Source: Interfolio F180


Scott Henderson, PhD

Professor
Director, Core Microscopy Facility
Department of Integrative Structural and Computational Biology


 Email

Research Focus

Scripps Research's Microscopy Core Facility offers electron microscopy, confocal microscopy, multi-photon microscopy, total internal reflection fluorescence (TIRF) microscopy, and ‘super-resolution’ nanoscopy (including MINFLUX, STED, & STORM), along with a full range of services including: collaboration, consultation, experimental design, sample preparation, assistance with imaging & multi-dimensional image analysis, user training, technical support, and assistance with research grant applications.

Links

Scott Henderson joins Scripps as Director of Microscopy Core Facility


Education

Ph.D. (Zoology / Cell Biology), University of Western Ontario, 1990


Professional Experience

2017-Present
Professor, Scripps Research Institute
Director, Microscopy Core Facility

Director, Microscopy Facility, Virginia Commonwealth University
Associate Professor in the Department of Anatomy and Neurobiology

Faculty Member, Mount Sinai School of Medicine, New York


Awards & Professional Activities

2005 National Aeronautics & Space Administration (NASA) - STS-107 Group Achievement Award - STS-107 Life Science Payload Team (MSSM)
1989 Award of Excellence in Graduate Teaching (UWO)
1988 Graduate Research Fellowship (UWO)
1985 Ontario Graduate Scholarship


Selected Publications

Mulhall, Eric M.; Gharpure, Anant; Lee, Rachel M.; Dubin, Adri E.; Aaron, Je S.; Marshall, Kara L.; Spencer, Kath R.; Reiche, Mich A.; Henderson, Scott C.; Chew, Teng- L.; Patapoutian, Ardem Direct observation of the conformational states of PIEZO1. Nature 2023.
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Ross, Patrick; Cid, Tania; Fernández Quintero, Monica; Loeffler, Johannes; Fatima, Hijab; Leaman, Dan P.; Matthias, Jessica; Spencer, Kathryn; Zwick, Michael B.; Henderson, Scott C.; Ward, Andrew B.; Mace, Emily M.; Murin, Charles Danie D. CD16a pairs form the basal molecular subunit for the NK-cell ADCC lytic synapse. 2025.

Johnson, Jennifer L.; Meneses-Salas, Elsa; Ramadass, Mahalakshmi; Monfregola, Jlenia; Rahman, Farhana; Carvalho Gontijo, Raquel; Kiosses, William B.; Pestonjamasp, Kersi; Allen, Dale; Zhang, Jinzhong; Osborne, Dou G.; Zhu, Yanfang P.; Wineinger, Nathan; Askari, Kasra; Chen, Danni; Yu, Juan; Henderson, S C.; Hedrick, Catherine C C.; Ursini, Matilde V.; Grinstein, Sergio; Billadeau, Daniel D D.; Catz, Sergio D. Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation. 2022, 13, 5529.

Deng, Yisong; Hammond, John A.; Pauszek, Raymond; Ozog, Stosh; Chai, Ilean; Rabuck-Gibbons, Jessica; Lamichhane, Rajan; Henderson, S C.; Millar, David P.; Torbett, Bruc E.; Williamson, James R. Discrimination between Functional and Non-functional Cellular Gag Complexes involved in HIV-1 Assembly. 2021, 433, 166842.

Mehta, Angad P.; Supekova, Lubica; Chen, Jian-Hu H.; Pestonjamasp, Kersi; Webster, Paul; Ko, Yeonjin; Henderson, Scott C.; McDermott, Gerry; Supek, Frantisek; Schultz, Peter G. Engineering yeast endosymbionts as a step toward the evolution of mitochondria. 2018, 115, 11796-11801.

Saleh, Tareq; Tyutyunyk-Massey, Liliya; Murray, Graeme F.; Alotaibi, Moureq R.; Kawale, Ajinkya S.; Elsayed, Zeinab; Henderson, Scott C.; Yakovlev, Vasily; Elmore, Lynne W.; Toor, Amir; Harada, Hisashi; Reed, Jason; Landry, Joseph W.; Gewirtz, David A. Tumor cell escape from therapy-induced senescence. 2019, 162, 202-212.

Jiang, Min; Zhang, Mei; Henderson, Scott C.; Gea-ny, Tseng Probing the Trafficking Routes of KCNQ1 and KCNE1 After Their ER Exit. Biophysical Journal 2015, 108, 196a.
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