Source: Interfolio F180

Kurt Wuthrich

Cecil H. and Ida M. Green Professor of Structural Biology
Department of Integrative Structural and Computational Biology


Scripps Research Joint Appointments

Skaggs Graduate School of Chemical and Biological Sciences

Research Focus

For 50 years, Wuthrich groups at the ETH Zurich, Zurich, Switzerland, at Scripps Research, La Jolla, CA, USA and at the iHuman Institute of ShanghaiTech University, Shanghai, China have worked on nuclear magnetic resonance spectroscopy (NMR) with biological macromolecules. Contributions include the method for macromolecular structure determination with NMR in solution and the use of the principles of transverse relaxation-optimized spectroscopy (TROSY) for NMR experiments with large supramolecular assemblies. Applications over the years were focused on differentiation in higher organisms, immune suppression and neuropathology. As of April 2019, research using NMR techniques is continued at ShanghaiTech University, with a focus on trans-membrane signal transfer by G protein-coupled receptors (GPCRs). At Scripps Research and the ETH Zurich, projects on the general theme 'healthcare in the ageing human societies of the 21st century' are pursued, mainly considering the impact of sarcopenia on the human healthspan.


Lizentiat, in chemistry, physics and mathematics, University of Bern, Switzerland
Ph.D., Chemistry (Prof. S. Fallab); Eidgenössisches Turn- und Sportlehrerdiplom, University of Basel, Switzerland
Postdoctoral Training, (Prof. S. Fallab), University of Basel, Switzerland
Postdoctoral Training, (Prof. R.E. Connick), University of California, Berkeley, CA, USA

Professional Experience

1967–69, Bell Telephone Laboratories, Murray Hill, N.J., USA: Member Technical Staff, Biophysics Department (Dr. R.G. Shulman)

1969–present, ETH Zurich, Zurich, Switzerland: Privatdozent (70), Assistant Professor (72), Associate Professor (76), Professor of Biophysics (80); Chairman Biology Department (95–2000)

2001–04, The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Visiting Professor of Structural Biology

2004–present, The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Professor of Structural Biology

Visiting Faculty Appointments 

1988, November: Visiting Miller Research Professor, University of California, Berkeley, CA, USA.

1992, February–March: Scholar in Residence, Johns Hopkins University, Baltimore, MD, USA.

1994, February–June: Sherman Fairchild Distinguished Scholar, Caltech, Pasadena, CA, USA.

1994, October–December: Guest Scientist, The Scripps Research Institute, La Jolla, CA, USA.

1995, February–April: Visiting Associate in Biology and Chemistry, Caltech, Pasadena, CA, USA.

1997–1998, For two months: Institute of Physical and Chemical Research (RIKEN), Tokyo, Japan.

1997–2000, Visiting Professor, Dept. of Chemistry, University of Edinburgh, Edinburgh, UK.

2006–2008, Underwood International College Distinguished Professor, Yonsei University, Seoul, Korea.

2006–present, Honorary Professor of Science, Chinese University of Hong Kong, Hong Kong.

2009–2013, WCU Distinguished Professor, Yonsei University, Seoul, Korea.

2011–present, Honorary Visiting Professor, Universität Duisburg–Essen, Germany.

2012–2016, Pesquisador Visitante Especial, Universidade Federal do Rio de Janeiro, Brazil.

2013–present, Distinguished Senior Professor, iHuman Institute, ShanghaiTech University, Shanghai, China.

2014–present, Adjunct Distinguished Professor, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Korea.


Wüthrich Wins 2002 Nobel Prize in Chemistry

Wüthrich ETH Zürich Group

iHuman Institute at ShanghaiTech University

Complete List of Publications

Awards & Professional Activities

1987 Deutsche Akademie der Naturforscher Leopoldina
1990 Stein and Moore Award of the Protein Society, USA
1991 Gilbert Newton Lewis Medal, University of California, Berkeley, USA
1991 Louisa Gross Horwitz Prize, Columbia University, New York, USA
1992 Marcel Benoist-Preis, awarded by the Swiss Confederation
1992 Foreign Associate, US National Academy of Sciences
1993 Prix Louis Jeantet de Médecine
1996 Kaj Linderstrøm-Lang Prize, Carlsberg Foundation, Copenhagen, Denmark
1997 Dottore ad Honorem in Chimica, Università degli Studi di Siena, Italy
1997 Dr. phil. honoris causa, Universität Zürich, Switzerland
1998 Kyoto Prize in Advanced Technology
1999 Günther Laukien Prize, Experimental NMR Conference (ENC), USA
1999 Otto-Warburg-Medaille, Gesellschaft für Biochemie und Molekularbiologie, Germany
2000 Associé étranger, Académie des Sciences, Institut de France
2001 Docteur honoris causa, Ecole Polytechnique Fédérale de Lausanne, Switzerland 2002 Schweizerische Akademie der Medizinischen Wissenschaften (SAMW)
2002 Nobel Prize in Chemistry
2003 Honorary Member, Swiss Chemical Society
2004 Doctor honoris causa, Universitat de València, Spain
2004 Doctor of Science honoris causa, University of Sheffield, UK
2005 Doctor of Science honoris causa, King George's Medical University, Lucknow, India
2007 Doctor of Medicine honoris causa, University of Pécs, Hungary
2007 Doctor honoris causa, Lomonosov Moscow State University, Moscow, Russia
2007 Docteur honoris causa, Université René Descartes, Paris, France
2007 Laurea Specialistica in Biotechnology honoris causa, University of Verona, Italy
2008 Paul Walden Medal, Riga Technical University, Riga, Latvia
2009 Jabir ibn Hyyan (Geber) Medal, Saudi Chemical Society, Saudi Arabia
2010 Ralph and Helen Oesper Award, University of Cincinnati, Cincinnati, OH, USA
2010 Foreign Member, The Royal Society, UK
2010 Laurea Magistrale in Pharmacy honoris causa, Seconda Università degli Studi di Napoli, Italy
2010 Honorary Fellow, The Spanish Biophysical Society
2012 President's Gold Medal, Government of India
2013 Corresponding Member, Academia Brasileira de Ciências
2013 Theodor Bücher Medal, Federation of European Biochemical Societies
2015 Doctor honoris causa in Phamacology, University of Patras, Greece
2015 Doctor honoris causa, Universidad de Buenos Aires, Argentina
2015 IUBMB Medal
2016 Shanghai, 1’000 Talents Award
2016 Doctor honoris causa, Universidad Nacional de Córdoba, Argentina
2017 Genome Valley Excellence Award, BioAsia, Hyderabad, India

Selected Publications

Zhang, J.; Feng, D.; Cheng, J.; Wüthrich, K. Adenosine A Receptor (AAR) Ligand Screening Using the F-NMR Probe FPPA. 2023, 145, 15061-15064.