Taisuke Kanaji, MD, PhD

Institute Investigator
Department of Molecular Medicine
California Campus


Ph.D. (Hematology), Kyushu University, 1999
M.D., Kyushu University, 1990

Professional Experience

2016-2017 Assistant Professor of MEM, Molecular and Experimental Medicine (MEM), Scripps Research
2008-2016 Research Scientist, BloodCenter of Wisconsin
2006-2008 Assistant Professor, Kurume University School of Medicine (Japan)
2000-2003 Research Associate, Scripps Research

Selected References

All Publications

Kanaji, T., Vo, M. N., Kanaji, S., Zarpellon, A., Shapiro, R., Morodomi, Y., Yuzuriha, A., Eto, K., Belani, R., Do, M. H., Yang, X. L., Ruggeri, Z. M., et al. Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia. (2018). Proceedings of the National Academy of Sciences of the United States of America, 115(35), EB228-EB235. PMCID: PMC6126720.

Takata, Y., Seki, R., Kanaji, T., Nohara, M., Koteda, S., Kawaguchi, K., Nomura, K., Nakamura, T., Morishige, S., Oku, E., Osaki, K., Hashiguchi, E., et al. Association between thromboembolic events and the JAK2 V617F mutation in myeloproliferative neoplasms. (2014). Kurume Medical Journal, 60(3-4), 89-97.

Kanaji, T., Kanaji, S., Montgomery, R. R., Patel, S. B. & Newman, P. J. Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia. (2013). Blood, 122(15), 2732-2742. PMCID: PMC3795464.

Kanaji, T., Ware, J., Okamura, T. & Newman, P. J. GPIbα regulates platelet size by controlling the subcellular localization of filamin. (2012). Blood, 119(12), 2906-2913. PMCID: PMC3327465.

Takata, Y., Kanaji, T., Moroi, M., Seki, R., Sano, M., Nakazato, S., Sueoka, E., Imamura, Y. & Okamura, T. Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen. (2012). International Journal of Hematology, 96(6), 733-742.

Ohtsuka, Y., Kanaji, T., Nish, M., Sakai, N., Sato, T., Aoki, S., Wakayama, K., Nakazato, S., Hisano, S., Sado, Y., Kawachi, H., Izuhara, K., et al. A notable case report of May-Hegglin anomaly with immune complex-related nephropathy: a genetic and histological analysis. (2011). Clinical Nephrology, 75(3), 255-262.

Jung, S. M., Sonoda, M., Tsuji, K., Jimi, A., Nomura, S., Kanaji, T. & Moroi, M. Are integrin alpha(2)beta(1), glycoprotein Ib and vWf levels correlated with their contributions to platelet adhesion on collagen under high-shear flow?. (2010). Platelets, 21(2), 101-111.

Ohtsubo, K., Sata, M., Kawaguchi, T., Morishige, S., Takata, Y., Oku, E., Imamura, R., Seki, R., Hashiguchi, M., Osaki, K., Yakushiji, K., Kanaji, T., et al. Characterization of the light chain-restricted clonal B cells in peripheral blood of HCV-positive patients. (2009). International Journal of Hematology, 89(4), 452-459.

Kanaji, S., Kanaji, T., Honda, M., Nakazato, S., Wakayama, K., Tabata, Y., Shibata, S., Gondo, H., Nakamura, I., Node, K., Miura, M., Miyahara, M., et al. Identification of four novel mutations in F5 associated with congenital factor V deficiency. (2009). International Journal of Hematology, 89(1), 71-75.

Kanaji, S., Kanaji, T., Migita, M., Kunishima, S., Kunicki, T. J., Okamura, T. & Izuhara, K. Characterization of a patient with atypical amegakaryocytic thrombocytopenia. (2008). European Journal of Haematology, 80(4), 361-364.