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Protein Profiling Method Reveals Many Potential New Drug Targets
TSRI Scientist Wins Prestigious Young Investigator Award
TSRI Awarded $11 Million Grant Renewal by NIAID for Long-Running Study of Immunity, Inflammation
TSRI Chemists Develop Inexpensive, Versatile Technique for Making RNA

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TSRI Scientist Wins Prestigious Young Investigator Award

Staff Scientist Kathryn Hastie of The Scripps Research Institute (TSRI) has won the 2017 William E. and Diane M. Spicer Young Investigator Award of Stanford Synchrotron Radiation Lightsource, for her persistent work to reveal the Lassa virus glycoprotein structure. The Spicer Young Investigator Award is presented each year to a new investigator who has made significant technical or scientific contributions that are beneficial to the Lightsource community.

TSRI Awarded $11 Million Grant Renewal by NIAID for Long-Running Study of Immunity, Inflammation

The Scripps Research Institute (TSRI) has been awarded a five-year, $11.2 million grant from the National Institute for Allergic and Infectious Diseases (NIAID), part of the National Institutes of Health. The award is a continuation of support for a long-running, collaborative project to reveal the detailed workings of the mammalian immune system. The principal investigator for the project is Richard J. Ulevitch, a professor in TSRI’s Department of Immunology. The chief research collaborators are Alan A. Aderem of the Center for Infectious Disease Research in Seattle, Garry P. Nolan of Stanford University, and Bruce A. Beutler, who helped co-found the project while at TSRI but is now at the University of Texas Southwestern.

Protein Profiling Method Reveals Many Potential New Drug Targets

Scientists at The Scripps Research Institute have invented a versatile method for identifying proteins that can feasibly be targeted with drugs to treat disease. Using the new method, published on July 31, 2017 in Nature Chemistry, the TSRI scientists from the Cravatt lab identified more than 100 human proteins that are likely to be targetable with small molecule, pill-based drugs. Some of these proteins already have been implicated in diseases such as cancer, but only a minority were previously known to be “druggable.”

TSRI Chemists Develop Inexpensive, Versatile Technique for Making RNA

Scientists in Floyed Romesberg’s lab have developed a highly efficient new method for making ribonucleic acid (RNA) molecules in the laboratory. The method, described in the July 26 issue of the Journal of the American Chemical Society, works both for ordinary RNA and for several types of modified RNA. It has the potential to bring down dramatically the cost of producing RNA for scientific and pharmaceutical applications.

  • TSRI Scientist Wins Prestigious Young Investigator Award
  • TSRI Chemists Develop Inexpensive, Versatile Technique for Making RNA
  • TSRI Awarded $11 Million Grant Renewal by NIAID for Long-Running Study of Immunity, Inflammation
  • Protein Profiling Method Reveals Many Potential New Drug Targets
  • TSRI Ranks No. 1 in Innovation Influence
  • Scripps Florida Scientists Identify Protein Deficiency Involved in Childhood Anemia and Cancers
  • One Cytokine To Control Multiple Cytokines
  • NIH-supported scientists elicit broadly neutralizing antibodies to HIV in calves
  • Scripps Florida Scientists Awarded $2 Million to Develop ‘Industrial Level’ Screening for Treatments of Autism-Related Intellectual Disability
  • Exercise Performance in Mice Depends on Circadian Rhythms
  • Scripps Florida Scientist and Collaborators Win $7 Million Grant to Develop New ALS Treatments
  • San Diego Team Tests Best Delivery Mode for Potential HIV Vaccine
  • Firefly Gene Illuminates Ability of Optimized CRISPR-Cpf1 to Efficiently Edit Human Genome
  • Perseverance Pays Off in Fight Against Deadly Lassa Virus