Scripps Research Logo

The Koziol Laboratory

Publications

Papers
2000 - 2004
1995 - 1999
1990 - 1994
1985 - 1989
1980 - 1984
1975 - 1979

Books

2000 - 2004

Kunicki TJ, Federici AB, Salomon DR, Koziol JA, Head SR, Mondala TS, Chismar JD, Baronciani L, Canciani MT, Peake IR. An association of candidate gene haplotypes and bleeding severity in Von Willebrand Disease (VWD) type 1 pedigrees. Blood. 2004 Jun 29. Abstract

Koziol JA, Feng AC. A note on the genome scan meta-analysis statistic. Ann Hum Genet. 2004 Jul;68(Pt 4):376-80. Abstract

Fuller DB, Koziol JA, Feng AC. Prostate brachytherapy seed migration and dosimetry: analysis of stranded sources and other potential predictive factors. Brachytherapy. 2004;3(1):10-9. Abstract

Fukuda S, Fini CA, Mabuchi T, Koziol JA, Eggleston LL Jr, del Zoppo GJ. Focal cerebral ischemia induces active proteases that degrade microvascular matrix. Stroke. 2004 Apr ;35(4):998-1004. Epub 2004 Mar 04. Abstract

Nagel S, Wagner S, Koziol J, Kluge B, Heiland S. Volumetric evaluation of the ischemic lesion size with serial MRI in a transient MCAO model of the rat: comparison of DWI and T1WI. Brain Res Brain Res Protoc. 2004 Feb;12(3):172-9. Abstract

Wagner S, Kluge B, Koziol JA, Grau AJ, Grond-Ginsbach C. MMP-9 polymorphisms are not associated with spontaneous cervical artery dissection. Stroke. 2004 Mar;35(3):e62-4. Epub 2004 Feb 12. Abstract

Fritzler MJ, Wiik A, Tan EM, Smolen JS, McDougal JS, Chan EK, Gordon TP, Hardin JA, Kalden JR, Lahita RG, Maini RN, Reeves WH, Rothfield NF, Takasaki Y, Wilson M, Byrd MG, Slivka L, Koziol JA. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories. J Rheumatol. 2003 Nov ;30(11):2374-81. Abstract

Koziol JA, Zhang JY, Casiano CA, Peng XX, Shi FD, Feng AC, Chan EK, Tan EM. Recursive partitioning as an approach to selection of immune markers for tumor diagnosis. Clin Cancer Res. 2003 Nov 1;9(14):5120-6. Abstract

Wagner S, Nagel S, Kluge B, Schwab S, Heiland S, Koziol J, Gardner H, Hacke W. Topographically graded postischemic presence of metalloproteinases is inhibited by hypothermia. Brain Res. 2003 Sep 12 ;984(1-2):63-75. Abstract

Ohyama H, Hosomi N, Takahashi T, Mizushige K, Osaka K, Kohno M, Koziol JA. Comparison of Magnetic Resonance Imaging and Transesophageal Echocardiography in Detection of Thrombus in the Left Atrial Appendage. Stroke. 2003 Sep 11. Abstract

Horstmann S, Kalb P, Koziol J, Gardner H, Wagner S. Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: influence of different therapies. Stroke. 2003 Sep;34(9):2165-70. Epub 2003 Aug 07. Abstract

Goodman G.R., Burian C., Koziol J.A., Saven A. Extended follow-up of patients with hairy cell leukemia after treatment with cladribine. J. Clin. Oncol. 2003;21:891-896. Abstract

Zhang J.Y., Casiano C.A., Peng X.X., Koziol J.A., Chan E.K., Tan E.M. Enhancement of antibody detection in cancer using panel of recombinant tumor-associated antigens. Cancer Epidem. Biomarkers Prev. 2003;12:136-143. Abstract

Eddleston J., Christiansen S.C., Jenkins G.R., Koziol J.A., Zuraw B.L. Bradykinin increases the in vivo expression of the CXC chemokine receptors CXCR1 and CXCR2 in patients with allergic rhinitis. J. Aller. Clin. Immunol. 2003 ;111:106-112. Abstract

Tan E.M., Smolen J.S., McDougal J.S., Fritzler M.J., Gordon T., Hardin J.A., Kalden J.R., Lahita R.G., Maini R.N., Reeves W.H., Rothfield N.F., Takasaki Y., Wiik A., Wilson M., Koziol J.A. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content. J Rheumatol. 29:68-74, 2002. Abstract

Parsons C.L., Dell J., Stanford E.J., Bullen M., Kahn B.S., Waxell T., Koziol J.A. Increased prevalence of interstitial cystitis: previously unrecognized urologic and gynecologic cases identified using a new symptom questionnaire and intravesical potassium sensitivity. Urology 2002;60:573-578. Abstract

Mathison D.A., Koziol J.A. Marginal utility of montelukast for persistent asthma. Chest 121:334-337, 2002. Abstract

Koziol J.A., Zuraw B.L., Christiansen S.C. Health care consumption among elderly patients in California: a comprehensive 10-year evaluation of trends in hospitalization rates and charges. Gerontologist 42:207-216, 2002. Abstract

Koziol J.A., Felitti V.J., Beutler E. The effect of HFE genotypes on measurements of iron overload. (letter). Ann. Intern. Med. 2002;137:700-701. Abstract

Beutler E., Felitti V.J., Koziol J.A., Ho N.J., Gelbart T. Penetrance of 845G--> A (C282Y) HFE hereditary haemochromatosis mutation in the USA. (letter). Lancet 359:211-218, 2002. Abstract

Koziol J.A., Ho N.J., Felitti V.J., Beutler E. Reference centiles for serum ferritin and percentage of transferrin saturation, with application to mutations of the HFE gene. Clin. Chem. 47:1804-1810, 2001. Abstract

Hosomi N., Mizushige K., Ohyama H., Takahashi T., Kitadai M., Hatanaka Y., Matsuo H., Kohno M., Koziol J.A.. Angiotensin-converting enzyme inhibition with enalapril slows progressive intima-media thickening of the common carotid artery in patients with non-insulin-dependent diabetes mellitus. Stroke 32:1539-1545, 2001. Abstract

Hosomi N., Lucero J., Heo J.H., Koziol J.A., Copeland B.R., del Zoppo G.J. Rapid differential endogenous plasminogen activator expression after acute middle cerebral artery occlusion. Stroke 32:1341-1348, 2001. Abstract

Wagner S., Schnippering H., Aschoff A., Koziol J.A., Schwab S., Steiner T. Suboptimum hemicraniectomy as a cause of additional cerebral lesions in patients with malignant infarction of the middle cerebral artery. J. Neurosurg. 94:693-696, 2001. Abstract

Jacquelin B., Rozenshteyn D., Kanaji S., Koziol J.A., Nurden A.T., Kunicki T.J. Characterization of inherited differences in transcription of the human integrin alpha 2 gene. J. Biol. Chem. 276:23518-24, 2001. Abstract

Jacquelin B., Tarantino M.D., Kritzik M., Rozenshteyn D., Koziol J.A., Nurden A.T., Kunicki T.J. Allele-dependent transcriptional regulation of the human integrin alpha(2) gene. Blood 97:1721-1726, 2001. Abstract

Koziol J.A., Wagner S., Sobel D.F., Slivka L.S., Romine J.S., Sipe J.C., Adams H.P. Predictive value of lesions for relapses in relapsing-remitting multiple sclerosis. Am. J. Neuroradiol. 22:284-291, 2001. Abstract

Adams H.-P., Koziol J.A. Progressive cerebral atrophy in MS: a serial study using registered, volumetric MRI. (letter). Neurology 55:1242-1243, 2000. Abstract

Wagner S., Adams H.-P., Sobel D.F., Slivka L.S., Sipe J.C., Romine J.S., Koziol J.A. New hypointense lesions on MRI in relapsing-remitting multiple sclerosis patients. Eur. Neurol. 43:194-200, 2000. Abstract

Shadan F.F., Koziol J. Induced genomic instability as a potential screening test for cancer susceptibility? Med Hypotheses 55:69-72, 2000. Abstract

Mathison D.A., Koziol J.A. Persistent asthma: patient characteristics, courses of asthma, and utility of salmeterol. J. Asthma 37:441-450, 2000. Abstract

Schleicher N.C., Koziol J.A., Christansen S.C. Asthma mortality rates among California youths. J. Asthma 37:259-265, 2000. Abstract

Beutler E., Koziol J.A. The cladribine trial in multiple sclerosis: a reanalysis. Neuroepidemiology 19:109-112, 2000. Abstract

Abumiya T., Fitridge R., Mazur C. et al. Integrin alpha(IIb)beta(3) inhibitor preserves microvascular patency in experimental acute focal cerebral ischemia. Stroke 31:1402-1410,2000. Abstract

1995 - 1999

Koziol J.A., Tuckwell H.C. A Bayesian method for combining independent tests. Journal of Statistical Planning and Inference 78:317-323, 1999. Abstract

Koziol J.A., Beutler B. Estimation of physical distance in the genome through probabilistic analysis of marker density and yeast artificial chromosome (YAC) size. Biom. J. 41:251-257, 1999. Abstract

Koziol J.A., Lucero A., Sipe J.C., Romine J.S., Beutler E. Responsiveness of the Scripps neurologic rating scale during a multiple sclerosis clinical trial. Can. J. Neurol. Sci. 26:283-289, 1999. Abstract

Adams H.P., Wagner S., Sobel D.F., Slivka L.S., Sipe J.C., Romine J.S., Beutler E., Koziol J.A. Hypointense and hyperintense lesions on magnetic resonance imaging in secondary-progressive MS patients. European Neurology 42:52-63, 1999. Abstract

Abumiya T., Lucero J., Heo J.H., Tagaya M., Koziol J.A., Copeland B.R., del Zoppo G.J. Activated microvessels express vascular endothelial growth factor and integrin alpha(v)beta3 during focal cerebral ischemia. J. Cereb. Blood Flow Metab. 19:1038-1050, 1999. Abstract

Heo J.H., Lucero J., Abumiya T., Koziol J.A., Copeland B.R., del Zoppo G.J. Matrix metallo- proteinases increase very early during experimental focal cerebral ischemia. J. Cereb. Blood Flow Metab. 19:624-633, 1999. Abstract

Tan E.M., Smolen J.S., McDougal J.S., Koziol J.A. A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities. I. Precision, sensitivity, and specificity. Arthritis Rheum. 42:455-464, 1999. Abstract

Saven A., Burian C., Adusumalli J., Koziol J.A. Filgrastim for cladribine-induced neutropenic fever in patients with hairy cell leukemia. Blood 93:2471-2477, 1999. Abstract

Giese N.A., Marijianowski M.M.H., McCook O. et al. The role of alpha and beta platelet-derived growth factor receptor in the vascular response to injury of nonhuman primates. Arteriosclerosis, Thrombosis and Vascular Biology 19:900-909, 1999. Abstract

Ho N.J., Koziol J.A., Parsons C.L., Barlow W., Weiss N.S. Natural history of interstitial cystitis in 274 patients receiving sulfated polysaccharide therapy. Urology 53:1133-1139, 1999. Abstract

Ho N., Koziol J.A., Parsons C.L. Interstitial cystitis. In P. Manu, ed. Functional Somatic Syndromes. Cambridge University Press, Cambridge, 1998, pp. 98-126. ISBN: 0521591309

Saven A., Burian C., Koziol J.A., Piro L.D. Long term follow-up of patients with hairy cell leukemia after cladribine treatment. Blood 92:1918-1926, 1998. Abstract

Koziol J.A., Wagner S., Adams H.-P. Assessing information in T2-weighted MRI scans from secondary progressive MS patients. Neurology 51:228-233, 1998. Abstract

Koziol, J.A. A non-parametric index of tracking. J. Appl. Statist. 25:181-191, 1998. Abstract

Ho, N., Koziol, J.A. and Parsons, C.L. Epidemiology of interstitial cystitis. In G.R. Sant, ed. Interstitial Cystitis. Lippencott-Raven, Philadelphia, 1997, pp. 9-16. ISBN: 0-397-51695-9

Koziol, J.A., Alexander, J.E., Bauer, L.O. et al. A graphical technique for displaying correlation matrices. American Statistician 51:301-304, 1997. Abstract

Wagner, S., Tagaya, M., Koziol, J.A., Quaranta, V. and Del Zoppo, G.J. Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion. Stroke 28:858-865, 1997. Abstract

Tan, E.M., Feltkamp, T.E., ..., and Koziol, J.A. Range of antinuclear antibodies in "normal" individuals. Arthritis Rheum. 40:1601-1611, 1997. Abstract

Christiansen , S.C. , Martin, S.B., Schleicher , N.C. , Koziol, J.A., Mathews, K.P., and Zuraw, B.L. Evaluation of a school-based asthma education program for inner-city children. J. Allergy Clin. Immunol. 100:613-617, 1997. Abstract

Beutler, E., Carson, D., Sipe, J.C. et al. 2-Chlorodeoxyadenosine in nonmalignant disorders. In B.D. Cheson, M.J. Keating, and W. Plunkett, eds. Nucleoside Analogs in Cancer Therapy. Marcel Dekker, New York, 1997, pp. 359-382. ISBN: 0-8247-9850-3

Romine, J.S., Sipe, J.C., Koziol, J.A. et al. Cladribine: Use in therapy of multiple sclerosis. BioDrugs 7:386-393, 1997.

Koziol, J.A. and Wu, S.-C.H. A review of nonparametric tests for changepoint problems, with application to a recombinant drug therapy clinical trial. J. Biopharm. Statist. 6:425-441, 1996. Abstract

Koziol, J.A. and Wu, S.-C.H. Changepoint statistics for assessing a treatment-covariate interaction. Biometrics 52:1147-1152, 1996. Abstract

Koziol, J.A. A note on Lancaster 's procedure for the combination of independent events. Biom. J. 38:653-660, 1996.

Koziol, J.A. A weighted Kuiper statistic for goodness of fit. Statist. Neer. 50:394-403, 1996.

Koziol, J.A. A note on signed rank tests for the changepoint problem. Statistics 27:325-338, 1996.

Koziol, J.A. Comment on the statistical power of EDF tests of normality and the sample size required to distinguish geometric-normal (lognormal) from arithmetic-normal distributions of low variability. J. Theor. Biol. 180:81-85, 1996. PDF

Okada, Y., Copeland, B.R., Hamann, G.F., Koziol, J.A., Cheresh, D.R., and Del Zoppo, G.J. Integrin a2b3 is expressed in selected microvessels after focal cerebral ischemia. Amer. J. Pathol. 149:37-44, 1996. Abstract

Haring, H.-P., Akamine, P., Haberman, R., Koziol, J.A., and Del Zoppo, G.J. Distribution of integrin-like immunoreactivity in primate brain microvasculature. J. Neurol. Exp. Neuropathol. 55:236-245, 1996. Abstract

Tuckwell, H.C. and Koziol, J.A. On the concentration of 5-hydroxyindoleacetic acid in shizophrenia: A meta-analysis. Psych. Res. 59:239-244, 1996. Abstract

Christiansen , S.C. , Martin, S.B., Schleicher , N.C. , Koziol, J.A., Hamilton , R.G. and Zuraw, B.L. Exposure and sensitization to environmental allergen of predominantly Hispanic children with asthma in San Diego's inner city. J. Allergy Clin. Immunol. 98:288-294, 1996. Abstract

Christiansen, S.C., Martin, S.B., Schleicher, N.C., Koziol, J.A., Matthews, K.P. and Zuraw, B.L. Current prevalence of asthma-related symptoms in San Diego's predominantly Hispanic inner-city children. J. Asthma 33:17-26, 1996. Abstract

Schmid, E., Koziol, J.A., and Babior, B.M. Enhancement of protein kinase C-dependent O2 production in Epstein-Barr virus-transformed B lymphocytes by p120 Ras-GAP antisense oligonucleotide. J. Biol. Chem. 271:9320-9325, 1996. Abstract

Sobol, R.E., Fakhrai, H., Shawler, D. et al. Immuno-gene therapy of colon carcinoma and central nervous system tumors. In M.K. Brenner and R.C. Moen, eds. Gene Therapy in Cancer. Marcel Dekker, New York, 1996, pp.205-214. ISBN:  0824794818

Sipe, J.C., Romine, J.S., Zyroff, J., Koziol, J. and Beutler, E. Treatment of multiple sclerosis with cladribine. In D.E. Goodkin and R.A. Rudick, eds. Mutliple Sclerosis: Advances in Clinical Trial Design, Treatment and Future Perspectives. Springer-Verlag, London, 1996, pp.313-334. ISBN: 1852330333

Sipe, J.C., Romine, J.S., Koziol, J.A., McMillan, R., Zyroff, J. and Beutler, E. Development of cladribine treatment in multiple sclerosis. Multiple Sclerosis 1:343-347, 1996. Abstract

Beutler, E., Sipe, J., Romine, J. et al. Treatment of multiple sclerosis and other autoimmune diseases with cladribine. Sem. Hematol. 33 Suppl. 1:45-52, 1996. Abstract

Beutler, E., Sipe, J.C., Romine, J.S., Koziol, J.A., McMillan, R. and Zyroff, J. The treatment of chronic progressive multiple sclerosis with cladribine. Proc. Natl. Acad. Sci. USA 93:1716-1720, 1996. Abstract

Koziol, J.A., Frutos, A., Sipe, J.C., Romine, J.S. and Beutler, E. A comparison of two neurologic scoring instruments for multiple sclerosis. J. Neurol. 243:209-213, 1996. Lengthier version in 1996 ASA Proc. Biopharm., pp. 50-55. Abstract

Koziol, J.A., Adams, H.-P., and Frutos, A. Discrimination between the ulcerous and the nonulcerous forms of interstitial cystitis by noninvasive findings. J. Urol. 155:87-90, 1996. Abstract

Koziol, J.A., Lee, P.P., Dillman, R.O., Fagnani, R. and Halpern, S. Pharmacokinetics of 111In-labelled monoclonal antibody ZCE-025 and fragments in tumour-bearing mice. Nuclear Medicine Communications 16:299-305, 1995. Abstract

Adams , H.-P. and Koziol, J.A. Prediction of binding to MHC class I molecules. J. Immunol. Meth. 185:181-190, 1995. Abstract

Fakhrai, H., Shawler, D.L., Gjerset, R. et al. Cytokine gene therapy with interleukin-2-transduced fibroblasts: effects of IL-2 dose on anti-tumor immunity. Human Gene Therapy 6:591-601, 1995. Abstract

Sobol, R.E., Royston, I., Fakhrai, H. et al. Injection of colon carcinoma patients with autologous irradiated tumor cells and fibroblasts genetically modified to secrete interleukin-2: a phase I study. Human Gene Therapy 6:195-204, 1995. Abstract

Sobol, R.E., Fakhrai, H., Shawler, D. et al. Interleukin-2 gene therapy in a patient with glioblastoma. Gene Therapy 2:164-167, 1995. Abstract

Saven, A., Emanuele, S., Kosty, M., Koziol, J., Ellison, D. and Piro, L. 2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma. Blood 86:1710-1716, 1995. Abstract

Darko, D.F., Miller, J.C., Gallen, C. et al. Sleep electroencephalogram delta-frequency amplitude, night plasma levels of tumor necrosis factor a, and human immunodeficiency virus infection. Proc. Natl. Acad. Sci. USA 92:12080-12084, 1995. Abstract

1990 - 1994

Koziol, J.A. and Tuckwell, H.C. A weighted nonparametric procedure for the combination of independent events. Biom. J. 36:1005-1012, 1994.

Tsai, K.T. and Koziol, J.A. Assessing multiple endpoints with ordered alternatives. Commun. Statist. Theor. Meth. 23:533-544, 1994.

Rudolph, R., Tripuraneni, P., Koziol, J.A., McKean-Matthews, M. and Frutos, A. Normal transcutaneous oxygen pressure in skin after radiation therapy for cancer. Cancer 74: 3063-3070, 1994. Abstract

Zuraw, B.L., Sugimoto, S., Parsons, C.L., Hugli, T., Lotz, M. and Koziol, J. Activation of urinary kallikrein in patients with interstitial cystitis. J. Urol. 152:874-878, 1994. Abstract

Lotz, M., Villiger, P., Hugli, T., Koziol, J. and Zuraw, B.L. Interleukin-6 and interstitial cystitis. J. Urol. 152: 869-873, 1994. Abstract

Okada, Y., Copeland, B.R., Fitridge, R., Koziol, J.A., and Del Zoppo, G.J. Fibrin contributes to microvascular obstructions and parenchymal changes during early focal cerebral ischemia and reperfusion. Stroke 25:1847-1854, 1994. Abstract

Sipe, J., Koziol, J., Romine, J., and Beutler, E. Cladribine treatment of multiple sclerosis (letter). Lancet 344: 537-538, 1994.

Sipe, J.D., Romine, J.S., Koziol, J.A., Mcmillan, R., Zyroff, J., and Beutler, E. Cladribine in treatment of chronic progressive multiple sclerosis. Lancet 344:9-13, 1994. Abstract

Beutler, E., Koziol, J.A., Mcmillan, R., Sipe, J.C., Romine, J.S., and Carrera, C.J. Marrow suppression produced by repeated doses of cladribine. Acta Haematol. 91:10-15, 1994. Abstract

Koziol, J.A. Epidemiology of interstitial cystitis. Urologic Clinics of North America 21:7-20, 1994. Abstract

Adams , H.-P. and Koziol, J.A. Klassifikation von N. medianus somatosensibel evozierten Potentialen nach Reizraten : Ein Update mit Variation der Signalvorverarbeitung, Netztopologie, Lernalgorithem und Ausgabecodierung, sowie Kreuzvalidierung und Vergleich mit der Diskriminazanalyse. In A. Zell, ed. Workshop: Simulation Neuronaler Netze mit SNNS 1993. Fakultt fr Informatik, Universitt Stuttgart. 1993.

Adams , H.-P. and Koziol, J.A. Klassifikation der Bindungsreaktion von Polypeptiden an Klasse I Molekle des Haupthistokompatibilittskomplexes. In A. Zell, ed. Workshop: Simulation Neuronaler Netze mit SNNS 1993. Fakultt fr Informatik, Universitt Stuttgart, 1993.

Tuckwell, H.C. and Koziol, J.A. A meta-analysis of homovanillic acid concentrations in schizophrenia. Int. J. Neurosci. 73:109-114, 1993. Abstract

Tuckwell, H.C. and Koziol, J.A. World and regional populations. Biosystems 31:59-63, 1993. Abstract

Tsai, K.T. and Koziol, J.A. Score and Wald tests for the multivariate growth curve model with missing data and a patterned covariance matrix. Commun. Statist. Theor. Meth. 22:311-317, 1993.

Bernstein, E.F., Kaplan, J.H., Scala, T.E. Koziol, J.A. and Dilley, R.B. Chat analysis of the influence of specific risk factors on late results after carotid endarterectomy. Curr. Crit. Prob. Vasc. Surg. 5:391-402, 1993. Abstract

Beutler, E., Figueroa, M. and Koziol, J. Treatment of Gaucher's disease. New Engl. J. Med. 328:1567, 1993.

Koziol, J.A., Clark, D.C., Gittes, R.F., and Tan, E.M. The natural history of interstitial cystitis: a survey of 374 patients. J. Urol. 149:465-469, 1993. Abstract

Koziol, J.A. On the optimality of Bayes test statistics and Fisher's combination procedure. In J.K. Ghosh, S.K. Mitra, K.R. Parthasarathy, and B.L.S. Prakasa Rao, eds. Statistics and Probability: A Raghu Raj Bahadur Festschrift. Wiley Eastern Limited, New Delhi, 1993, pp. 365-370.

Koziol, J.A. Probability plots for assessing multivariate normality. The Statistician 42:161-173, 1993.

Koziol, J.A., Erman, M., Pasche, B., Hajdukovic, R. and Mitler, M.M. Assessing a changepoint in a sequence of repeated measurements with application to a low-energy emission therapy sleep study. J. Appl. Statist. 20:393-400, 1993.

Koziol, J.A., Decker, D.J., Boyle, N.A. and Klinman, N. R. The use of Bayesian analysis of PCR-derived genomic DNA sequences to enable a biologically relevant interpretation of immunoglobulin variable region gene expression. J. Theor. Biol. 160:387-398, 1993. Abstract

Adams , H.-P., Koziol, J.A., Elsner, G. and Schinkmann, M. Klassifikation von N. medianus somatosensibel evozierten Potentialen nach Reizraten mit einem neuronalen Netz. In A. Zell, ed. Workshop: Simulation Neuronaler Netze mit SNNS 1992. Fakultt fr Informatik, Universitt Stuttgart, 1992.

Tuckwell, H.D. and Koziol, J.A. World population. Nature 359:200, 1992. Abstract

Bernstein, E.F., Kaplan, J.H., Scala, T.E., Koziol, J.A. and Dilley, R.B. Chat analysis of specific risk factors on late results after carotid endarterectomy. J. Vasc. Surg. 16:575-587, 1992. Abstract

Nassif, X., Mathison, J.C., Wolfeson, E., Koziol, J.A., Ulevitch, R.J. and So, M. Tumor necrosis factor alpha antibody protects against lethal meningococcemia. Molecular Microbiology 6:591-597, 1992. Abstract

Figueroa, M.D., Rosenbloom, B.E., Kay, A.C. et al. A less costly regimen of algucerase to treat Gaucher's disease. New Engl. J. Med. 327:1632-1636, 1992. Abstract

Hollen, C.W., Henthorn, J., Koziol, J.A. and Burstein , S.A. Serum interleukin-6 levels in patients with thrombocytosis. Leukemia and Lymphoma 8:235-241, 1992. Abstract

Dillman, R.O. and Koziol, J.A. Phase I cancer trials: limitations and implications. Mol. Biother. 4:117-121, 1992. Abstract

Koziol, J.A. and Hacke, W. A bivariate version of Andrews plots. IEEE Trans. Biomed. Eng. 38:1271-1274, 1991. Abstract

Koziol, J.A. On maximally selected chi-square statistics. Biometrics 47:1557-2561, 1991.

Koziol, J.A. A note on efficient estimation of mutation rates using Luria-Delbrck fluctuation analysis. Mutation Research 249:275-280, 1991. Abstract

Koziol, J.A. On the occurrence of transcriptional regions in human genomic DNA. J. Theor. Biol. 149:377-380, 1991.

Koziol, J.A. A nonparametric approach to the analysis of multiple endpoints. Biometrie und Informatik 22:44-47, 1991.

Bernstein, E.F., Harker, L.A., Gent, M., Koziol, J.A., and The San Diego Restenosis Group. Preoperative aspirin and dipyridamole in the prevention of carotid artery restenosis: a controlled trial. Curr. Crit. Prob. Vasc. Surg. 3:416-419, 1991.

Hollen, C.W., Henthorn, J., Koziol, J.A. and Burstein, S.A. Elevated serum interleukin-6 levels in patients with reactive thrombocytosis. Brit. J. Haematol. 79:286-290, 1991. Abstract

Decker, D.J., Boyle, N.E., Koziol, J.A. and Klinman, N.R. The expression of the immunoglobulin heavy chain repertoire in developing bone marrow B lineage cells. J. Immunol. 146:350-361, 1991. Abstract

Del Zoppo, G.J., Anderchek, K.E., Koziol, J.A., Copeland, B.R., and Hacke, W. Intracerebral hemorrhage and infarction volume following recombinant tissue plasminogen activator in an acute stroke model. In W. Hacke et al., eds. Thrombolytic Therapy in Acute Ischemic Stroke. Springer-Verlag, Berlin, 1991, pp.259-261.

Koziol, J.A. Multivariate growth curve analyses II. Missing data. In D. Krewski and C. Franklin, eds. Statistics in Toxicology. Gordon and Breach, New York, 1991, pp. 519-534.

Koziol, J.A. Multivariate growth curve analyses I. The Potthoff-Roy model. In D. Krewski and C. Franklin, eds. Statistics in Toxicology. Gordon and Breach, New York, 1991, pp. 499-518.

Koziol, J.A. On the span comparison matrix method for comparing protein or gene sequences. Biometrie und Informatik 21:126-131, 1990.

Koziol, J.A. Cluster analysis of antigenic profiles of tumors: selection of number of clusters using AIC. Meth. Inform. Med. 20:200-204, 1990. Abstract

Koziol, J.A. and Hacke, W. Multivariate data reduction by principal components, with application to neurological scoring instruments. J. Neurol. 237:431-434, 1990. Abstract

Del Zoppo, G.J., Copeland, B.R., Anderchek, K., Hacke, W. and Koziol, J.A. Hemorrhagic transformation following tissue plasminogen activator in experimental cerebral infarction. Stroke 21:596-601, 1990. Abstract

Mitler, M.M., Hajdukovic, R., Erman, M. and Koziol, J. A. Narcolepsy. Journal of Clinical Neurophysiology 7:C1-C26, 1990. Abstract

1985 - 1989

Koziol, J.A. A note on plots of P-values to evaluate many tests simultaneously. Biom. J. 31:969-972, 1989.

Koziol, J.A. Determination of monoclonality from sequential dilution assays. Computer Methods and Programs in Biomedicine 29:173-178, 1989.

Koziol, J.A. A modification of Watson's statistic for goodness of fit. Commun. Statist. Theor. Meth. 18:3739-3747, 1989.

Koziol, J.A. A note on measures of multivariate kurtosis. Biom. J. 31:619-624, 1989.

Koziol, J.A. Multivariate tests for non-additivity. Statistical Papers 30: 27-37, 1989.

Sobel, D.F., Rowe, R., Zyroff, J., Koziol, J.A., Frost, F. and Krupsaw, J. Adverse reactions to iopamidol and iohexol myelography: role of myelographic technique. Headache 29:519-522, 1989. Abstract

Beutler, E., Gelbart, T., Han, J., Koziol, J.A. and Beutler, B. Evolution of the genome and genetic code: Selection at the dinucleotide level by methylation and polyribonucleotide cleavage. Proc. Natl. Acad. Sci. USA 86:192-196, 1989. Abstract

Angell, W.M., Oury, J.H., Lamberti, J.J. and Koziol, J.A. Durability of the viable aortic allograft. J. Thorac. Cardiovasc. Surg. 98:48-56, 1989. Abstract

Shawler, D.L., Johnson, D.E., Koziol, J.A. and Dillman, R.O. Preclinical trials using an immunoconjugate of T101 and methotrexate in an athymic mouse/human T cell tumor model. Journal of Biological Response Modifiers 7:608-618, 1988. Abstract

Dillman, R.O., Johnson, D.E., Shawler, D.L. and Koziol, J.A. Superiority of an acid-labile daunorubicin-monoclonal antibody immunoconjugate compared to free drug. Cancer Research 48:6097-6102, 1988. Abstract

Dillman, R.O., Koziol, J.A. and Shawler, D.L. Mathematical modeling for antibody therapy in the setting of antigenic modulation. Molecular Biotherapy 1:46-52, 1988. Abstract

Koziol, J.A., Petkau, A.J. and Taetle, R. Objective criteria for in vitro drug response in human tumor colony forming assays. Medical Decision Making 8:304-309, 1988. Abstract

Koziol, J.A. Selection of monoclonal cell lines from sequential dilution assays III. J. Immunol. Meth. 114:275-276, 1988.

Koziol, J.A., Perlman, M.D. and Rasmussen, U.A. Combining independent F tests. Technical Report No. 129, Department of Statistics, University of Washington, 1988.

Koziol, J.A. Orthogonal components in MANOVA with application to an anesthesiology experiment. Biom. J. 30:787-793, 1988.

Tsai, K.T. and Koziol, J.A. Varcov II: A computer program for the multivariate analysis of growth and response curves. Computer Methods and Programs in Biomedicine 27:69-74, 1988. Abstract

Tsai, K.T. and Koziol, J.A. Score and Wald tests for the multivariate growth curve model with missing data. Ann. Inst. Statist. Math. 40:179-186, 1988.

Tsai, K.T. and Koziol, J.A. A correlation-type statistic for assessing multivariate normality. Commun. Statist. Simula. 12:637-651, 1988.

Angell, W.W., Oury, J.H., Koziol, J.A. and Dussault, M.H. Survival of aortic allografts containing living cells. In A.C. Yankah et al., eds. Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Substitutes. Steinkopff Verlag Darmstadt, 1988, pp. 273-280.

Oury, J.H., Angell, W.W., and Koziol, J.A. Comparison of Hancock I and Hancock II bioprostheses. J. Cardiac Surg. 3:375-381, 1988. Abstract

Ngo, K.Y., Glotz, V., Koziol, J.A., Lynch, D.C. et al. Homozygous and heterozygous deletions of the von Willebrand factor gene in patients and carriers of severe von Willebrand disease. Proc. Natl. Acad. Sci. USA 85: 2753-2757, 1988. Abstract

Koziol, J.A. Selection of monoclonal cell lines from sequential dilution assays II. Journal of Immunological Methods 107:151-152, 1988. Abstract

Koziol, J.A. Review of Goodness of Fit Techniques, R. B. D'Agostino and M. A. Stephens, eds. Journal of Educational Statistics 12:412-416, 1987.

Koziol, J.A. A note on non-parametric tests for the changepoint problem. Biom. J. 29:791-794, 1987.

Tuckwell, H.C. and Koziol, J.A. Diffusion processes and logistic growth under random dispersal. Bull. Math. Biol. 49:495-506, 1987.

Koziol, J.A., Ferrari, C. and Chisari, F.V. Selection of monoclonal cell lines from sequential dilution assays. Journal of Immunological Methods 105:139-143, 1987. Abstract

Niiya, K., Hodson, E., Bader, R., Byers-Ward, V., Koziol, J. , Plow, E., and Ruggeri, Z.M. Increased surface expression of the membrane glycoprotein IIb/IIIa complex induced by platelet stimulation. Blood 70:475-483, 1987. Abstract

Dillman, R.O. and Koziol, J.A. A mathematical model of monoclonal antibody therapy in leukemia. Mathematical Modelling 9:29-35, 1987. Abstract

Ad Hoc Working Group for Critical Appraisal of the Medical Literature. A proposal for more informative abstracts of clinical articles. Ann. Intern. Med. 106:598-604, 1987. Abstract

Ishibashi, T., Koziol, J.A. and Burstein, S.A. Human recombinant erythropoietin promotes differentiation of murine megakaryocytes in vitro. J. Clin. Invest. 79:286-289, 1987. Abstract

Koziol, J.A. Relative efficiencies of a class of goodness of fit tests for randomly censored data. Biom. J. 29:323-330, 1987.

Koziol, J.A. An alternative formulation of Neyman's smooth goodness of fit tests under composite alternatives. Metrika 34:17-24, 1987.

Koziol, J.A. Stochastic processes in the neurosciences. Journal of Theoretical Neurobiology 5:101-105, 1986.

Dillman, R.O., Shawler, D.L., Johnson, D.E., Meyer , D.L., Koziol, J.A. and Frinke, J.M. Preclinical trials with combinations and conjugates of T101 and doxorubicin. Cancer Research 46:4886-4891, 1986. Abstract

Koziol, J.A. An introduction to multivariate growth curve analyses. Growth 50:259-272, 1986. Abstract

Koziol, J.A. Relative efficiencies of goodness of fit procedures for assessing univariate normality. Ann. Instit. Statist. Math. 38: 485-493, 1986.

Koziol, J.A. Assessing multivariate normality: a compendium. Commun. Statist. Theor. Meth. 15:2763-2783, 1986.

Koziol, J.A. A note on the asymptotic distribution of Mardia's measure of multivariate kurtosis. Commun. Statist. Theor. Meth.15:1507-1513, 1986.

Koziol, J.A. and Tuckwell, H.C. On population projections for Australia and New Zealand. New Zealand Statistician 21:33-38, 1986.

Taetle, R. and Koziol, J.A. In vitro drug testing using hemopoietic cells: goals and limitations. CRC Critical Reviews in Hematology/Oncology 4:169-201, 1985. Abstract

Dillman, R.O. and Koziol, J.A. Mathematical modeling for monoclonal antibody therapy in leukemia. In L. LeCam and R. Olshen, eds. Proceedings of the Berkeley Conference in Honor of Jerzy Neyman and Jack Kiefer,Vol. 1. Wadsworth, 1985, pp. 307-320.

Koziol, J.A. Some statistical issues pertaining to in vitro drug testing with human tumor colony forming assays. Hiroshima Journal of Medicine 34:31-37, 1985. Abstract

Koziol, J.A. A note on testing symmetry with estimated parameters. Statistics and Probability Letters 3:227-230 ,1985.

Crepeau, H., Koziol, J., Reid, N. and Yuh, Y.S. Analysis of incomplete multivariate data from repeated measurement experiments. Biometrics 41:505-514, 1985. Abstract

1980- 1984

Koziol, J.A. and Petkau, A.J. Relative efficiencies of goodness of fit procedures with truncated data. Canadian Journal of Statistics 12:107-117, 1984.

Koziol, J.A. VARCOV: A computer program for the distribution-free analysis of growth and response curves. Computer Programs in Biomedicine 19:69-74, 1984. Abstract

Koziol, J.A. A note on a class of distribution-free tests for growth curves analyses. Zast. Matem. 18:413-425, 1984.

Gallagher, K.P., Matsuzaki, M., Koziol, J.A., Kemper, W.S. and Ross, J. Regional myocardial perfusion and wall thickening during ischemia in conscious dogs. Amer. J. Physiol. 247:H727-H738, 1984. Abstract

Suzuki, K., Pirofsky, B., Koziol, J., Sakatani, T., Yoshimoto, Y. and Fujikura, T. Late A-bomb effects on proliferation and mitotic inhibition of T and B lymphocytes in Adult Health Study subjects in Hiroshima. Technical report, Radiation Effects Research Foundation, Hiroshima , Japan , 1984.

Shea, M., Koziol, J.A. and Howell, S.B. Kinetics of sodium thiosulfate, a cisplatin neutralizer. Clin. Pharmacol. Ther. 35:419-425, 1984. Abstract

Dillman, R.O., Koziol, J.A., Zavanelli, M.T., Beauregard, J.C., Halliburton, B.L., and Royston, I. Immunoincompetence in cancer patients - assessment by in vitro stimulation tests and quantification of lymphocyte subpopulations. Cancer 53:1484-1491, 1984. Abstract

Green, M.R., Young, J.A., Johnson, A., Kroener, J., Koziol , J.A., Saltzstein, S., Yon, J.L., Campbell, T. and Lucas, W. Alternating combination chemotherapy for Stage III and IV ovarian carcinoma. J. Clin. Oncol. 2:1317-1320, 1984. Abstract

Koziol, J.A. Tests for symmetry about an unknown value based on the empirical distribution function. Commun. Statist. Theor. Meth. 12:2823-2846, 1983.

Koziol, J.A. On assessing multivariate normality. J. Roy. Statist. Soc. Ser. B 45:358-361, 1983.

Perlman, M.D., Koziol, J.A. and Rasmussen, U.A. Bayes procedures for combining independent F tests. In S. Karlin, T. Amemiya and L. A. Goodman, eds. Studies in Econometrics, Time Series, and Multivariate Statistics. Academic Press, New York, 1983, pp. 505-528.

Gilpin, E.A., Koziol, J.A., Madsen, E.B., Henning, H. and Ross, J. Jr. Periods of differing mortality distribution during the first year following acute myocardial infarction. American Journal of Cardiology 52:240-244, 1983. Abstract

Byfield, J.E., Stanton, W., Sharp, T.R., Frankel, S.S. and Koziol, J.A. Phase I-II study of 120-hour infused 5-fluorouracil and split-course radiation therapy in localized non-small cell lung cancer. Cancer Treatment Reports 67:933-936, 1983.

Halpern, S.E., Hagan, P.L., Garver, P.R., Koziol, J.A., Chen, A.W.N., Frincke, J.M., Bartholomew, R.M., David, G.S., and Adams, T.H. Stability characterization and kinetics of 111-Indium labeled antitumor antibodies in normal animals and nude mouse-human tumor models. Cancer Research 43:5347-5355, 1983. Abstract

Taetle, R., Calives, A. and Koziol, J.A. Response of human myeloid leukemia cells to various sources of colony stimulating activity and PHA-conditioned medium. Cancer Research 43:2350-2357, 1983.

Dillman, R.O. and Koziol, J.A. Statistical approach to immunosuppression classification using lymphocyte surface markers and functional assays. Cancer Research 43:417-421, 1983. Abstract

Jalowayski, A.A., Yuh, Y.S., Koziol, J.A. and Davidson, T.J. Surgery for nasal obstruction - evaluation by rhinomanometry. Laryngoscope 93:341-345, 1983. Abstract

Brown, C.C. and Koziol, J.A. Statistical aspects of the estimation of human risk from suspected environmental carcinogens. SIAM Review 25:151-181, 1983.

Koziol, J.A. and Yuh, Y.S. Omnibus two sample test procedures with randomly censored data. Biom. J. 24:743-750, 1982.

Koziol, J.A. Orthogonal components of the Kruskal-Wallis and related k-sample linear rank statistics. Biom. J. 24:445-455, 1982.

Koziol, J.A. A class of invariant procedures for assessing multivariate normality. Biometrika 69:423-427, 1982.

Koziol, J.A. and Maxwell, D.A. A distribution-free test for paired growth curve analyses with application to an animal tumor immunotherapy experiment. Statistics in Medicine 1:83-89, 1982. Abstract

Koziol, J.A. and Tuckwell, H.C. Matrix methods for predicting Australia 's population. Function 6:11-14, 1982.

Gerber, K.H., Higgins, C.B., Yuh, Y.S. and Koziol, J.A. Regional myocardial hemodynamic and metabolic effects of ionic and nonionic contrast media in the normal and ischemic state. Circulation 65:1307-1314, 1982. Abstract

Gallagher, K.P., Osakada, G., Hess, O.M., Koziol, J.A., Kemper, W.S. and Ross, J.J. Subepicardial segmental function during coronary stenosis and the role of myocardial fiber orientation. Circulation Research 50:352-359 1982. Abstract

Taetle, R., Howell, S.B., Giuliani, F.C., Koziol, J.A. and Koessler, A. Comparison of the activity of doxorubicin analogues using colony forming assays and human xenografts. Cancer 50:l456-l462, l982. Abstract

Dillman, R.O., Taetle, R., Seagren, S., Royston, I. , Koziol, J.A., and Mendelsohn, J. Extensive disease small cell carcinoma of the lung: trial of non-cross resistant chemotherapy and consolidation radiotherapy. Cancer 49:2003-2008, l982.

Fukushima , M., Colmerauer, M.E.M., Nayak, S.K., Koziol, J.A. and Pilch, Y.S. Antitumor effect of syngeneic spleen cells treated with immune RNA and tumor antigen. Int. J. Cancer 29:113-117, 1982. Abstract

Fukushima , M., Colmerauer, M.E.M., Nayak, S.K., Koziol, J.A. and Pilch, Y.S. Immunotherapy of a murine colon cancer with syngeneic spleen cells, immune RNA and tumor antigen. International Journal of Cancer 29:107-112, 1982. Abstract

Koziol, J.A., Maxwell, D.A., Fukushima, M., Colmerauer, M.E.M., and Pilch, Y.H. A distribution-free test for tumor-growth curve analyses with application to an animal tumor immunotherapy experiment. Biometrics 37:383-390, 1981. Abstract

Joe, H., Koziol, J.A. and Petkau, A.J. Comparison of procedures for testing the equality of survival distributions. Biometrics 37:327-340, 1981. Abstract

Koziol, J.A. and Smith, C.I. A multivariate generalization of the Friedman rank test with application to a problem in molecular biology. Biom. J. 22:683-688, 1980.

Gallagher, K.P., Kumada, T., Koziol, J.A., McKown, M.D., Kemper, W.S., and Ross, J. Significance of regional wall thickening abnormalities relative to transmural myocardial perfusion in anesthetized dogs. Circulation 62:1266-1274, 1980. Abstract

Mushinski, J.F., Koziol, J.A. and Marini, M. Cluster analysis of aminoacyl-tRNAs from mouse plasmacytomas correlates chromatographic profiles with myeloma protein similarity, clonal origin of tumor lines, and the neoplastic nature of the tissues. Journal of Theoretical Biology 85:507-521, 1980. Abstract

Koziol, J.A., Springer, W.R. and Barondes, S.H. Statistical methods of analysis of cohesive specificity among cellular slime molds. Experimental Cell Research 128:375-381, 1980. Abstract

Koziol, J.A. Percentage points of the asymptotic distributions of one and two sample Kuiper statistics for truncated or censored data. Technometrics 22:437-440, 1980.

Colmerauer, M.E.M., Koziol, J.A. and Pilch, Y.H. Enhancement of metastasis development by BCG immunotherapy. Journal of Surgical Oncology 15:235-241, 1980. Abstract

Koziol, J.A. Goodness of fit tests for randomly censored data. Biometrika 67:693-696, 1980.

Koziol, J.A. A note on limiting distributions for spacings statistics. Zeitschrift fr Wahrscheinlichkeitstheorie und verwandte Gebiete 51:55-62, 1980.

Koziol, J.A. On a Cramer-von Mises type statistic for testing symmetry. J. Amer. Statist. Assoc. 75:161-167, 1980.

1975 - 1979

Koziol, J.A. A smooth test for bivariate independence. Sankhya Ser. B 4l:260-269, l979.

Koziol, J.A. Asymptotic normality of multivariate linear rank statistics under general alternatives. Apl. Math. 24:326-347, 1979.

Koziol, J.A. and Nemec, A.F. On a Cramer-von Mises type statistic for testing bivariate independence. Canad. J. Statist. 7:43-52, 1979.

Koziol, J.A. A test for bivariate symmetry based on the empirical distribution function. Commun. Statist. Theor. Meth. 8:207-221, 1979.

Koziol, J.A. Multivariate signed rank statistics for shift alternatives. Mathematische Operationsforschung und Statistik 9:549-562,1978.

Koziol, J.A. and Petkau, A.J. Sequential testing of the equality of two survival distributions using the modified Savage statistic. Biometrika 65:615-623, 1978.

Koziol, J.A. and Perlman, M.D. Combining independent chi-squared tests. J. Amer. Statist. Assoc. 73:753-763, 1978. (Abridged version of Technical Report No. 19, Department of Statistics, University of Chicago, 1976.)

Koziol, J.A. A two sample Cramer-von Mises statistic for randomly censored data. Biom. J. 20:619-624, 1978.

Koziol, J.A., Reid, N., and Levitt, M.H. A simple nonparametric test for trend: an example based on a biological model for cancer of the pancreas. Biom. J. 20:517-523, 1978.

Koziol, J.A. and Reid, N. On multiple comparisons among k populations differing by scale parameters. Mathematische Operationsforschung und Statistik 9:179-184, 1978.

Koziol, J.A. and Tuckwell, H.C. Estimation and analysis of synaptic densities and their spatial variation on the cat motoneuron surface. Brain Research 150:617-624, 1978. Abstract

Koziol, J.A. Exact slopes of certain multivariate tests of hypotheses. Ann. Statist. 6:546-558, 1978.

Koziol, J.A. On goodness of fit tests based on the empirical distribution function for uniform spacings. J. Roy. Statist. Soc. Ser. B 39:333-336, 1977.

Koziol, J.A. and Reid, N. On the asymptotic equivalence of two ranking methods for K sample linear rank statistics. Annals of Statistics 5:1099-1106, 1977.

Koziol, J.A. and Reid, N. On multiple comparisons among K samples subject to unequal patterns of censorship. Commun. Statist. Theor. Meth. 6:1149-1164, 1977.

Halperin, M., Ware, J.H., Byar, D.P., Mantel, N., Brown, C.C., Koziol, J.A., Gail M., and Green, S.B. Testing for interaction in an IxJxK contingency table. Biometrika 64:271-275, 1977.

Koziol, J.A. and Green, S.B. A Cramer-von Mises statistic for randomly censored data. Biometrika 63:466-474, 1976.

Koziol, J.A. and Byar, D.P. Percentage points of the asymptotic distributions of one and two sample K-S statistics for truncated or censored data. Technometrics 17:507-510, 1975.

Books

Koziol, J.A. Handbook of Percentage Points of the Inverse Gaussian Distribution. CRC Press, Boca Raton, 1989. ISBN: 0849336260

L. LeCam and R. Olshen, eds. Proceedings of the Berkeley Conference in Honor of Jerzy Neyman and Jack Kiefer, Volumes I, II. Wadsworth, 1985. (assistant editor)