Nuclear Magnetic Resonance

The Nuclear Magnetic Resonance Facility provides state-of-the-art NMR spectroscopy and molecular modeling services to the research staff and students of Scripps Research's Department of Chemistry.

The facility houses a total of six spectrometers including a Bruker DRX-600 equipped with a 5mm DCH cryoprobe, Bruker DRX-500, Varian Inova-400, Bruker AMX-400, Varian Mercury-300 and Bruker AC-250. All instruments (except the AC-250) are fully equipped for multi-nuclear 1D and 2D NMR experiments. The DRX-600 is also equipped with triple-axis gradient accessories for advanced NMR experiments. The Inova-400 is equipped with an MAS Nanoprobe for NMR experiments of compounds on solid support, and for small quantity samples. Additional supporting instrumentation includes a Bruker Vector-33 FT-IR, workstations for offline data processing, the spectral prediction software from ACD, and Schrodinger molecular modeling software.


The core has four Bruker nuclear magnetic resonance (NMR) instruments:

  • Bruker AVANCE III 700 MHz instruments with QCI Cryoprobe.
  • Bruker AVANCE NEO 600 MHz instruments with TCI Cryoprobe and SampleCase
  • Bruker AVANCE NEO 400 MHz instruments with SampleXpress
  • Bruker AVANCE 400 MHz instruments with SampleXpress
Those instruments perform all sorts of multi-dimension NMR experiments, and detect a variety of nuclei. By connecting these highly sensitive instruments to the internet via a proprietary Scripps Florida server, our scientists and their collaborators can access the collected data from their office or laboratory.

Training, various experiments setup, data collection and analysis:

While priority of use is always given to Scripps Research Florida researchers, time on the instruments is also made available on a fee-for-service basis to outside users.

Fee-for-Service Pricing
(Subject to change; call for current pricing and quotes)

All spectra are run by Scripps Florida personnel, and results are accessible to outside customers by a proprietary Internet link.

  •     Time on 400 MHz instrument: $80/hour
  •     Time on 700 MHz instrument: Call for pricing