What’s next for IBD care: Insights from a surgeon-scientist
September 2025 | 22 min 57 sec
The data is clear: inflammatory bowel diseases like ulcerative colitis and Crohn’s are on the rise worldwide. In this episode, we sit down with Dr. Amy Lightner—VP of Clinical Development at Calibr-Skaggs and colorectal surgeon at Scripps Clinic—to explore what drives these diseases, an upcoming phase 2 clinical trial for a new regenerative medicine, and how she balances life between the operating room and the research lab.
Episode topics: Inflammatory bowel disease; Crohn’s disease; ulcerative colitis; colon cancer; pouchitis; IBD phase 2 clinical trial; CLF065; colorectal surgery

The award-winning Science Changing Life podcast offers an inside look into how Scripps Research scientists are solving the most pressing mysteries in human health and disease. Join hosts Lauren Fish and Melissa Suran, PhD, as they speak with world-class scientists at the forefronts of immunology, infectious disease, artificial intelligence, personalized medicine, neuroscience and much more.
Science Changing Life gives listeners a glimpse into the people behind the science, their motivations, paths to discovery, and how they’re changing the world.