vaccine.