JANDA LAB

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NEGLECTED TROPICAL DISEASE DIAGNOSTICS & THERAPEUTICS

Shirey RJ, Globisch D, Eubanks LM, Hixon MS, Janda KD. Noninvasive urine biomarker lateral flow immunoassay for monitoring active onchocerciasis. ACS Infect Dis. 2018;4(10):1423-31. PMID: 30141624.

Globisch D, Eubanks LM, Shirey RJ, Pfarr KM, Wanji S, Debrah AY, Hoerauf A, Janda KD. Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG). Bioorg Med Chem Lett. 2017;27(15):3436-40. PMID: 28600214.

Globisch D, Specht S, Pfarr KM, Eubanks LM, Hoerauf A, Janda KD. Litomosoides sigmodontis: A jird urine metabolome study. Bioorg Med Chem Lett. 2015;25(24):5804-7. PMID: 26573416.

Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus molting inhibitors identified through scaffold hopping. ACS Infect Dis. 2015;1(5):198-202. PMID: 27622649.

Gooyit M, Tricoche N, Javor S, Lustigman S, Janda KD. Exploiting the polypharmacology of β-carbolines to disrupt O. volvulus molting. ACS Med Chem Lett. 2015;6(3):339-43. PMID: 25815157.

Globisch D, Moreno AY, Hixon MS, Nunes AA, Denery JR, Specht S, Hoerauf A, Janda KD. Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness. Proc Natl Acad Sci U S A. 2013;110(11):4218-23. PMID: 23440222.

Garner AL, Gloeckner C, Tricoche N, Zakhari JS, Samje M, Cho-Ngwa F, Lustigman S, Janda KD. Design, synthesis, and biological activities of closantel analogues: Structural promiscuity and its impact on Onchocerca volvulus. J Med Chem. 2011;54(11):3963-72. PMID: 21534605.

Li Z, Garner AL, Gloeckner C, Janda KD, Carlow CK. Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy. PLoS Negl Trop Dis. 2011;5(11):e1411. PMID: 22140592.

Denery JR, Nunes AA, Hixon MS, Dickerson TJ, Janda KD. Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis. PLoS Negl Trop Dis. 2010;4(10):e834. PMID: 20957145.

Eubanks LM, Silhar P, Salzameda NT, Zakhari JS, Xiaochuan F, Barbieri JT, Shoemaker CB, Hixon MS, Janda KD. Identification of a natural product antagonist against the botulinum neurotoxin light chain protease. ACS Med Chem Lett. 2010;1(6):268-72. PMID: 20959871.

Gloeckner C, Garner AL, Mersha F, Oksov Y, Tricoche N, Eubanks LM, Lustigman S, Kaufmann GF, Janda KD. Repositioning of an existing drug for the neglected tropical disease onchocerciasis. Proc Natl Acad Sci U S A. 2010;107(8):3424-9. PMID: 20142509.

Park J, Dickerson TJ, Janda KD. Major sperm protein as a diagnostic antigen for onchocerciasis. Bioorg Med Chem. 2008;16(15):7206-9. PMID: 18632276.





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