News Tag: Srinivasa Subramaniam

Huntington’s disease may be driven by slowed protein-building machinery in cells

The results of a new study suggest a possible route for developing therapeutics, and may have implications for multiple neurodegenerative diseases in which ribosome stalling appears to play a role.

Dangerous side effect of widely used psychiatric drug may be treatable with existing medicine

A mouse study on the brain’s striatum region reveals an unexpected but important finding.

Huntington’s disease progression involves DNA damage sensor

Huntington’s disease progression involves a promoter of inflammation and autophagy, the cellular housekeeping process, a new study finds.  

Parkinson’s dyskinesia mechanism explained

The mechanism underlying Parkinson’s dyskinesia has been unknown, until now. An international collaboration led by Scripps Research, Florida has found a key cause, and with it, potentially, a new route to providing relief.

Protein that polices mitochondria in brain’s striatum may underlie Huntington’s selective damage, study finds

A system for recycling damaged mitochondria in the brain's striatal cells normally maintains health, but it goes awry in Huntington's disease due to a protein called Rhes, a new study finds. The discovery offers a new strategy for developing treatments for Huntington's and possibly other neurodegenerative diseases that feature selective tissue loss.

Nanotubes enable travel of Huntington’s disease protein

Nanotube tunnels built with the help of the Rhes protein serve as bridges for the toxic Huntington’s disease protein, a new study finds.

Scripps Florida Scientists Uncover Potential Driver of Age- and Alzheimer’s-Related Memory Loss

Scripps Florida Scientists Pinpoint Regulator of Amphetamine-Induced Motor Activity