One of the world’s largest collections of medicines is being mined for new treatments

December 20, 2018


This video by Boston Globe’s STAT magazine features Calibr’s ReFRAME collection, a drug repurposing project that’s finding ways to treat new diseases with existing drugs. The Calibr scientists are using this collection, called ReFRAME, to identify existing drugs that show promise for treating major diseases. As a result of this ReFRAME initiative, two FDA-approved drugs are already being tested in clinical trials—one as a treatment for tuberculosis and another for the parasite Cryptosporidium spp., a major cause of severe diarrhea—within only a few short years of Calibr scientists discovering their utility. This is in contrast to the much longer timelines that often hinder new drug development.


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