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The Teyton Laboratory

Publications

  1. Freymuth F, Langeard MM, Daon F, Teyton L, Guihard P, L'Hirondel L, Venezia R. Infections à virus respiratoire syncitial. Revue Institut Pasteur de Lyon 13:111 (1980).
  2. Teyton L. Traitement des brucelloses ostéo-articulaires. NPM Médecine 10:729 (1981).
  3. Mora JJ, Teyton L, Souquières G, L'Hirondel JL, Loyau G. Métastase synoviale révélatrice d'un adénocarcinome. Rhumatologie 34:499 (1982).
  4. Teyton L, Loyau G, Freymuth F. Polyarthrite rhumatoide : le point sur sa pathogénie, le rôle possible du virus d'Epstein-Barr. Revue de Médecine 24:13 (1983).
  5. Guaydier-Souquières G, Teyton L, Loyau G, L'Hirondel JL. Métastase synoviale révélatrice d'un adénocarcinome. LARC Médical 3:300 (1983).
  6. Mora JJ, Teyton L, Loyau G, Ollivier D. [Tuberculosis complicating the course of acute systemic lupus erythematosus]. LARC Med 3:417-418 (1983). PMID: 6888110.
  7. Teyton L, Mora JJL, G. Scanner et bilan d'un abcès pottique. LARC Med 3:309 (1983).
  8. Teyton L, Mora JJ, Loyau G, Mahoudeau J, L'Hirondel JL, Lebrun E, Dumas M, Ollivier D. [Cleidocranial dysostosis. Contribution to its study a propos of 2 personal cases (an isolated and a familial form)]. Rev Med Interne 5:76-82 (1984). PMID: 6718841.
  9. Teyton L, Pouletty P. Le lupus érythémateux disséminé : physiopathologie, diagnostic, évolution et pronostic. Concours Médical 107:3311 (1985).
  10. Teyton L, Lotteau V, Boyer B, Charron DJ. 1985. A quantitative dot immunobinding assay for human HLA class II antigens (Abstract). Conférence Européenne d'Histocompatibilité.
  11. Charron DJ, Teyton L. Fonction de la région HLA-D. In 5éme Cours d'Immunorhumatologie de Montpellier. Sany and Clot, editors (1985).
  12. Teyton L, Lotteau V, Pulol JP, Loyau G, Charron DJ. HLA class II antigen expression in synovial lining cells from rheumatoid arthritis patients. Human Immunol. 14:135 (1985).
  13. Charron DJ, Teyton L, Lotteau V, Merlu B, Néel D, Haziot A. Anti-Ia antibodies in the treatment of autoimmune diseases. In Molecular diversity of the human Ia system. Academic Press (1986).
  14. Teyton L, Lotteau V, Boyer B, Charron DJ. A quantitative dot immunobinding assay for human HLA class II antigens using nitrocellulose membrane filters. J Immunol Methods 89:73-79 (1986).PMID: 3517174.
  15. Charron DJ, Lotteau V, Haziot A, Teyton L. Techniques biochimiques d'analyse des antigènes de membrane. INSERM (1987).
  16. Arenzana-Seisdedos F, Teyton L, Virelizier JL. Immunoregulatory mediators in the pathogenesis of rheumatoid arthritis. Scand J Rheumatol Suppl 66:13-17 (1987). PMID: 3131870.
  17. Charron D, Teyton L. AutoImmunity in rheumatoid arthritis. A qualitative and quantitative approach to the role of Ia antigens. Concepts Immunopathol 4:200-214 (1987). PMID: 3297335.
  18. Teyton L, Lotteau V, Brandely M, Turmel P, Viguier M, Pujol., Loyau G, Charron DJ. Effects of cyclosporin A on IFNg induction of Ia antigens on adherent synovial lining cells. In Clinical Immunol. P. W. and S. M., editors (1987).
  19. Teyton L, Lotteau V, Turmel P, Arenzana-Seisdedos F, Virelizier JL, Pujol JP, Loyau G, Piatier-Tonneau D, Auffray C, Charron DJ. HLA DR, DQ, and DP antigen expression in rheumatoid synovial cells: a biochemical and quantitative study. J Immunol 138:1730-1738 (1987). PMID: 3102596.
  20. Lotteau V, Teyton L, Tongio MM, Soulier A, Thomsen M, Sasportes M, Charron D. Biochemical polymorphism of the HLA-DP heavy chain. Immunogenetics 25:403-407 (1987). PMID: 3596675.
  21. Lotteau V, Teyton L, Burroughs D, Charron D. A novel HLA class II molecule (DR alpha-DQ beta) created by mismatched isotype pairing. Nature 329:339-341 (1987). PMID: 3306409.
  22. Mauviel A, Teyton L, Bhatnagar R, Penfornis H, Laurent M, Hartmann D, Bonaventure J, Loyau G, Saklatvala J, Pujol JP. Interleukin-1 alpha modulates collagen gene expression in cultured synovial cells. Biochem J 252:247-255 (1988). PMID: 2844146.
  23. Lotteau V, Sands J, Teyton L, Turmel P, Charron D, Strominger JL. Modulation of HLA class II antigen expression by transfection of sense and antisense DR alpha cDNA. J Exp Med 169:351-356 (1989). PMID: 2462612.
  24. Lotteau V, Teyton L, Peleraux A, Nilsson T, Karlsson L, Schmid SL, Quaranta V, Peterson PA. Intracellular transport of class II MHC molecules directed by invariant chain. Nature 348:600-605 (1990). PMID: 2250716.
  25. Teyton L, O'Sullivan D, Dickson PW, Lotteau V, Sette A, Fink P, Peterson PA. Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways. Nature 348:39-44 (1990). PMID: 2234057.
  26. Temime N, Joliviere A, Lando D, Teyton L, Charron D. Autocrine stimulation of interleukin 1 in human adherent synovial lining cells: down regulation by interferon gamma. Hum Immunol 31:261-270 (1991). PMID: 1917593.
  27. Teyton L, Peterson PA. Assembly and transport of MHC class II molecules. New Biol 4:441-447 (1992). PMID: 1515409.
  28. Teyton L, Peterson PA. Invariant chain--a regulator of antigen presentation. Trends Cell Biol 2:52-56 (1992). PMID: 14731527.
  29. Teyton L. Assembly and transport of major histocompatibility complex molecules. Nouv Rev Fr Hematol 36 Suppl 1:S33-36 (1994). PMID: 7909942.
  30. Pond L, Kuhn LA, Teyton L, Schutze MP, Tainer JA, Jackson MR, Peterson PA. A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway. J Biol Chem 270:19989-19997 (1995). PMID: 7650016.
  31. Jackson MR, Fruh K, Karlsson L, Teyton L, Yang Y, Peterson PA. Assembly and intracellular transport of MHC class I and class II molecules. Cold Spring Harb Symp Quant Biol 60:249-261 (1995). PMID: 8824398.
  32. Eastman S, Deftos M, DeRoos PC, Hsu DH, Teyton L, Braunstein NS, Hackett CJ, Rudensky A. A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody. Eur J Immunol 26:385-393 (1996). PMID: 8617308.
  33. Scott CA, Garcia KC, Carbone FR, Wilson IA, Teyton L. Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules. J Exp Med 183:2087-2095 (1996). PMID: 8642319
  34. Huang JF, Teyton L, Harper JF. Activation of a Ca(2+)-dependent protein kinase involves intramolecular binding of a calmodulin-like regulatory domain. Biochemistry 35:13222-13230 (1996). PMID: 8855961.
  35. Garcia KC, Scott CA, Brunmark A, Carbone FR, Peterson PA, Wilson IA, Teyton L. CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature 384:577-581 (1996). PMID: 8955273.
  36. Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA. An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274:209-219 (1996). PMID: 8824178.
  37. Wilson IA, Garcia KC, Degano M, Stanfield RL, Zeng Z, Segelke B, Stura EA, Castano AR, Jewell DA, Brunmark A, Jackson MR, Peterson PA, Teyton L. 1996. Structural Basis of Cellular Immune Recognition. Proceedings of Copenhagen Meetings.
  38. Lang J, Jackson M, Teyton L, Brunmark A, Kane K, Nemazee D. B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen. J Exp Med 184:1685-1697 (1996). PMID: 8920858.
  39. Garcia KC, Degano M, Stanfield RL, Scott C, Brunmark A, Peterson PA, Wilson IA, Teyton L. Structural Basis of T cell Recognition. Vaccine C.S.H. Editions (1997).
  40. Garcia KC, Tallquist MD, Pease LR, Brunmark A, Scott CA, Degano M, Stura EA, Peterson PA, Wilson IA, Teyton L. Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization. Proc Natl Acad Sci U S A 94:13838-13843 (1997). PMID: 9391114.
  41. Aichinger G, Karlsson L, Jackson MR, Vestberg M, Vaughan JH, Teyton L, Lechler RI, Peterson PA. Major histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins. J Biol Chem 272:29127-29136 (1997). PMID: 9360989.
  42. Cai Z, Brunmark AB, Luxembourg AT, Garcia KC, Degano M, Teyton L, Wilson I, Peterson PA, Sprent J, Jackson MR. Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells. Immunol Rev 165:249-265 (1998). PMID: 9850865.
  43. Scott CA, Garcia KC, Stura EA, Peterson PA, Wilson IA, Teyton L. Engineering protein for X-ray crystallography: the murine Major Histocompatibility Complex class II molecule I-Ad. Protein Sci 7:413-418 (1998). PMID: 9521118.
  44. Luxembourg AT, Borrow P, Teyton L, Brunmark AB, Peterson PA, Jackson MR. Biomagnetic isolation of antigen-specific CD8+ T cells usable in immunotherapy. Nat Biotechnol 16:281-285 (1998). PMID: 9528010.
  45. Liljedahl M, Winqvist O, Surh CD, Wong P, Ngo K, Teyton L, Peterson PA, Brunmark A, Rudensky AY, Fung-Leung WP, Karlsson L. Altered antigen presentation in mice lacking H2-O. Immunity 8:233-243 (1998). PMID: 9492004.
  46. Scott CA, Peterson PA, Teyton L, Wilson IA. Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity 8:319-329 (1998). PMID: 9529149.
  47. Garcia KC, Degano M, Pease LR, Huang M, Peterson PA, Teyton L, Wilson IA. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science 279:1166-1172 (1998). PMID: 9469799.
  48. Manning TC, Schlueter CJ, Brodnicki TC, Parke EA, Speir JA, Garcia KC, Teyton L, Wilson IA, Kranz DM. Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition. Immunity 8:413-425 (1998). PMID: 9586632.
  49. Speir JA, Garcia KC, Brunmark A, Degano M, Peterson PA, Teyton L, Wilson IA. Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes. Immunity 8:553-562 (1998). PMID: 9620676.
  50. Garcia KC, Teyton L. T-cell receptor peptide-MHC interactions: biological lessons from structural studies. Curr Opin Biotechnol 9:338-343 (1998). PMID: 9720260.
  51. Garcia KC, Teyton L, Wilson IA. Structural basis of T cell recognition. Annu Rev Immunol 17:369-397 (1999). PMID: 10358763.
  52. Manning TC, Parke EA, Teyton L, Kranz DM. Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing. J Exp Med 189:461-470 (1999). PMID: 9927508.
  53. Celia H, Wilson-Kubalek E, Milligan RA, Teyton L. Structure and function of a membrane-bound murine MHC class I molecule. Proc Natl Acad Sci U S A 96:5634-5639 (1999). PMID: 10318936.
  54. Kieke MC, Shusta EV, Boder ET, Teyton L, Wittrup KD, Kranz DM. Selection of functional T cell receptor mutants from a yeast surface-display library. Proc Natl Acad Sci U S A 96:5651-5656 (1999). PMID: 10318939.
  55. Crowley MP, Fahrer AM, Baumgarth N, Hampl J, Gutgemann I, Teyton L, Chien Y. A population of murine gammadelta T cells that recognize an inducible MHC class Ib molecule. Science 287:314-316 (2000). PMID: 10634788.
  56. Degano M, Garcia KC, Apostolopoulos V, Rudolph MG, Teyton L, Wilson IA. A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. Immunity 12:251-261 (2000). PMID: 10755612.
  57. Corper AL, Stratmann T, Apostolopoulos V, Scott CA, Garcia KC, Kang AS, Wilson IA, Teyton L. A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes. Science 288:505-511 (2000). PMID: 10775108.
  58. Benlagha K, Weiss A, Beavis A, Teyton L, Bendelac A. In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J Exp Med 191:1895-1903 (2000). PMID: 10839805.
  59. Stratmann T, Apostolopoulos V, Mallet-Designe V, Corper AL, Scott CA, Wilson IA, Kang AS, Teyton L. The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder. J Immunol 165:3214-3225 (2000). PMID: 10975837.
  60. Teyton L, Apostolopoulos V, Cantu C, 3rd, Celia H, Mallet-Designe V, Stefanko R, Stramann T, Wallace M. Function and dysfunction of T cell receptor: structural studies. Immunol Res 21:325-330 (2000). PMID: 10852133.
  61. Rudolph MG, Speir JA, Brunmark A, Mattsson N, Jackson MR, Peterson PA, Teyton L, Wilson IA. The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity. Immunity 14:231-242 (2001). PMID: 11290333.
  62. Wolan DW, Teyton L, Rudolph MG, Villmow B, Bauer S, Busch DH, Wilson IA. Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A. Nat Immunol 2:248-254 (2001). PMID: 11224525.
  63. Park SH, Weiss A, Benlagha K, Kyin T, Teyton L, Bendelac A. The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families. J Exp Med 193:893-904 (2001). PMID: 11304550.
  64. Rudolph MG, Huang M, Teyton L, Wilson IA. Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor. J Mol Biol 314:1-8 (2001). PMID: 11724527.
  65. Homann D, Teyton L, Oldstone MB. Differential regulation of antiviral T-cell Immunity results in stable CD8+ but declining CD4+ T-cell memory. Nat Med 7:913-919 (2001). PMID: 11479623.
  66. Chiu YH, Park SH, Benlagha K, Forestier C, Jayawardena-Wolf J, Savage PB, Teyton L, Bendelac A. Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat Immunol 3:55-60 (2002). PMID: 11731798.
  67. Lee PT, Benlagha K, Teyton L, Bendelac A. Distinct functional lineages of human V(alpha)24 natural killer T cells. J Exp Med 195:637-641 (2002). PMID: 11877486.
  68. Zhou XT, Forestier C, Goff RD, Li C, Teyton L, Bendelac A, Savage PB. Synthesis and NKT cell stimulating properties of fluorophore- and biotin-appended 6"-amino-6"-deoxy-galactosylceramides. Org Lett 4:1267-1270 (2002). PMID: 11950339.
  69. Benlagha K, Kyin T, Beavis A, Teyton L, Bendelac A. A thymic precursor to the NK T cell lineage. Science 296:553-555 (2002). PMID: 11968185.
  70. Bendelac A, Teyton L, Savage PB. Lipid presentation by CD1: the short and the long lipid story. Nat Immunol 3:421-422 (2002). PMID: 11976717.
  71. Luz JG, Huang M, Garcia KC, Rudolph MG, Apostolopoulos V, Teyton L, Wilson IA. Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions. J Exp Med 195:1175-1186 (2002). PMID: 11994422.
  72. Apostolopoulos V, Yu M, Corper AL, Teyton L, Pietersz GA, McKenzie IF, Wilson IA, Plebanski M. Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design. J Mol Biol 318:1293-1305 (2002). PMID: 12083518.
  73. Apostolopoulos V, Yu M, Corper AL, Li W, McKenzie IF, Teyton L, Wilson IA, Plebanski M. Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors. J Mol Biol 318:1307-1316 (2002). PMID: 12083519.
  74. Stetson DB, Mohrs M, Mallet-Designe V, Teyton L, Locksley RM. Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo. Immunity 17:191-200 (2002). PMID: 12196290.
  75. Tarbell KV, Lee M, Ranheim E, Chao CC, Sanna M, Kim SK, Dickie P, Teyton L, Davis M, McDevitt H. CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer. J Exp Med 196:481-492 (2002). PMID: 12186840.
  76. Procopio DO, Almeida IC, Torrecilhas AC, Cardoso JE, Teyton L, Travassos LR, Bendelac A, Gazzinelli RT. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d/NKT cell pathway. J Immunol 169:3926-3933 (2002). PMID: 12244192.
  77. Honey K, Benlagha K, Beers C, Forbush K, Teyton L, Kleijmeer MJ, Rudensky AY, Bendelac A. Thymocyte expression of cathepsin L is essential for NKT cell development. Nat Immunol 3:1069-1074 (2002). PMID: 12368909.
  78. Lee PT, Putnam A, Benlagha K, Teyton L, Gottlieb PA, Bendelac A. Testing the NKT cell hypothesis of human IDDM pathogenesis. J Clin Invest 110:793-800 (2002). PMID: 12235110.
  79. Zhu Y, Rudensky AY, Corper AL, Teyton L, Wilson IA. Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. J Mol Biol 326:1157-1174 (2003). PMID: 12589760.
  80. Mallet-Designe VI, Stratmann T, Homann D, Carbone F, Oldstone MB, Teyton L. Detection of low-avidity CD4+ T cells using recombinant artificial APC: following the antiovalbumin immune response. J Immunol 170:123-131 (2003). PMID: 12496391.
  81. Cantu C, 3rd, Benlagha K, Savage PB, Bendelac A, Teyton L. The paradox of immune molecular recognition of alpha-galactosylceramide: low affinity, low specificity for CD1d, high affinity for alpha beta TCRs. J Immunol 170:4673-4682 (2003). PMID: 12707346.
  82. Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest 112:902-914 (2003). PMID: 12975475.
  83. Zajonc DM, Elsliger MA, Teyton L, Wilson IA. Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A. Nat Immunol 4:808-815 (2003). PMID: 12833155.
  84. Forestier C, Park SH, Wei D, Benlagha K, Teyton L, Bendelac A. T cell development in mice expressing CD1d directed by a classical MHC class II promoter. J Immunol 171:4096-4104 (2003). PMID: 14530331.
  85. Zhou D, Cantu C, 3rd, Sagiv Y, Schrantz N, Kulkarni AB, Qi X, Mahuran DJ, Morales CR, Grabowski GA, Benlagha K, Savage P, Bendelac A, Teyton L. Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science 303:523-527 (2004). PMID: 14684827.
  86. Mitra AK, Celia H, Ren G, Luz JG, Wilson IA, Teyton L. Supine orientation of a murine MHC class I molecule on the membrane bilayer. Curr Biol 14:718-724 (2004). PMID: 15084288.
  87. Goff RD, Gao Y, Mattner J, Zhou D, Yin N, Cantu C, 3rd, Teyton L, Bendelac A, Savage PB. Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells. J Am Chem Soc 126:13602-13603 (2004). PMID: 15493902.
  88. Robey IF, Peterson M, Horwitz MS, Kono DH, Stratmann T, Theofilopoulos AN, Sarvetnick N, Teyton L, Feeney AJ. Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice. J Immunol 172:4624-4629 (2004). PMID: 15034081.
  89. Zhou D, Mattner J, Cantu C, 3rd, Schrantz N, Yin N, Gao Y, Sagiv Y, Hudspeth K, Wu YP, Yamashita T, Teneberg S, Wang D, Proia RL, Levery SB, Savage PB, Teyton L, Bendelac A. Lysosomal glycosphingolipid recognition by NKT cells. Science 306:1786-1789 (2004). PMID: 15539565.
  90. Malherbe L, Hausl C, Teyton L, McHeyzer-Williams MG. Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties. Immunity 21:669-679 (2004). PMID: 15539153.
  91. Kelker MS, Foss TR, Peti W, Teyton L, Kelly JW, Wuthrich K, Wilson IA. Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A. J Mol Biol 342:1237-1248 (2004). PMID: 15351648.
  92. Reiser JB, Teyton L, Wilson IA. Crystal structure of the Drosophila peptidoglycan recognition protein (PGRP)-SA at 1.56 A resolution. J Mol Biol 340:909-917 (2004). PMID: 15223330.
  93. Ranheim EA, Tarbell KV, Krogsgaard M, Mallet-Designe V, Teyton L, McDevitt HO, Weissman IL. Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene. AutoImmunity 37:555-567 (2004). PMID: 15763918.
  94. Brooks DG, Teyton L, Oldstone MB, McGavern DB. Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection. J Virol 79:10514-10527 (2005). PMID: 16051844.
  95. Wei DG, Lee H, Park SH, Beaudoin L, Teyton L, Lehuen A, Bendelac A. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med 202:239-248 (2005). PMID: 16027237.
  96. Zajonc DM, Cantu C, 3rd, Mattner J, Zhou D, Savage PB, Bendelac A, Wilson IA, Teyton L. Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nat Immunol 6:810-818 (2005). PMID: 16007091.
  97. Mattner J, Debord KL, Ismail N, Goff RD, Cantu C, 3rd, Zhou D, Saint-Mezard P, Wang V, Gao Y, Yin N, Hoebe K, Schneewind O, Walker D, Beutler B, Teyton L, Savage PB, Bendelac A. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 434:525-529 (2005). PMID: 15791258.
  98. Benlagha K, Wei DG, Veiga J, Teyton L, Bendelac A. Characterization of the early stages of thymic NKT cell development. J Exp Med 202:485-492 (2005). PMID: 16087715.
  99. Shore DA, Teyton L, Dwek RA, Rudd PM, Wilson IA. Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution. J Mol Biol 358:347-354 (2006). PMID: 16530222.
  100. Wei DG, Curran SA, Savage PB, Teyton L, Bendelac A. Mechanisms imposing the Vbeta bias of Valpha14 natural killer T cells and consequences for microbial glycolipid recognition. J Exp Med 203:1197-1207 (2006). PMID: 16651387.
  101. Liu Y, Goff RD, Zhou D, Mattner J, Sullivan BA, Khurana A, Cantu C, 3rd, Ravkov EV, Ibegbu CC, Altman JD, Teyton L, Bendelac A, Savage PB. A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells. J Immunol Methods 312:34-39 (2006). PMID: 16647712.
  102. Sagiv Y, Hudspeth K, Mattner J, Schrantz N, Stern RK, Zhou D, Savage PB, Teyton L, Bendelac A. Cutting edge: impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein. J Immunol 177:26-30 (2006). PMID: 16785493.
  103. Savage PB, Teyton L, Bendelac A. Glycolipids for natural killer T cells. Chem Soc Rev 35:771-779 (2006). PMID: 16936925.
  104. Brooks DG, Trifilo MJ, Edelmann KH, Teyton L, McGavern DB, Oldstone MB. Interleukin-10 determines viral clearance or persistence in vivo. Nat Med 12:1301-1309 (2006). PMID: 17041596.
  105. Bendelac A, Savage PB, Teyton L. The biology of NKT cells. Annu Rev Immunol 25:297-336 (2007). PMID: 17150027.
  106. Novak J, Beaudoin L, Park S, Griseri T, Teyton L, Bendelac A, Lehuen A. Prevention of type 1 diabetes by invariant NKT cells is independent of peripheral CD1d expression. J Immunol 178:1332-1340 (2007). PMID: 17237379.
  107. Schrantz N, Sagiv Y, Liu Y, Savage PB, Bendelac A, Teyton L. The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells. J Exp Med 204:841-852 (2007). PMID: 17389239.
  108. Sagiv Y, Bai L, Wei DG, Agami R, Savage PB, Teyton L, Bendelac A. A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d. J Exp Med 204:921-928 (2007). PMID: 17403933.
  109. Homann D, Lewicki H, Brooks D, Eberlein J, Mallet-Designe V, Teyton L, Oldstone MB. Mapping and restriction of a dominant viral CD4(+) T cell core epitope by both MHC class I and MHC class II. Virology 363:113-123 (2007). PMID: 17320138.
  110. Long X, Deng S, Mattner J, Zang Z, Zhou D, McNary N, Goff RD, Teyton L, Bendelac A, Savage PB. Synthesis and evaluation of stimulatory properties of Sphingomonadaceae glycolipids. Nat Chem Biol 3:559-564 (2007). PMID: 17660835.
  111. Scherer EM, Zwick MB, Teyton L, Burton DR. Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity. AIDS 21:2131-2139 (2007). PMID: 18090039.
  112. Teyton L. The saga of MHC-bound peptides: a renaissance for antigen presentation? J Clin Invest 117:3164-3166 (2007). PMID: 17975658.
  113. Liu Y, Deng S, Bai L, Freigang S, Mattner J, Teyton L, Bendelac A, Savage PB. Synthesis of diglycosylceramides and evaluation of their iNKT cell stimulatory properties. Bioorg Med Chem Lett 18:3052-3055 (2008). PMID: 18206371.
  114. Costantino V, Fattorusso E, Imperatore C, Mangoni A, Freigang S, Teyton L. Corrugoside, a new immunostimulatory alpha-galactoglycosphingolipid from the marine sponge Axinella corrugata. Bioorg Med Chem 16:2077-2085 (2008). PMID: 18037298.
  115. Zajonc DM, Savage P, Bendelac A, Wilson IA, Teyton L. Crystal structures of mouse CD1-i Gb3 complex and its cognate V[alpha]14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids. J Mol Biol 377:1104-1116 (2008). PMID: 18295796.
  116. Mattner J, Savage PB, Leung P, Oertelt SS, Wang V, Trivedi O, Scanlon ST, Pendem K, Teyton L, Hart J, Ridgway WM, Wicker LS, Gershwin ME, Bendelac A. Liver autoImmunity triggered by microbial activation of natural killer T cells. Cell Host Microbe 3:304-315 (2008). PMID: 18474357.
  117. Hovhannisyan Z, Angela Weiss A, Martin A, Wiesner M, Tollefsen S, Yoshida K, Ciszewski C, Curran SA, Murray JA, David CS, Sollid LM, Koning F, Teyton L, Jabri B. The role of HLA-DQ8 b57 polymorphism on the anti-gluten T cell response in celiac disease. Nature 456:534-538 (2008). PMID: 19037317.
  118. Levin D, DiPaolo RJ, Brinster C, Revilleza MJ, Boyd LF, Teyton L, Natarajan K, Mage MG, Shevach EM, Margulies DH. Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis. Eur J Immunol 38:3339-3353 (2008). PMID: 19039784.
  119. Shore DA, Issafras H, Landais E, Teyton L, Wilson IA. The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I. J Mol Biol 384:1190-1202 (2008). PMID: 18929574.
  120. Yin N, Long X, Goff R, Zhou D, Cantu Iii C, Mattner J, Saint-Mezard P, Teyton L, Bendelac A, Savage P. Alpha Anomers of iGb3 and Gb3 Stimulate Cytokine Production by Natural Killer T Cells. ACS Chem Biol 4:199-208 (2009). PMID: 19175331.
  121. Bai L, Sagiv Y, Liu Y, Freigang S, Yu KO, Teyton L, Porcelli SA, Savage PB, Bendelac A. Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer. Proc Natl Acad Sci U S A 106:10254-10259 (2009). PMID: 19506241.
  122. Landais E, Romagnoli PA, Corper AL, Shires J, Altman J, Wilson IA, Garcia KC, Teyton L. New design of MHC class II tetramers to accommodate fundamental principles of antigen presentation. J Immunol 183:7949-7957 (2009). PMID: 19923463.
  123. Yoshida K, Corper AL, Herro R, Jabri B, Wilson IA, Teyton L. The diabetogenic murine MHC class II molecule I-Ag7 is endowed with a switch which modulates TCR affinity.J Clin Invest: In Press. (2010).