Peter Schultz, PhD
President and CEO
Department of Chemistry
L.S. “Sam” Skaggs Presidential Chair
Research Focus
Our research program combines the tools and principles of chemistry with the molecules and processes of living cells to synthesize new molecules and molecular assemblies with novel physical, chemical and biological functions. By studying the structure and function of the resulting molecules, new insights can be gained into the mechanisms of complex biological and chemical systems. Active research projects span the interface of biology, chemistry, and materials science, and include:
-The development and application of methods for adding new building blocks to the genetic codes of prokaryotic and eukaryotic organisms
- The application of molecular diversity to problems in biological structure, recognition and catalysis, drug discovery, and materials science
- Chemical and genomics studies of stem cell biology, oncogenesis and orphan/neglected diseases
-Generation and characterization of catalytic antibodies
Select Publications
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Lemke, E. A.; Summerer, D.; Geierstanger, B. H.; Brittain, S. M.; Schultz, Peter G. Control of protein phosphorylation with a genetically encoded photocaged amino acid. Nature Chemical Biology 2007, 3, 769-772.
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Gruenewald, J.; Tsao, M. L.; Perera, R.; Dong, L. Q.; Niessen, F.; Wen, B. G.; Kubitz, Diane; Smider, Vaughn V.; Ruf, Wolfram; Nasoff, M.; Lerner, Richard A.; Schultz, Peter G. Immunochemical termination of self-tolerance. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 11276-11280.
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Liu, Chang C.; Mack, A. V.; Tsao, M. L.; Mills, Jeremy H.; Lee, Hyun S.; Choe, Hyeryun; Farzan, Michael; Schultz, Peter G.; Smider, Vaughn V. Protein evolution with an expanded genetic code. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 17688-17693.
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Lee, Hyun S.; Guo, J. T.; Lemke, E. A.; Dimla, R. D.; Schultz, Peter G. Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. Journal of the American Chemical Society 2009, 131, 12921-12923.
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Schultz, Peter G.; Schultz, Peter G. Synthesis at the Interface of Chemistry and Biology. Chemistry international 2014, 36, 3-8.
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Liu, Chang C.; Schultz, Peter G. Adding new chemistries to the genetic code. Annual Review of Biochemistry 2010, 79, 413-444.
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