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Lars Hangartner, Ph.D.

Associate Professor of Ims
Department of Immunology and Microbiology
California Campus
Scripps VIVO Scientific Profile
lhangart@scripps.edu
(858) 784-9876

Education

Ph.D., Eidgenössische Technische Hochschule 2002
Diploma (Molecular Biology), University of Zurich 1997

Professional Experience

2015-2017 Associate Professor, Immunology and Microbial Science (IMS), The Scripps Research Institute
2009-2015 Professor SNSF, Institute of Medical Virology, University of Zurich
2008-2009 Staff Scientist, University of Zurich
2005-2008 Senior Research Associate, The Scripps Research Institute
2002-2005 Postdoctoral Fellow, University Hospital Zurich

Selected References

All Publications

Burton, D. R. & Hangartner, L. Broadly neutralizing antibodies to HIV and their role in vaccine design. (2016). Annual Review of Immunology, 34, 635.

Wyrzucki, A., Bianchi, M., Kohler, I., Steck, M. & Hangartner, L. Heterosubtypic antibodies to influenza A virus have limited activity against cell-bound virus but are not impaired by strain-specific serum antibodies. (2015). Journal of Virology, 89(6), 3136-3144. PMCID: PMC4337524.

Kohler, I., Kouyos, R., Bianchi, M., Grube, C., Wyrzucki, A., Gunthard, H. F. & Hangartner, L. The impact of vaccination on the breadth and magnitude of the antibody response to influenza A viruses in HIV-infected individuals. (2015). AIDS, 29(14), 1803-1810.

Wyrzucki, A., Dreyfus, C., Kohler, I., Steck, M., Wilson, I. A. & Hangartner, L. Alternative recognition of the conserved stem epitope in influenza A virus hemagglutinin by a VH3-30-encoded heterosubtypic antibody. (2014). Journal of Virology, 88(12), 7083-7092. PMCID: PMC4054347.

Kohler, I., Scherrer, A. U., Zagordi, O., Bianchi, M., Wyrzucki, A., Steck, M., Ledergerber, B., Gunthard, H. F. & Hangartner, L. Prevalence and predictors for homo- and heterosubtypic antibodies against influenza A virus.. (2014). Clinical Infectious Diseases, 59(10), 1386-1393.

Hoot, S., McGuire, A. T., Cohen, K. W., Strong, R. K., Hangartner, L., Klein, F., Diskin, R., Scheid, J. F., Sather, D. N., Burton, D. R. & Stamatatos, L. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs.. (2013). PLoS Pathogens, 9, e1003106. PMCID: PMC3536657.

Ota, T., Doyle-Cooper, C., Cooper, A. B., Huber, M., Falkowska, E., Doores, K. J., Hangartner, L., Le, K., Sok, D., Jardine, J., Lifson, J., Wu, X. L., et al. Anti-HIV B Cell lines as candidate vaccine biosensors. (2012). Journal of Immunology, 189(10), 4816-4824. PMCID: PMC3626558.

Hessell, A. J., Rakasz, E. G., Poignard, P., Hangartner, L., Landucci, G., Forthal, D. N., Koff, W. C., Watkins, D. I. & Burton, D. R. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. (2009). PLoS Pathogens, 5, e1000433. PMCID: PMC2674935.

Hessell, A. J., Poignard, P., Hunter, M., Tehrani, D. M., Bleeker, W. K., Parren, Pwhi, Marx, P. A., Burton, D. R. & Hangartner, L. Effective, low-titer antibody protection against low-dose repeated mucosal shiv challenge in macaques. (2009). Nature Medicine, 15(8), 951-954. PMCID: PMC4334439.

Geuking, M. B., Weber, J., Dewannieux, M., Gorelik, E., Heidmann, T., Hengartner, H., Zinkernagel, R. M. & Hangartner, L. Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration. (2009). Science, 323(5912), 393-396.