Class of '14

Doctorate of Philosophy

	Jason Robert Abbott Studies Toward the Total Synthesis of Incednine Advisor: William R. Roush, PhD, Associate Dean of Graduate Studies, Florida; Professor, Department of Chemistry

	Klaus Albertshofer Part 1: Diversity Oriented Construction of Carbocyclic Spiro-3 3'-Oxindole-Derived Core Structures via Asymmetric Organocatalytic Tandem Processes; Part 2: Assembly of Syn-1 2- Diol-Containing Target Molecules via Asymmetric Organocatalytic Aldol Reactions Advisor: Carlos F. Barbas III PhD, Professor, Departments of Chemistry and Cell and Molecular Biology

	Phillip Aoto Structure and Dynamics of a Protein Kinase Advisor: Peter E. Wright, PhD, Professor, Department of Integrative Structural and Computational Biology

	Siddaraju V. Boregowda TWIST1 Regulates Growth, Multi-potency and Non-progenitor Functions of Mesenchymal Stem Cells Advisor: Donald G. Phinney, PhD, Professor, Department of Molecular Therapeutics

	Ronald Leroy Coleman Regenerative Medicine and Multiple Sclerosis: Toward Clinical Intervention Advisor: Jeanne F. Loring, PhD, Professor of Developmental Neurobiology, Department of Chemical Physiology

	Peter S. Diez Stereoselective Synthesis of Skipped-Polyenes and Deoxypropionates via Titanium-Mediated Reductive Cross-Coupling of Allylic-Alcohols and Alkynes Advisor: Glenn Micalizio, PhD, Professor, Dartmouth College, Department of Chemistry

	Myles B.C. Dillon Understanding the Function of Arginine Methylation in Pancreatic Beta Cells: Developing Tools to Modulate the Activity of Protein Arginine Methyltransferases Advisor: Kerri A. Mowen, PhD, Assistant Professor, Department of Chemical Physiology

	Katharine K. Duncan α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase: Exploration of Conformational Constraints in the Acyl Side Chain Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

	Keary Mark Engle I. Ligand-Accelerated Catalysis in Palladium (II)-Mediated C-H Functionalization; II. Hydrogen Bonding Effects on the Reactivity of Fluoride Anion Advisor: Jin-Quan Yu PhD, Professor, Department of Chemistry

	Laurie Jeanne Gay Brain Metastasis Depends on Tumor Cell Initiated Coagulation and Tissue Factor Signaling Advisor: Brunhilde Felding, PhD, Associate Professor, Department of Chemical Physiology

	Will Ryan Gutekunst Synthesis of Cyclobutane Natural Products using C-H Functionalization Logic Advisor: Phil S. Baran PhD, Professor, Department of Chemistry

	Jennifer L. Hazen Reprogramming and Neuronal Genomes Advisor: Kristin K. Baldwin, PhD, Associate Professor, Department of Molecular and Cellular Neuroscience

	Pei-hsin Hsu In vivo Evidence for Ndc80p Regulated Kinetochore-Microtubule Slippage Advisor: Gaudenz Danuser, PhD, Professor, Department of Cell Biology, Harvard University

	Joseph G. Jardine Development of Germline-Targeting Immunogens and Determination of Minimal Maturation antibodies against HIV Requirements for VRC01-class Broadly Neutralizing Advisor: William G. Schief, PhD, Professor of Immunology, Department of Immunology and Microbial Science

	Mingchao Kang Genetic Incorporation of Unnatural Amino Acids and its Applications Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry

	Sung Eun Kim Ion channels in Mechano-and Thermo-sensation Advisor: Ardem Patapoutian, PhD, Professor, Department of Molecular and Cellular Neuroscience

	Jinny Kwong p38 MAPK Family: Their Regulation, Function and Role in Ras-induced Senescence Advisor: Peiqing Sun, PhD, Associate Professor, Department of Cell and Molecular Biology

	Peter Sung Keun Lee Recognition of Functionally Conserved Neutralizing Epitopes on Influenza Virus Hemagglutinin Advisor: Ian A. Wilson, PhD, Professor and Chair, Department of Integrative Structural and Computational Biology

	Jeffrey J. Liu Biophysical Investigation of G-protein Coupled Receptor Advisor: Raymond C. Stevens, PhD, Professor, Department of Integrative Structural and Computational Biology

	Dmitry Lyumkis Heterogeneous Macromolecular Machines Analyzed by Single-Particle Electron Advisor: Bridget Carragher, PhD, Professor of Cell Biology, Department of Integrative Structural and Computational Biology

	Denis A. Malyshev Expansion of the Genetic Alphabet in vitro and in vivo Advisor: Floyd E. Romesberg, PhD, Associate Professor, Department of Chemistry

	Christopher E. Martin IL-7 Homeostasis and T Cell Behavior Advisor: Charles D. Surh, PhD, Professor, Department of T Cell Biology, Postech

	Hope Mirendil Lysophosphatidic Acid (LPA) Receptor Signaling is Involved in Schizophrenia Development Initiated by Environmental Risk Factors Advisor: Jerold J.M. Chun, MD, PhD, Professor

	Crystal R. Moran-Gutierrez Advancing Single-Molecule Förster Resonance Energy Transfer Methods to Study Complex Protein Folding Advisor: Ashok A. Deniz, PhD, Associate Professor, Department of Integrative Structural and Computational Biology

	Katerina Otrubova Rational Design of FAAH Inhibitors that Act by Covalently Bonding to Two Active Site Residues Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

	Katherine Lynn Petrie Modeling Evolution In Vitro: Mutagenesis Neutral Drift and Fitness Landscapes Advisor: Gerald F. Joyce, MD, PhD, Professor

	Sanjeev S. Ranade Investigating the Role of Piezo1 a Mechanically Activated Ion channel in Cardiovascular Physiology Advisor: Ardem Patapoutian, PhD, Professor, Department of Molecular and Cellular Neuroscience

	Timothy Reichart Membrane Presentation of Peptides Modulates Neutralizing Antibody Affinity: Implications for HIV Immunogen Design Advisor: Philip E. Dawson, PhD, Associate Dean of Graduate Studies, California; Associate Professor, Department of Cell and Molecular Biology

	Devin Sok Defining Sites of Vulnerability on HIV Env with Diverse Broadly Neutralizing Antibodies to Facilitate Vaccine Design Advisor: Dennis R. Burton, PhD, Professor, Department of Immunology and Microbial Science

	Youngzee Song Understanding the Consequences of Mistranslation Caused by Aminoacyl-tRNA Synthetases Advisor: Paul Schimmel, PhD, Professor, Cell and Molecular Biology

	Sophie B. Sun Elucidating Protein Evolution through Structural Analysis and Expansion of the Genetic Code Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry

	Yun Lei Tan Biological and Chemical Approaches to Enhance Protein Folding and Function Advisor: Jeffery W. Kelly, PhD, Professor and Chair, Department of Molecular and Experimental Medicine

	Luis Miguel Tuesta The Role of Brain Glucagon-Like Peptide-1 in Regulating the Reinforcing Properties of Nicotine Advisor: Paul J. Kenny, PhD, Professor and Chair, Mount Sinai School of Medicine, Department of Pharmacology and Systems Therapeutics

	Chris J. Vickers Activation, Inhibition, and Detection of Caspases Using Chemical Tools Advisor: Dennis W. Wolan, PhD, Assistant Professor, Department of Molecular and Experimental Medicine

	Daniel Wacker Structural Basis of Hallucinogen Signaling through Serotonin and Opioid Receptors Advisor: Raymond C. Stevens, PhD, Professor, Department of Integrative Structural and Computational Biology

	Briana M. Weiser Nipsnap1: A Key Transition Factor in the Hepatitis C Viral Lifecycle Advisor: Timothy L. Tellinghuisen, PhD, Associate Professor, Department of Infectious Diseases

	Amanda L. Wolfe Synthesis and Evaluation of Cyclic seco-CBI-indole2 Prodrugs and Water-Soluble Duocarmycin Analogs Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

	Brady T. Worrell Old Dog New Tricks: Synthetic and Mechanistic Implications of Internal Alkynes in the CuAAC Advisor: Valery V. Fokin, PhD, Associate Professor, Department Chemistry