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Autoimmune Diabetes

Autoimmune diabetes, also known as type-1 diabetes (T1D), is caused by the destruction of insulin-secreting beta-cells in the pancreas by the patient’s own immune system. The non-obese diabetic (NOD) mouse model develops T1D spontaneously and closely resembles the pathology found in human patients. Using Somatic Cell Nuclear Transfer (SCNT or NT), the Kirak lab is at the forefront in developing novel T and B cell mouse model on pure NOD background not only to better understand the development of T1D, but also to find new therapeutic approaches.

...to be continued


Oktay Kirak, MD/PhD
Assistant Professor
The Scripps Research Institute
La Jolla, CA 92037