Source: Interfolio F180
Peter Schultz
Research Focus
Biological Chemistry
Our research program combines the tools and principles of chemistry with the molecules and processes of living cells to synthesize new molecules and molecular assemblies with novel physical, chemical and biological functions. By studying the structure and function of the resulting molecules, new insights can be gained into the mechanisms of complex biological and chemical systems. Active research projects span the interface of biology, chemistry, and materials science, and include:
-The development and application of methods for adding new building blocks to the genetic codes of prokaryotic and eukaryotic organisms
- The application of molecular diversity to problems in biological structure, recognition and catalysis, drug discovery, and materials science
- Chemical and genomics studies of stem cell biology, oncogenesis and orphan/neglected diseases
-Generation and characterization of catalytic antibodies
Education
Ph.D. (Chemistry), California Institute of Technology, 1984B.S. (Chemistry), California Institute of Technology, 1979
Professional Experience
Peter G. Schultz did his undergraduate and graduate work at the California Institute of Technology. In 1985, after postdoctoral studies at the Massachusetts Institute of Technology, he joined the faculty of the University of California at Berkeley, where he was Professor of Chemistry, Principal Investigator at Lawrence Berkeley National Laboratory and an Investigator of the Howard Hughes Medical Institute. Schultz joined the faculty of Scripps in 1999 where he is currently the Scripps Family Professor of Chemistry and President of Scripps.Awards & Professional Activities
1979 Sigma Xi Award, Outstanding Undergraduate Research1983 McKoy Award, Outstanding Graduate Research, CalTech
1984 Nobel Laureate Signature Award, American Chemical Society
1985 Dreyfus Junior Faculty Grantee
1985 Presidential Young Investigator Award, National Science Foundation
1985 Searle Scholar
1986 Eli Lilly Scholar
1988 Alfred P. Sloan Fellow
1988 Alan T. Waterman Award, National Science Foundation
1990 Arthur C. Cope Scholar Award, American Chemical Society
1990 American Chemical Society Award in Pure Chemistry
1990 American Academy of Arts and Sciences
1991 Miller Research Professor, University of California, Berkeley
1991 Eli Lilly Award in Biological Chemistry, American Chemical Society
1991 Fresenius Award of Phi Lambda Upsilon
1991 Ernest Orlando Lawrence Memorial Award, Department of Energy
1992 Humboldt Research Award for Senior U.S. Scientists, Alexander von Humboldt Foundation
1992 DuPont Merck Young Investigator Award, The Protein Society
1992 College of Chemistry Teaching Award, University of California, Berkeley
1992 Ciba-Geigy Drew Award in Biomedical Research, Ciba-Geigy
1993 Harrison Howe Lectureship Award, Rochester Section of the American Chemical Society
1993 National Academy of Sciences, USA
1994 Wolf Prize in Chemistry
1994 Honorary Doctor of Sciences, Uppsala University of Sweden
1995 California Scientist of the Year Award
1996 Discover Magazine Awards for Technological Innovation
1998 Institute of Medicine of the National Academy of Sciences
2001 Alfred Bader Award in Bioorganic or Bioinorganic Chemistry
2001 Caltech Distinguished Alumni Award
2002 Paul Ehrlich-and Ludwig Darmstaedter Prize
2006 Arthur C. Cope Award, American Chemical Society
2009 Hamilton Award
2010 Kirkwood Award
2013 Solvay Prize
2013 American Association for the Advancement of Science Fellow
2013 Nature Biotechnology #1 Translational Researcher
2015 Yale Honorary Doctorate
2015 San Diego Bio-Pharma Achievement Award
2015 Heinrich Wieland Prize
2015 National Academy of Inventors Fellow
2016 ACS Chemical Biology Lecturer Award
2017 Westheimer Medal, Harvard
2019 Tetrahedron Prize
2021 NAS Award in Chemical Sciences, National Academy of Sciences
Selected Publications
Lemke, E. A.; Summerer, D.; Geierstanger, B. H.; Brittain, S. M.; Schultz, P. G. Control of protein phosphorylation with a genetically encoded photocaged amino acid. Nature Chemical Biology 2007, 3, 769-772.
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Gruenewald, J.; Tsao, M. L.; Perera, R.; Dong, L. Q.; Niessen, F.; Wen, B. G.; Kubitz, D.; Smider, V. V.; Ruf, W.; Nasoff, M.; Lerner, R. A.; Schultz, P. G. Immunochemical termination of self-tolerance. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 11276-11280.
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Liu, C. C.; Mack, A. V.; Tsao, M. L.; Mills, J. H.; Lee, H. S.; Choe, H.; Farzan, M.; Schultz, P. G.; Smider, V. V. Protein evolution with an expanded genetic code. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 17688-17693.
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Lee, H. S.; Guo, J. T.; Lemke, E. A.; Dimla, R. D.; Schultz, P. G. Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. Journal of the American Chemical Society 2009, 131, 12921-12923.
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Schultz, P. G.; Schultz, P. G. Synthesis at the Interface of Chemistry and Biology. Chemistry international 2014, 36, 3-8.
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Liu, C. C.; Schultz, P. G. Adding new chemistries to the genetic code. Annual Review of Biochemistry 2010, 79, 413-444.
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