Scripps Research Logo

The Asahara Laboratory - Publications

Selected Publications:

  1. Y. Kawakami, M. Tsuda, S. Takahashi, N. Taniguchi, C.R. Esteban, M. Zemmyo, T. Furumatsu, M. Lotz, J.C. Belmonte, H. Asahara, "Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9". Proc Natl Acad Sci U S A, 102(7): 2414-9, 2005.
  2. T. Furumatsu, M. Tsuda, K. Yoshida, N. Taniguchi, T. Ito, M. Hashimoto, H. Asahara, "Sox9 and p300 cooperatively regulate chromatin-mediated transcription". J Biol Chem, 2005 in press.
  3. T. Furumatsu, M. Tsuda, N. Taniguchi, Y. Tajima, H. Asahara, "Smad3 induces chondrogenesis through the activation of SOX9 via CBP/p300 recruitment". J Biol Chem, 280(9): 8343-50, 2005.
  4. T. Kato, H. Asahara, M.S. Kurokawa, K. Fujisawa, T. Hasunuma, H. Inoue, M. Tsuda, S. Takahashi, S. Motokawa, T. Sumida, K. Nishioka, "HTLV-I env protein acts as a major antigen in patients with HTLV-I-associated arthropathy". Clin Rheumatol, 23(5): 400-9, 2004.
  5. K. Nishida, T. Komiyama, S. Miyazawa, Z.N. Shen, T. Furumatsu, H. Doi, A. Yoshida, J. Yamana, M. Yamamura, Y. Ninomiya, H. Inoue, H. Asahara, "Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression". Arthritis Rheum, 50(10): 3365-76, 2004.
  6. S. Omoto, K. Nishida, Y. Yamaai, M. Shibahara, T. Nishida, T. Doi, H. Asahara, T. Nakanishi, H. Inoue, M. Takigawa, "Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage". Osteoarthritis Cartilage, 12(10): 771-8, 2004.
  7. G. Canettieri, I. Morantte, E. Guzman, H. Asahara, S. Herzig, S.D. Anderson, J.R. Yates, M. Montminy, "Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex". Nat Struct Biol, 10(3): 175-81, 2003.
  8. Y. Kawakami, J. Rodriguez-Leon, C.M. Koth, D. Buscher, T. Itoh, A. Raya, J.K. Ng, C.R. Esteban, S. Takahashi, D. Henrique, M.F. Schwarz, H. Asahara, J.C. Izpisua Belmonte, "MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb". Nat Cell Biol, 5(6): 513-9, 2003.
  9. M. Tsuda, S. Takahashi, Y. Takahashi, H. Asahara, "Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9". J Biol Chem, 278(29): 27224-9, 2003.
  10. H. Asahara, S. Tartare-Deckert, T. Nakagawa, T. Ikehara, F. Hirose, T. Hunter, T. Ito, M. Montminy, "Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro". Mol Cell Biol, 22(9): 2974-83, 2002.
  11. H. Asahara, B. Santoso, E. Guzman, K. Du, P.A. Cole, I. Davidson, M. Montminy, "Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB". Mol Cell Biol, 21(23): 7892-900, 2001.
  12. F. Long, E. Schipani, H. Asahara, H. Kronenberg, M. Montminy, "The CREB family of activators is required for endochondral bone development". Development, 128(4): 541-50, 2001.
  13. W. Xu, H. Chen, K. Du, H. Asahara, M. Tini, B.M. Emerson, M. Montminy, R.M. Evans, "A transcriptional switch mediated by cofactor methylation".Science, 294(5551): 2507-11, 2001.
  14. K. Asaumi, T. Nakanishi, H. Asahara, H. Inoue, M. Takigawa, "Expression of neurotrophins and their receptors (TRK) during fracture healing". Bone, 26(6): 625-33, 2000.
  15. K. Du, H. Asahara, U.S. Jhala, B.L. Wagner, M. Montminy, "Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo". Mol Cell Biol, 20(12): 4320-7, 2000.
  16. L.F. Michael, H. Asahara, A.I. Shulman, W.L. Kraus, M. Montminy, "The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism". Mol Cell Biol, 20(5): 1596-603, 2000.
  17. H. Asahara, S. Dutta, H.Y. Kao, R.M. Evans, M. Montminy, "Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner". Mol Cell Biol, 19(12): 8219-25, 1999.