Nuclear Magnetic Resonance
The Research Services’ Nuclear Magnetic Resonance Facility provides state-of-the-art NMR spectroscopy to researchers in Scripps Research, as well as spectral service to local biotech communities.
The Facility houses a total of six NMR spectrometers:
- Bruker AVIII HD 600 NMR spectrometer equipped with a 5 mm CPQCI (H-C-N-P) CryoProbe, and a SampleCase-24 sample changer.
- This spectrometer also has a 1.7 mm CPTCI (H-C-N) CryoProbe. This probe can be installed upon requested for experiments on micro-gram scale compounds.
- Bruker AVIII HD 600 NMR spectrometer equipped with a 5 mm CPDCH (C-H) CryoProbe.
- This CryoProbe provides high sensitivity for C-13 NMR experiments.
- Bruker AV NEO 500 NMR spectrometer with a 5 mm BBFO Smart Probe and a SampleCase-24 sample changer.
- Bruker AVIII 400 NMR spectrometer equipped with a 5 MM BBFO probe, and a B-ACS 120 sample changer.
- Bruker AV NEO 399 NMR spectrometer equipped with a 5 mm BBFO Smart Probe.
- All BBFO probes have the capabilities to perform NMR experiments on nuclei with resonance frequencies between Ag-109 and P-31, as well as H-1, and F-19.
- JEOL JNM-ECZ400R NMR spectrometer equipped with a Royal HFX probe, and an Auto Sample Changer for 64 samples. This three channel system is capable of observing X nucleus resonance with simultaneous H-1 and F-19 decoupling.
All NMR spectrometers are setup for routine high resolution solution state 1D and 2D NMR experiments.