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The Felding Laboratory


Santidrian AF, Matsuno-Yagi A, Ritland M, Seo BB, LeBoeuf SE, Gay LJ, Yagi T, Felding-Habermann B. (2013) Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression. J Clin Invest [E-pub Feb 15, 2013] PMID: 23426180

Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, Pinkstaff JK, Tian F, Sinha SC, Felding-Habermann B, Smider VV, Schultz PG (2012) Proc Natl Acad Sci USA 109(40): 16101-6. PMID: 22988081

Lorger M, Felding-Habermann B (2012) Integrin Signaling in angiogenesis and metastatic progression to the brain. Chapter 13 in “Signaling Pathways and Molecular Mediators in Metastasis” S. Fatatis (ed), Springer Science and Business Media

Gay LJ, Felding-Habermann B (2011) Platelets alter tumor cell attributes to propel metastasis: programming in transit. Cancer Cell 20(5): 553-554. PMID: 22094248

Lorger M, Lee H, Forsyth JS, Felding-Habermann B (2011) Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells. J Neurooncol 104(3): 686-96. PMID: 21359851

Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Schultz PG, Smider VV (2011) Site-specific coupling and sterically controlled formation of multimeric antibody Fab fragments using unnatural amino acids. J Mol Biol 406 (4): 595-603. PMID: 21237172

Hutchins BM, Kazane SM, Staflin K, Forsyth JS, Felding-Habermann B, Smider VV, Schultz PG (2011) Selective Formation of Covalent Protein Heterodimers with a Non-natural Amino Acid. Chem Biol 18(3): 299-303. PMID: 21439474

Gay LJ, Felding-Habemann B (2011) Contribution of platelets to tumor metastasis. Nat Rev Cancer 11(2): 123-34. PMID: 21258396

Felding-Habermann B, Gay LJ (2010) Platelets at the intersection of hemostasis, inflammation, and tumor metastasis. Proceedings of the Society of Toxicologic Pathology, STP/IFSTP Joint Symposium Report

Staflin K, Krueger JS, Hachmann J, Lorger M, Forsyth JS, Steiniger SCJ, Mee J, Pop C, Salvesen G, Janda KD, Felding-Habermann B (2010) Targeting activated integrin avb3 with patient derived antibodies impacts late-stage multiorgan metastasis. Clin Exp Metastasis 27(4):217-31. PMID: 20225083

Lorger M, Felding-Habermann B (2010) Capturing changes in the brain microenvironment during initial steps of brain metastasis. Am J Pathol 176(6):2958-71. PMID: 20382702

Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang C, Zhang J, Natu VS, Lairson LL, Walker JR, Trussel CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, Miraglia LJ, Rines DR, Skirball SL, Schultz PG (2010) An RNAi screen identified TRRAP as a regulator of brain tumor-initiating cell differentiation. Cell Stem Cell Jan 8;6(1):37-47. PMID: 20085741

Goswami RK, Haung ZZ, Forsyth JS, Felding-Habermann B, Sinha SC (2009) Multiple catalytic aldolase antibodies suitable for chemical programming. Bioorg Med Chem Lett 19(14):3821-24. PMID: 19428247

Katz J, Krueger JS, Felding-Habermann B, Snyder EY (2009) Maintaining and engineering neural stem cells for delivery of genetically encoded therapy to brain tumors. Meth Mol Biol 568:249-59. PMID: 19582432

Lorger M, Krueger JS, O’Neal M, Staflin K, Felding-Habermann B (2009) Activation of tumor cell integrin avb3 controls angiogenesis and metastatic growth in the brain. Proc Natl Acad Sci USA 106(26): 10666-71. PMID: 19541645

Versteeg HH, Schaffner F, Kerver M, Petersen HH, Ahamed J, Felding-Habermann B, Takada Y, Mueller BM, and Ruf W (2008) Inhibition of tissue factor signaling suppresses tumor growth. Blood 111(1):190-9. PMID: 17901245

Jain S, Zuka M, Liu J, Russell S, Dent J, Guerrero JA, Forsyth J, Maruszak B, Gartner TK, Felding-Habermann B, and Ware J. (2007) Platelet glycoprotein Iba supports experimental lung metastasis. Proc Natl Acad Sci USA 104(21): 9024-8. PMID: 17494758

Liu Y, Steiniger SC, Kim Y, Kaufmann GF, Felding-Habermann B, Janda KD (2007) Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery. Mol Pharm. 4(3):435-47. PMID: 17373820

Palmieri D, Chambers AF, Felding-Habermann B, Huang S, Steeg PS (2007) The biology of metastasis to a sanctuary site. Clin Cancer Res 13(6): 1656-1662. PMID: 17363518

Chen EI, Hewel J, Krueger JS, Weber MR, Tiraby C, Kralli A, Becker K, Yates JR III, Felding-Habermann B. (2007) Adaptation of energy metabolism in breast cancer brain metastases. Cancer Res 67(4): 1472-1486. PMID: 17308085

Earlier Key Paper

Felding-Habermann, B., Lerner, R.A., Lillo, A., Zhuang, S., Weber, M.R., Arrues, S., Gao, C., Mao, S., Saven, A., Janda, K.D. (2004) Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proc Natl Acad Sci USA 101: 17210-17215.PMID: 15563590

Rolli M, Fransvea E, Pilch J, Saven A, Felding-Habermann B (2003) Activated integrin αvβ3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells. Proc Natl Acad Sci USA 100(16): 9482-9487. PMID: 12874388

Felding‑Habermann B, O'Toole TE, Smith JW, Fransvea E, Ruggeri ZM, Ginsberg MH, Hughes PE, Pampori N, Shattil SJ, Saven A, Mueller BM (2001) Integrin activation controls metastasis in human breast cancer. Proc Natl Acad Sci U S A 98(4):1853‑1858. PMID: 11172040




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