Mansun Law, PhD
Scripps Research Joint Appointments
Education
D.Phil. (Virology), University of Oxford, Sir William Dunn School of Pathology, 2001M.Phil. (Molecular Biology), The University of Hong Kong, Department of Zoology, 1997
B.Sc., The University of Hong Kong, Faculty of Science, 1995
Professional Experience
2014-2017 Associate Professor, Immunology and Microbial Science (IMS), Scripps Research2008-2014 Assistant Professor, Immunology and Microbial Science (IMS), Scripps Research
2004-2008 Research Associate and Senior Research Associate with Dr. Dennis R. Burton, Immunology and Microbial Science (IMS), Scripps Research
2001-2004 Postdoctoral Fellow with Dr. Geoffrey L. Smith, Imperial College London
Selected References
Salas, J. H., Urbanowicz, R. A., Guest, J. D., Frumento, N., Figueroa, A., Clark, K. E., Keck, Z., Cowton, V. M., Cole, S. J., Patel, A. H., Fuerst, T. R., Drummer, H. E., et al. An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development. (2022). Gastroenterology, 162(2), 562-574. PMCID: PMC8792218.
Yechezkel, I., Law, M. & Tzarum, N. From Structural Studies to HCV Vaccine Design. (2021). Viruses-Basel, 13. PMCID: PMC8147963.
Chen, F., Tzarum, N., Lin, X., Giang, E., Velazquez-Moctezuma, R., Augestad, E. H., Nagy, K., He, L. L., Hernandez, M., Fouch, M. E., Grinyo, A., Chavez, D., et al. Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins. (2021). Immunity, 54(4), 781-796. PMCID: PMC8046733.
Law, M. Antibody Responses in Hepatitis C Infection. (2021). Cold Spring Harbor Perspectives in Medicine, 11. PMCID: PMC7919400.
Gebert, L. F. R., Law, M. & Macrae, I. J. A structured RNA motif locks Argonaute2:miR-122 onto the 5' end of the HCV genome. (2021). Nature Communications, 12. PMCID: PMC8616905.
Zhang, H., Chen, F., Giang, E., Bao, F., Lauer, G. M., Marsh, C., Law, M. & Pockros, P. J. Virus reactivation in a non-cirrhotic HBV patient requiring liver transplantation after cessation of nucleoside analogue therapy. (2021). Antiviral Therapy, 26(1-2), 3-8.
Belz, Tyson F., Olson, Margaret E., Giang, Erick, Law, M. & Janda, K. Evaluation of a Series of Lipidated Tucaresol Adjuvants in a Hepatitis C Virus Vaccine Model. (2020). ACS Medicinal Chemistry Letters, 11(12), 2428-2432. PMCID: PMC7734796.
Chen, F., Lairson, L. L. & Law, M. Into the Unknown: A Chemical Biology Approach Provides Mechanistic Insight into HCV Entry. (2020). Cell Chemical Biology, 27(7), 767-769.
Tzarum, N., Giang, E., Kadam, R. U., Chen, F., Nagy, K., Augestad, E. H., Velazquez-Moctezuma, R., Keck, Z. Y., Hua, Y. Z., Stanfield, R. L., Dreux, M., Prentoe, J., et al. An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. (2020). Science Advances, 6. PMCID: PMC7380959.
He, L. L., Tzarum, N., Lin, X. H., Shapero, B., Sou, C., Mann, C. J., Stano, A., Zhang, L., Nagy, K., Giang, E., Law, M., Wilson, I. A., et al. Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. (2020). Science Advances, 6. PMCID: PMC7159917.