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The Wüthrich Laboratory

Current Positions: Cecil H. and Ida M. Green Professor of Structural Biology, The Scripps Research Institute, La Jolla, CA, USA.; Professor of Biophysics, ETH Zürich, Zürich, Switzerland.

Personal Data

Born October 4, 1938, in Aarberg, Switzerland. Swiss citizen.
Married to Marianne Briner, 1963; two children, Bernhard Andrew 1968, Karin Lynn 1970.

Education and Positions Held

1957–62

University of Bern, Switzerland:   Lizentiat in chemistry, physics and mathematics.

1962–64

University of Basel, Switzerland: Ph.D. in   chemistry (Prof. S. Fallab); Eidgenössisches Turn- und Sportlehrerdiplom.

1964–65

University of Basel, Switzerland:   Postdoctoral training (Prof. S. Fallab).

1965–67

University of California, Berkeley,    CA, USA   : Postdoctoral training (Prof. R.E. Connick).

1967–69

Bell Telephone   Laboratories, Murray Hill,    N.J., USA   : Member Technical Staff, Biophysics Department (Dr. R.G. Shulman).

1969–

ETH Zurich,   Zurich, Switzerland: Privatdozent (70),   Assistant Professor (72), Associate Professor (76), Professor of Biophysics   (80); Chairman Biology Department (95–2000).

2001–04

The Scripps Research Institute, La Jolla, CA,    USA: Cecil H.   and Ida M. Green Visiting Professor of Structural Biology.

2004–

The Scripps Research Institute, La Jolla, CA,    USA: Cecil H.   and Ida M. Green Professor of Structural Biology.

Major Research Interests

Biology, structure and function of proteins and nucleic acids; development of nuclear magnetic resonance (NMR) techniques for macromolecular structure determination in solution and for studies of intermolecular interactions; applications in structural genomics, proteomics and biomedical research.

Publications

NMR in Biological Research: Peptides and Proteins, North-Holland, Amsterdam, 1976.

NMR of Proteins and Nucleic Acids, Wiley, New York, 1986.

NMR in Structural Biologya Collection of Papers by Kurt Wüthrich, World Scientific, Singapore, 1995.

790 original papers and reviews.

Visiting Faculty Appointments

1988

November: Visiting Miller Research   Professor, University of California, Berkeley,    CA, USA.

1992

February–March: Scholar in   Residence, Johns Hopkins University,   Baltimore, MD, USA.

1994

February–June: Sherman   Fairchild Distinguished Scholar, Caltech, Pasadena, CA, USA.

1994

October–December: Guest Scientist,   The Scripps Research Institute, La     Jolla, CA, USA.

1995

February–April: Visiting Associate   in Biology and Chemistry, Caltech, Pasadena,    CA, USA.

1997–98

For two months: Institute of Physical   and Chemical Research (RIKEN), Tokyo,    Japan.

1997–00

Visiting Professor, Dept. of   Chemistry, University of Edinburgh, Edinburgh,    UK.

2004–

Honorary Professor, Dalian   Institute of Chemical Physics, Chinese Academy     of Sciences, China.

2004–

Honorary Professor, Dalian   Institute of Light Industry, Dalian,    China.

2006–08

Underwood International College   Distinguished Professor, Yonsei University, Seoul,    Korea.

2006–

Honorary Professor of Science,   Chinese University of Hong Kong, Hong Kong.  

2009–13

WCU Distinguished Professor,   Yonsei University, Seoul, Korea.

2011–

Honorary Visiting Professor,   Universität Duisburg–Essen, Germany.

2012–

Honorary Distinguished Professor,   Tumkur University, Tumkur, Karnataka, India.

2012–16

Pesquisador Visitante Especial,   Universidade Federal do Rio de Janeiro, Brazil.

2013–

Distinguished Senior Professor,   iHuman Institute, ShanghaiTech University, Shanghai, China.

2014–

Adjunct Distinguished Professor,   Daegu Gyeongbuk Institute of Science and Technology. (DGIST), Daegu, Korea.

Awards

1974

Friedrich-Miescher-Preis,   Schweizerische Gesellschaft für Biochemie.

1983

Shield of the Faculty of Medicine,   Tokyo University, Japan.

1986

Médaille P. Bruylants, Université Catholique de Louvain, Belgium.

1990

Stein and Moore   Award of the Protein Society,    USA.

1991

Louisa Gross Horwitz Prize, Columbia University, New York, USA.

1991

Gilbert Newton   Lewis Medal, University of California, Berkeley,    USA.

1992

Marcel Benoist-Preis, awarded by   the Swiss Confederation.

1993

Distinguished Service Award, The Miami Bio/Technology Winter Symposia, USA.

1993

Prix Louis Jeantet de Médecine,   Fondation Louis Jeantet, Geneva,    Switzerland.

1996

Kaj Linderstrøm-Lang Prize,   Carlsberg Foundation, Copenhagen,    Denmark.

1997

Eminent Scientist of RIKEN, Tokyo, Japan.

1998

Kyoto Prize in   Advanced Technology, Inamori Foundation, Kyoto, Japan.

1999

Günther Laukien Prize,   Experimental NMR Conference (ENC), USA.

1999

Otto-Warburg-Medaille,   Gesellschaft für Biochemie und Molekularbiologie,    Germany.

2001

Médaille d‘Honneur en Argent,   Société d‘Encouragement au Progrès, Paris,    France.

2002

Nobel Prize in Chemistry.

2002

World ‘Future’ Award, The World   Awards, Wien, Austria.

2002

Swiss ‘Society’ Award, The Swiss   Awards, Zürich, Switzerland.

2002

Ehrenpreis 2002, City of Wallisellen, Switzerland.

2003

Honorary Citizenship, City of Lyss, Switzerland.

2008

Johannes M. Bijvoet Medal, Utrecht University,   Utrecht, The Netherlands.

2008

Paul Walden Medal, Riga Technical   University, Riga, Latvia.

2009

Jabir ibn Hyyan (Geber) Medal,   Saudi Chemical Society, Saudi Arabia.

2010

Ralph and Helen Oesper Award,   University of Cincinnati, Cincinnati, OH, USA.

2012

President’s Gold Medal, Government   of India.

2013

Theodor Bücher Medal, Federation   of European Biochemical Societies.

2015

IUBMB Medal

2016

Shanghai 1,000 Talents Award.

2017

 Genome Valley Excellence Award, BioAsia, Hyderbad, India

2017

Shanghai International Science and Technology Cooperation Award, Shanghai, China

Honorary Degrees

1997

Dottore ad Honorem in Chimica, Università degli Studi di Siena, Italy.

1997

Dr. phil. honoris causa, Universität Zürich, Switzerland.

2001

Docteur   honoris causa, Ecole Polytechnique Fédérale de Lausanne, Switzerland.

2004

Doctor honoris   causa, Universitat de València,    Spain.

2004

Doctor of   Science honoris causa, University of     Sheffield, UK.

2004

Profesor Extraordinario con   distinción de Académico Ilustre, U.N. Mar del Plata, Argentina.

2005

Doctor of Science honoris causa, King George’s Medical University,   Lucknow, India.

2007

Doctor of Medicine honoris causa, University of Pécs, Hungary.

2007

Doctor of Chemistry honoris causa, Universidad del Norte,   Asunción, Paraguay.

2007

Doctor honoris causa, Lomonosov   Moscow State   University, Moscow, Russia.

2007

Laurea Specialistica in Biotechnology honoris causa, University of Verona, Italy.

2007

Docteur honoris causa, Université René Descartes, Paris,   France.

2012

Laurea   Magistrale in Pharmacology honoris causa, Università degli Studi di Napoli,   Italy.

2015

Doctor honoris causa in   Phamacology, University of Patras, Greece.

2015

Doctor honoris causa, Universidad de Buenos Aires,   Argentina.

2015

Severo Ochoa Lecture, 23rd   IUBMB Congress, Foz do Iguaçu, Brazil.

2016

Doctor honoris causa,   Universidad Nacional de Córdoba, Argentina.

Academies and Honorary Memberships in Societies

1984

European Molecular Biology   Organization (EMBO).

1987

Deutsche Akademie der   Naturforscher Leopoldina.

1989

Academia Europaea.

1989

Foreign Fellow, Indian National    Science Academy.

1992

Foreign Associate,   US National Academy   of Sciences.

1992

Honorary Fellow, The National Academy of Sciences, India.

1993

Foreign Honorary Member, American Academy of Arts and Sciences.

1993

Honorary Member, Japanese   Biochemical Society.

1998

Honorary Member, National Magnetic   Resonance Society of India.

1998

AAAS Fellow, American Association   for the Advancement of Science.

2000

Associé étranger, Académie des   Sciences, Institut de France.

2001

Schweizerische Akademie der   Technischen Wissenschaften (SATW).

2002

Schweizerische Akademie der   Medizinischen Wissenschaften (SAMW).

2002

IUPAC Fellow.

2003

Honorary Fellow, The Royal Society   of Chemistry, UK (HonFRSC).

2003

Honorary Fellow, The Royal Society   of Edinburgh, UK (HonFRSE).

2003

Honorary Member, Swiss Chemical   Society.

2003

Honorary Member, Wallisellen   Football Club, Switzerland.

2003

Titular Member, European Academy   of Arts, Sciences and Humanities.

2004

Honorary Member, International   Society for Magnetic Resonance in Medicine.

2004

Honorary Member, Hungarian Academy   of Sciences.

2004

Honorary Member, World Academy   of Young Scientists.

2004

Honorary Member, World High   Technology Society, Dalian,    China.

2004

Honorary Member, European Academy   of Sciences and Arts.

2004

Foreign Member, Latvian Academy   of Sciences.

2004

Honorary Member, Groupement   Ampère.

2004

Honorary Member, The Nuclear   Magnetic Resonance Society of Japan.

2005

Honorary Member, Indian Biophysical   Society.

2005

Corresponding Member,   Nordrhein-Westfälische Akademie der Wissenschaften.

2005

Foreign Member, The Korean Academy of Science and Technology.

2005

Honorary Member, The Korean   Magnetic Resonance Society.

2008

Honorary Fellow, Latvian Institute   of Organic Synthesis, Riga,    Latvia.

2008

ISMAR Fellow.

2010

Foreign Member, The Royal Society,   UK (ForMem RS).

2012

Honorary Fellow, The Spanish   Biophysical Society.

2013

Corresponding Member, Academia   Brasileira de Ciências.

2017

JMR Fellow, Journal of Magnetic   Resonance, USA.

Named Lectures

1982

FMC Lectures, Princeton University,   Princeton, NJ, USA.

1983

Baker Lectures, Cornell University,   Ithaca, NY,    USA.

1984

S. Rudin Lecture, Columbia    University Medical School, New York,   NY, USA.

1986

Chaire Bruylants, Université   Catholique de Louvain, Louvain-La-Neuve,    Belgium.

1989

James Shannon Lecture, Massachusetts General Hospital,   Boston, MA,    USA.

1989

Ada Doisy   Lectures, University of Illinois, Urbana,    IL, USA.

1990

Pittsburgh   Conference Lectures, University of Pittsburgh, Pittsburgh,    PA, USA.

1991

Distinguished Lecture in   Structural Biology, Dartmouth College, Hannover,    NH, USA.

1991

John T. Edsall Lecture, Harvard University,   Cambridge, MA, USA.

1991

Ira Remsen Memorial Lecture, Johns Hopkins   University, Baltimore, MD, USA.

1993

William H. Stein Memorial Lecture,   Rockefeller University, New York,    NY, USA.

1993

Calbiochem Lectures, UCSD, San Diego, CA,    USA.

1993

Martinsrieder Kolloquium, MPI für   Biochemie, Martinsried, Germany.

1995

P.A. Leermakers Lecture, Wesleyan University,   Middletown, CT, USA.

1995

Adam Neville Lecture, University of Dundee,   Dundee, UK.

1996

UCLA-DOE Distinguished Lecture,   UCLA, Los Angeles, CA, USA.

1997

UMDNJ Distinguished Lecture, Rutgers University,   Piscataway, NJ, USA.

1998

University Lecture, University of Texas   Southwestern Medical Center, Dallas,    TX, USA.

1998

Ames Lecture,   Dept. of Chemistry, University of Edinburgh, Edinburgh,    UK.

2000

Gitte Vold Memorial Lecture, UCSD,   San Diego, CA, USA.

2001

Peter Hemmerich-Vorlesung,   Universität Konstanz, Konstanz,    Germany.

2002

Merck   Frosst Lectures, Dept.of Chemistry, Simon   Fraser University,   Vancouver, BC, Canada.

2002

Harry   Steenbock Lectures in Biochemistry, University   of Wisconsin, Madison, WI, USA.

2003

Eraldo   Antonini Memorial Lecture, Unversità di    Roma “La Sapienza”, Rome,    Italy.

2004

Faculty   Lecture Series, The Scripps Research Institute, La Jolla, CA, USA.

2004

Eyring   Lectures, Arizona State University,   Tempe, AZ,    USA.

2004

Robbins   Lectures, Pomona College, Claremont,    CA, USA.

2004

Stammbach   Lecture, Swiss Society of Neuropathology, St. Moritz, Switzerland.

2004

Derby Lectures, Department of Chemistry, University of Louisville,   Louisville, KY, USA.

2004

Lauterbur   Lecture, ISMRM Twelfth Scientific Meeting and Exhibition, Kyoto, Japan.

2004

Ernst-Abbe-Kolloquium,   Friedrich-Schiller-Universität, Jena,    Germany.

2004

Datta   Lecture, 29th FEBS Congress, Warsaw,    Poland.

2005

Trombay   Colloquium, Bhabba Atomie Research Centre, Mumbai, India.

2005

Sarojini   Damodoran Lecture, Tata Institute of Fundamental Research, Mumbai, India.

2005

G.N.   Ramachandran Memorial Lecture, Indian Biophysical Society, Pune, India.

2007

Irving L.   Schwartz Lecture, Mount Sinai School of Medicine, New York, NY, USA.

2007

Aline U.   and James M. Orten Memorial Lecture, Wayne   State University,   Detroit, MI, USA.

2007

Philip   Handler Lecture, Duke University Medical   Center, Durham, NC, USA.

2008

Discovery   Lecture, Vanderbilt University Medical   Center, Nashville, TN, USA.

2009

V.   Ramalingaswami Memorial Lecture, National Institute of Immunology, New Delhi, India.

2009

IUBMB Life   Lecture, 21st IUBMB International Congress, Shanghai, China.

2010

Luigi Sacconi Memorial Lecture,   Università degli Studi di Firenze, Firenze, Italy.

2011

Cannizzaro   Lecture, Società Chimica Italiana, Italy.

2013

Bücher   Lecture, 38th FEBS Congress, St. Petersburg, Russia.

2015

Severo   Ochoa Lecture, 23rd IUBMB Congress, Foz do Iguaçu, Brazil.

2016

ShanghaiTech   Lecture, SIAIS BioForum, Shanghai, China.

 2017

 Endel Lippmaa Memorial Lecture, Estonian Academy of Sciences, Tallinn, Estonia.

 2017

 Eraldo Antonini Lecture, 59th SIB Congress, Caserta, Italy.

Scientific Advisory Boards
Centro Stefano Franscini, Monte Verità and ETH Zürich, Switzerland, 89–98.
European Molecular Biology Laboratory, Heidelberg, Germany, 89–95.
National Laboratory of Biomacromolecules, Academia Sinica, Beijing, China, 89– 04.
Deutsche Forschungsgemeinschaft, Bonn, Germany: Schwerpunktsprogramm “Protein Design”, 89–95.
Commission of the European Communities: Human Capital and Mobility Program, 92–94.
Institut für Molekulare Biotechnologie, Jena, Germany, 93–96.
Ciba Foundation, London, UK, 94–96.
Institut de Biologie Structurale Jean-Pierre Ebel, Grenoble, France, 94–97.
Institute of Biotechnology, University of Helsinki, Finland, 97–05.
Novartis Foundation, London, UK, 97– 05.
Triad Therapeutics Inc., La Jolla, CA, USA, 98– 04.
Genomics Sciences Center, RIKEN, Tokyo, Japan, 00–05.
Syrrx Inc., La Jolla, CA, USA, 00–04.
Groupement d‘Intérêt Scientifique “Infections à Prions”, France, 01–05.
National Institute of Chemical Physics and Biophysics (NICPB), Tallinn, Estonia, 01–05.
National High Field NMR Center (NANUC), University of Alberta, Edmonton, AB, Canada, 01–04.
Resource for Solid-State NMR of Proteins at UCSD, La   Jolla, CA, USA, 01–04.
Eidogen-Sertanty, Inc., San Diego, CA, USA 02–.
Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, 05–.
Solvay Scientific Committee for Chemistry, International Solvay Institutes, Brussels, Belgium.
Member 05–11; Chairman 11–.
Honorary Advisory Board of IUBMB, 07–.
Councillor of the Foundation Antidoping Switzerland, 08–10.
Scientific Advisory Board, Department of Biosciences and Bioengineering, IIT Indore, India, 12–.
Academic Advisory Board, Beijing Advanced Innovation Center for Structural Biology (ICSB), China, 17–.

Editorial Assignments

Editor: Q. Rev.Biophys. 84–91, 96–01; Macromolecular Structures 90–00; J. Biomol. NMR 91–11.
Member Editorial Board: Advanced Science Letters; Biochim. Biophys. Acta, Biochimie, Biology, Biophys. Chem., Biopolymers, CHEMBIOCHEM, Chemtracts, Chemical Physics Letters, Encyclopedia of NMR, Comm. Mol. Cell. Biophysics, Curr. Methods Mol. Cell Biol., Curr. Opinion Struct. Biol., Eur. Biophys. J., Inorg. Chim. Acta, Israel J. Chem., IUBMB Life, J. Biotechnology, J. Computer-Aided Mol. Design, J. Magn. Reson., J. Membrane Biol., J. Struct. Funct. Genomics, Life Sciences, PeerJ, Proteins, Structure, The Natural Products Journal.

Consultancy Assignments

Hoechst AG, Frankfurt, Germany, 85–92.
Sandoz Pharma AG, Basel, Switzerland, 87–96.
Hoffmann-La Roche AG, Basel, Switzerland, 87– 04.
Ciba-Geigy AG, Basel, Switzerland, 89–96.
Tripos Inc., St. Louis, MO, USA, 92–94.
Novartis AG, Basel, Switzerland, 97–.

Offices in Professional Organizations

Schweiz. Kommission für Molekularbiologie (SKMB): Member 73–76; President 77–82.
International Union of Pure and Applied Biophysics (IUPAB): Council Member 75–78 and 87–90; Secretary General 78–84; Vice-President 84–87.
International Council of Scientific Unions (ICSU): Member General Committee 80–86; Member Standing Committee on the Free Circulation of Scientists 82–90.
Kommission für die Wolfgang Pauli-Vorlesungen, ETH Zürich: Member 84–92; President 93–01.
Zürcher Chemische Gesellschaft: President 90–91.
Schweiz. Gesellschaft für Biochemie: Member Executive Committee 86–92; President Biophysics Section 85–88.
International Union of Pure and Applied Chemistry (IUPAC), Commission on Biophysical Chemistry: Member 96–99; Chairman 00–01.
Prix Marcel Benoist, Conseil de Fondation, Bern: Member 01–15.

Patronage Committees

Visionen ETH 2030, 150th Anniversary ETH Zürich, Switzerland, 03–05.
International Jury, World Awards, Vienna, Austria, 03–07.
Honorary Board, The International Wallenberg   Foundation, New York, USA, 03–.
Academy Member, Swiss Awards, Zürich, Switzerland, 03–15.
2. Schweizerische Kunstturntage, Bern, Switzerland 2004, 03–04.
Symposium Systems Biology (C-BSSE), Basel, Switzerland 2004, 03–04.
Kulturprojekt “Einstein05”, Bern, Switzerland 2005, 04–05.
Buchlobby Schweiz, Switzerland, 04–.
Science et Cité, Bern, Switzerland, 04–11.
Synapsis Foundation, Zürich, Switzerland, 04–.
Honorary Board, Swiss Science Forum, 05–.
International Peace Foundation, 05–.
Founder’s Assembly of the Foundation Lindau Nobel Prize Winners Meetings, 05–.
Association of Swiss Scientific Olympiads, 05–.
Ambassador for Zürich, UEFA EURO 2008, 06–08.
175th Anniversary University of Zürich, Switzerland 2008, 07–08.
European Gymnastics Championships, Bern, Switzerland, 2016 14–16.
Anniversary “50 Jahre Schweizer Jugend forscht”, 16–.