Integrative Structural and Computational Biology

Structural and computational biology are continuously evolving with significant advances, particularly in cryo-electron microscopy (cryo-EM), X-ray crystallography and nuclear magnetic resonance (NMR) technology. Such advances in technologies, methodologies, and accelerated throughput are enabling rapid determination of structures of important biological molecules and complex assemblies of molecules. Molecular structures that only a few years ago seemed impossible to decipher are now being solved with remarkable regularity.

In addition, powerful computation and bioinformatics are playing an increasingly important role in all facets of biological research. The integration of computational methods with the current arsenal of biophysical techniques is critical for understanding complex biological systems. This is already paying huge dividends where seemingly intractable problems can be approached using a combination of methods.