M. Reza Ghadiri, PhD
Chair
Department of Chemistry
Darlene V. Shiley Chair in Chemistry
Research Focus
Our group is involved in a multidisciplinary research effort that uses disciplines ranging from synthetic organic and inorganic chemistry to materials science and recombinant DNA technology to develop novel methods for the rational design and construction of functional biomaterial-based structures. Our goal is to provide novel applications in the field of molecular and system engineering as well as advance our fundamental understanding of living chemical processes. Currently, research projects in our laboratory deal with various aspects of peptide and protein architecture and folding, design of synthetic receptors and enzymes, fabrication of novel biosensor arrays, self-replicating molecular systems, and self-organized nonlinear autocatalytic chemical networks and ecosystems selected references.
Links
New Study by Scientists at TSRI Suggests an Answer for One of the Oldest Questions in Biology
Select Publications
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Lin, V. S.; Motesharei, K.; Dancil, K. P.; Sailor, M. J.; Ghadiri, M. R. A porous silicon-based optical interferometric biosensor. Science 1997, 278, 840-843.
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Severin, K.; Lee, David H.; Kennan, A. J.; Ghadiri, M. R. A Synthetic Peptide Ligase. Nature 1997, 389, 706-709.
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Lee, David H.; Severin, K.; Yokobayashi, Yohei; Ghadiri, M. R. Emergence of symbiosis in peptide self-replication through a hypercyclic network. Nature 1997, 390, 591-594.
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Severin, K.; Lee, David H.; Martinez, J. A.; Vieth, Michal; Ghadiri, M. R. Dynamic error correction in autocatalytic peptide networks. Angewandte Chemie-International Edition 1998, 37, 126-128.
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