Scott Henderson, PhD
Professor
Department of Integrative Structural and Computational Biology
Director, Core Microscopy Facility
Research Focus
Scripps Research's Microscopy Core Facility offers electron microscopy, confocal microscopy, multi-photon microscopy, total internal reflection fluorescence (TIRF) microscopy, and ‘super-resolution’ nanoscopy (including MINFLUX, STED, & STORM), along with a full range of services including: collaboration, consultation, experimental design, sample preparation, assistance with imaging & multi-dimensional image analysis, user training, technical support, and assistance with research grant applications.
Links
Scott Henderson joins Scripps as Director of Microscopy Core Facility
Select Publications
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Mulhall, Eric M.; Gharpure, Anant; Lee, Rachel M.; Dubin, Adri E.; Aaron, Je S.; Marshall, Kara L.; Spencer, Kath R.; Reiche, Mich A.; Henderson, Scott C.; Chew, Teng- L.; Patapoutian, Ardem Direct observation of the conformational states of PIEZO1. Nature 2023.
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Ross, Patrick; Cid, Tania; Fernández Quintero, Monica; Loeffler, Johannes; Fatima, Hijab; Leaman, Dan P.; Matthias, Jessica; Spencer, Kathryn; Zwick, Michael B.; Henderson, Scott C.; Ward, Andrew B.; Mace, Emily M.; Murin, Charles Danie D. CD16a pairs form the basal molecular subunit for the NK-cell ADCC lytic synapse. 2025.
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Johnson, Jennifer L.; Meneses-Salas, Elsa; Ramadass, Mahalakshmi; Monfregola, Jlenia; Rahman, Farhana; Carvalho Gontijo, Raquel; Kiosses, William B.; Pestonjamasp, Kersi; Allen, Dale; Zhang, Jinzhong; Osborne, Dou G.; Zhu, Yanfang P.; Wineinger, Nathan; Askari, Kasra; Chen, Danni; Yu, Juan; Henderson, S C.; Hedrick, Catherine C C.; Ursini, Matilde V.; Grinstein, Sergio; Billadeau, Daniel D D.; Catz, Sergio D. Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation. 2022, 13, 5529.
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Deng, Yisong; Hammond, John A.; Pauszek, Raymond; Ozog, Stosh; Chai, Ilean; Rabuck-Gibbons, Jessica; Lamichhane, Rajan; Henderson, S C.; Millar, David P.; Torbett, Bruc E.; Williamson, James R. Discrimination between Functional and Non-functional Cellular Gag Complexes involved in HIV-1 Assembly. 2021, 433, 166842.
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Mehta, Angad P.; Supekova, Lubica; Chen, Jian-Hu H.; Pestonjamasp, Kersi; Webster, Paul; Ko, Yeonjin; Henderson, Scott C.; McDermott, Gerry; Supek, Frantisek; Schultz, Peter G. Engineering yeast endosymbionts as a step toward the evolution of mitochondria. 2018, 115, 11796-11801.
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Saleh, Tareq; Tyutyunyk-Massey, Liliya; Murray, Graeme F.; Alotaibi, Moureq R.; Kawale, Ajinkya S.; Elsayed, Zeinab; Henderson, Scott C.; Yakovlev, Vasily; Elmore, Lynne W.; Toor, Amir; Harada, Hisashi; Reed, Jason; Landry, Joseph W.; Gewirtz, David A. Tumor cell escape from therapy-induced senescence. 2019, 162, 202-212.