JANDA LAB

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BIOCHEMICAL REACTIVITY OF DRUGS OF ABUSE

Galinato MH, Lockner JW, Fannon-Pavlich MJ, Sobieraj JC, Staples MC, Somkuwar SS, Ghofranian A, Chaing S, Navarro AI, Joea A, Luikart BW, Janda KD, Heyser C, Koob GF, Mandyam CD. A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse. Mol Psychiatry. 2018;23(3):629-38. PMID: 28348387.

Kimishima A, Wenthur CJ, Zhou B, Janda KD. An advance in prescription opioid vaccines: Overdose mortality reduction and extraordinary alteration of drug half-life. ACS Chem Biol. 2017;12(1):36-40. PMID: 28103678.

Wenthur CJ, Zhou B, Janda KD. Vaccine-driven pharmacodynamic dissection and mitigation of fenethylline psychoactivity. Nature. 2017;548(7668):476-9. PMID: 28813419.

Treweek JB, Roberts AJ, Janda KD. Superadditive effects of ethanol and flunitrazepam: Implications of using immunopharmacotherapy as a therapeutic. Mol Pharm. 2010;7(6):2056-68. PMID: 20849117.

Treweek JB, Dickerson TJ, Janda KD. Drugs of abuse that mediate advanced glycation end product formation: A chemical link to disease pathology. Acc Chem Res. 2009;42(5):659-69. PMID: 19275211.

Brogan AP, Dickerson TJ, Janda KD. Nornicotine-organocatalyzed aqueous reduction of α,β-unsaturated aldehydes. Chem Commun (Camb). 2007;10.1039/b713273e(46):4952-4. PMID: 18361380.

Treweek J, Wee S, Koob GF, Dickerson TJ, Janda KD. Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease. Proc Natl Acad Sci U S A. 2007;104(28):11580-4. PMID: 17592122.

Eubanks LM, Rogers CJ, Beuscher AEt, Koob GF, Olson AJ, Dickerson TJ, Janda KD. A molecular link between the active component of marijuana and Alzheimer's disease pathology. Mol Pharm. 2006;3(6):773-7. PMID: 17140265.

Brogan AP, Dickerson TJ, Boldt GE, Janda KD. Altered retinoid homeostasis catalyzed by a nicotine metabolite: Implications in macular degeneration and normal development. Proc Natl Acad Sci U S A. 2005;102(30):10433-8. PMID: 16014706.

Rogers CJ, Dickerson TJ, Brogan AP, Janda KD. Hammett correlation of nornicotine analogues in the aqueous aldol reaction: Implications for green organocatalysis. J Org Chem. 2005;70(9):3705-8. PMID: 15845010.

Carrera MR, Ashley JA, Hoffman TZ, Isomura S, Wirsching P, Koob GF, Janda KD. Investigations using immunization to attenuate the psychoactive effects of nicotine. Bioorg Med Chem. 2004;12(3):563-70. PMID: 14738965.

Dickerson TJ, Yamamoto N, Ruiz DI, Janda KD. Immunological consequences of methamphetamine protein glycation. J Am Chem Soc. 2004;126(37):11446-7. PMID: 15366884.

Dickerson TJ, Lovell T, Meijler MM, Noodleman L, Janda KD. Nornicotine aqueous aldol reactions: Synthetic and theoretical investigations into the origins of catalysis. J Org Chem. 2004;69(20):6603-9. PMID: 15387581.

Dickerson TJ, Janda KD. Glycation of the amyloid beta-protein by a nicotine metabolite: A fortuitous chemical dynamic between smoking and Alzheimer's disease. Proc Natl Acad Sci U S A. 2003;100(14):8182-7. PMID: 12815102.

Dickerson TJ, Janda KD. A previously undescribed chemical link between smoking and metabolic disease. Proc Natl Acad Sci U S A. 2002;99(23):15084-8. PMID: 12403823.

Gao C, Mao S, Ditzel HJ, Farnaes L, Wirsching P, Lerner RA, Janda KD. A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorg Med Chem. 2002;10(12):4057-65. PMID: 12413859.

Isomura S, Hoffman TZ, Wirsching P, Janda KD. Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration. J Am Chem Soc. 2002;124(14):3661-8. PMID: 11929256.

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