Holiday Greetings from TSRI's President

Happy Holidays!

While the holidays are typically a busy time of year for gatherings of friends and family, the season also provides us with the opportunity for reflection on recent accomplishments as well as a commitment to new goals and initiatives for the coming year. I can say without hesitation that 2002 was another extraordinary year in the history of the Institute, and it is the collective effort of our entire community that has enabled us to reach this stage in our development and facilitate the prodigious contributions of our scientists. TSRI is not only viewed by our peers as an exceptional environment in which to conduct the scientific enterprise, but the collegiality and conviviality within the halls of the institution is palpable and exciting.

We were pleased to welcome Kurt Wüthrich as a visiting professor to TSRI and The Skaggs Institute this year, and congratulate him on receiving the 2002 Nobel Prize in Chemistry for his work in applying nuclear magnetic resonance to solving the structures of biological macromolecules. In an institution with exceptional strength and depth in structural biology, Kurt's presence creates unprecedented opportunities for increased collaborations and innovation. We look forward to his spending more and more time here as he transitions to a full-time commitment to TSRI in the near future.

TSRI's Graduate Program continues to be ranked among the top graduate programs in the country, according to a survey conducted by U.S. News & World Report. That a program launched only 13 years ago can successfully compete with the most established, elite graduate schools in the country is testimony to its vision, as well as the tenacity and leadership of its founding and current deans. Further, we are proud that this year the Graduate Program became known as the Kellogg School of Science and Technology, to honor the extraordinary contributions to science and education of philanthropists Jean and Keith Kellogg.

This year also marked the launch of TSRI's newest scientific initiative, the Center for Integrative Molecular Biosciences (CIMBio), an interdisciplinary facility organized to combine the use of x-ray crystallography and electron microscopy to unravel the structure and function of molecular assemblies of the cell. Directed by Professor Ron Milligan, the program's centerpiece is a suite containing six state-of-the-art electron microscopy rooms, making CIMBio one of the most advanced facilities of its kind in the world.

In addition, a group of TSRI scientists, led by Martin Friedlander and Paul Schimmel, received a five-year, $9.6 million grant from the National Eye Institute to study the leading causes of blindness and to develop treatments for patients with neovascular eye disease. Their work focuses on a new class of anti-angiogenic molecules that may prove useful in the treatment of these devastating eye disorders.

Numerous members of the faculty were recognized by their peers this year for their scientific achievements. Francis Chisari and Chi-Huey Wong were elected to membership in the National Academies of Science, K.C. Nicolaou received the Tetrahedron Award, Albert Eschenmoser received the Oparin Medal and Julius Rebek was honored with the Chemical Pioneer Award. Ian Wilson was elected to the American Academy of Arts and Sciences, and Ben Cravatt was named one of the country's 100 young innovators by MIT's magazine, Technology Review. On an institutional level, TSRI was ranked second in the world among high-impact institutions in chemistry.

My sincerest thanks to the members of TSRI's faculty, as well as the myriad technical and administrative support staff who work hand-in-hand with them, for a truly memorable year. I am proud to be associated with so many talented and dedicated individuals, and grateful for their exceptional achievements on behalf of the organization. My best wishes for a happy, healthy and prosperous new year.


Richard A. Lerner














"TSRI is not only viewed by our peers as an exceptional environment in which to conduct the scientific enterprise, but the collegiality and conviviality within the halls of the institution is palpable and exciting."

—Richard A. Lerner