Laurent Mosnier, PhD

Associate Professor
Department of Molecular Medicine
California Campus


Ph.D. (Thrombosis and Hemostasis), Utrecht University, 2001
B.B.A. (Economics), Erasmus University, 1999
M.S. (Medical Biology), Utrecht University, 1997
B.S. (Medical Biology), Utrecht University, 1992

Professional Experience

2005-2017 Assistant Professor, Molecular and Experimental Medicine (MEM), Scripps Research

Selected References

All Publications

Griffin, J. H., Zlokovic, B. V. & Mosnier, L. O. Activated protein C, protease activated receptor 1, and neuroprotection. (2018). Blood, 132(2), 159-169. PMCID: PMC6043978.

Spronk, H. M. H., Padro, T., Siland, J. E., Prochaska, J. H., Winters, J., van der Wal, A. C., Posthuma, J. J., Lowe, G., d'Alessandro, E., Wenzel, P., Coenen, D. M., Reitsma, P. H., et al. Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis. (2018). Thrombosis and Haemostasis, 118(2), 229-250.

Sinha, R. K., Wang, Y., Zhao, Z., Xu, X., Burnier, L., Gupta, N., Fernandez, J. A., Martin, G., Kupriyanov, S., Mosnier, L. O., Zlokovic, B. V., Griffin, J. H. PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke. (2018). Blood, 131(11), 1163-1171. PMCID: PMC5855020.

Cooke, E. J., Zhou, J. Y., Wyseure, T., Joshi, S., Bhat, V., Durden, D. L., Mosnier, L. O. & von Drygalski, A. Vascular permeability and remodelling coincide with inflammatory and reparative processes after joint bleeding in factor VIII-deficient mice. (2018). Thrombosis and Haemostasis, 118(6), 1036-1047.

Mosnier, L. O. Warfarin, a juggler's demise. (2018). Blood, 131(25), 2742-2743. PMCID: PMC6014355.

Fernandez, J. A., Xu, X., Sinha, R. K., Mosnier, L. O., Sanner, M. F. & Griffin, J. H. Activated protein C light chain provides an extended binding surface for its anticoagulant cofactor, protein S. (2017). Blood Advances, 1(18), 1423-1426. PMCID: PMC5727852.

Griffin, J. H., Mosnier, L. O., Fernandez, J. A. & Zlokovic, B. V. 2016 Scientific Sessions Sol Sherry Distinguished Lecturer in Thrombosis. Thrombotic stroke: neuroprotective therapy by recombinant-activated protein C. (2016). Arteriosclerosis Thrombosis and Vascular Biology, 36(11), 2143-2151. PMCID: PMC5119536.

Wyseure, T., Mosnier, L. O. & von Drygalski, A. Advances and challenges in hemophilic arthropathy. (2016). Seminars in Hematology, 53(1), 10-19. PMCID: PMC5034876.

Sinha, R. K., Yang, X. V., Fernandez, J. A., Xu, X., Mosnier, L. O. & Griffin, J. H. Apolipoprotein E receptor 2 mediates activated protein C-induced endothelial Akt activation and endothelial barrier stabilization. (2016). Arteriosclerosis Thrombosis and Vascular Biology, 36(3), 518-524. PMCID: PMC4816599.

Cramer, T. J., Anderson, K., Navaz, K., Brown, J. M., Mosnier, L. O. & von Drygalski, A. Heterozygous congenital Factor VII deficiency with the 9729de14 mutation, associated with severe spontaneous intracranial bleeding in an adolescent male. (2016). Blood Cells Molecules and Diseases, 57, 8. PMCID: PMC4874642.