News Tag: Parkinson's Disease

Study optimizes patient-specific stem cell-based therapy for Parkinson’s disease

The discovery by scientists from Scripps Research and Cardiff University paves the way for clinical trials that use patients’ own cells to treat Parkinson’s disease.

RNA-targeting strategy successfully blocks a vexing driver of Parkinson’s disease

A drug-like compound is able to selectively prevent production of the protein underlying most causes of Parkinson’s disease, alpha-synuclein.

Parkinson’s-linked gene product may be druggable, structural study finds

A new Scripps Research study finds that receptors for a Parkinson’s-associated gene product have a pocket needed to bind to other molecules, opening the ability to more accurately probe its role in disease, and possibly develop a new class of therapies.

Biologists show inner workings of cellular ‘undertaker’

Scientists from Scripps Research deciphered how the proteasome converts energy into mechanical motion that untangles and unfolds proteins for destruction. The findings, published in Science, could help us understand how proteasomes keep diseases such as Parkinson’s and Alzheimer’s at bay.