How the nervous and immune systems coordinate inflammation

In a special year-end episode of Science Changing Life, we’re revisiting five moments from 2025 that continue to shape how we think about science. Featuring insights from Scripps Research experts across genetics, infectious disease, public health surveillance and chronic illness, this episode features some of this year’s most memorable soundbites.

Members of the public were invited to meet the San Diego scientists leading groundbreaking biomedical research when Scripps Research held its second annual Discovery Day at the Fleet Science Center in Balboa Park on Sunday, November 9, 2025. More than 60 Scripps Research graduate students and postdoctoral scholars shared the excitement of scientific discovery at more than a dozen hands-on activity tables. Visitors experienced demonstrations and explored topics ranging from chemistry, neuroscience, viruses and vaccines, aging research, cancer biology, the gut microbiome, and much more.

The second annual Scripps Research Biotech Innovation Summit convened in La Jolla this October, bringing together thought leaders from across the biotech spectrum for a dynamic program of keynote presentations, fireside chats, pitches and collaborative networking opportunities. Event attendees engaged directly with Scripps Research investigators pioneering early-stage innovation and the programming showcased how strategic partnerships between academia and industry can transform breakthrough discoveries into therapies that address urgent medical needs.

In the world of immunology, “gut reactions” take on a whole new meaning—not emotions, but signals from tiny organisms found in the gastrointestinal tract. And at Scripps Research, Professor Howard Hang explores the surprising power of some of the smallest inhabitants: microbes. These trillions of bacteria living in the gut communicate with human cells to shape immunity, metabolism and even how the body responds to disease treatments.