Lars Hangartner, PhD

Associate Professor of IMS
Department of Immunology and Microbiology
California Campus


 Email

Education

Ph.D., Eidgenössische Technische Hochschule, 2002
Diploma (Molecular Biology), University of Zurich, 1997

Professional Experience

2015-2017 Associate Professor, Immunology and Microbial Science (IMS), Scripps Research
2009-2015 Professor SNSF, Institute of Medical Virology, University of Zurich
2008-2009 Staff Scientist, University of Zurich
2005-2008 Senior Research Associate, Scripps Research
2002-2005 Postdoctoral Fellow, University Hospital Zurich

Selected References

All Publications

Turman, J. M., Cheplowitz, A. M., Tiwari, C., Thomas, T., Joshi, D., Bhat, M., Wu, Q., Pong, E., Chu, S. Y., Szymkowski, D. E., Sharma, A., Seveau, S., et al. Accelerated Clearance and Degradation of Cell-Free HIV by Neutralizing Antibodies Occurs via Fc gamma RIIb on Liver Sinusoidal Endothelial Cells by Endocytosis. (2021). Journal of Immunology, 206(6), 1284-1296. PMCID: PMC7946731.

Hangartner, L., Beauparlant, D., Rakasz, E., Nedellec, R., Hoze, N., McKenney, K., Martins, M. A., Seabright, G. E., Allen, J. D., Weiler, A. M., Friedrich, T. C., Regoes, R. R., et al. Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates. (2021). Science Translational Medicine, 13. PMCID: PMC8049513.

Nogal, B., Bianchi, M., Cottrell, C. A., Kirchdoerfer, R. N., Sewall, L. M., Turner, H. L., Zhao, F., Sok, D., Burton, D. R., Hangartner, L. & Ward, A. B. Mapping polyclonal antibody responses in non-human primates vaccinated with HIV env trimer subunit vaccines. (2020). Cell Reports, 30(11), 3755-3765. PMCID: PMC7153566.

Pauthner, M. G. & Hangartner, L. Broadly Neutralizing Antibodies to Highly Antigenically Variable Viruses as Templates for Vaccine Design. (2020). Vaccination Strategies against Highly Variable Pathogens. 31-87.

Alter, G., Yu, W. H., Chandrashekar, A., Borducchi, E. N., Ghneim, K., Sharma, A., Nedellec, R., McKenney, K. R., Linde, C., Broge, T., Suscovich, T. J., Linnekin, T., et al. Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques. (2020). Cell, 183(1), 185-196. PMCID: PMC7534693.

Hangartner, L. & Burton, D. R. Vaccination Strategies Against Highly Variable Pathogens Preface. (2020). Vaccination Strategies against Highly Variable Pathogens. V-VI.

Hangartner, L. Public endowment of B cells. (2019). Immunity, 51(4), 601-603.

Voss, J. E., Gonzalez-Martin, A., Andrabi, R., Fuller, R. P., Murrell, B., McCoy, L. E., Porter, K., Huang, D., Li, W., Sok, D., Le, K., Briney, B., et al. Reprogramming the antigen specificity of B cells using genome-editing technologies. (2019). Elife, 8. PMCID: PMC6355199.

Pauthner, M. G., Nkolola, J. P., Havenar-Daughton, C., Murrell, B., Reiss, S. M., Bastidas, R., Prevost, J., Nedellec, R., von Bredow, B., Abbink, P., Cottrell, C. A., Kulp, D. W., et al. Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers. (2019). Immunity, 50(1), 241-252. PMCID: PMC6335502.

Bianchi, M., Turner, H. L., Nogal, B., Cottrell, C. A., Oyen, D., Pauthner, M., Bastidas, R., Nedellec, R., McCoy, L. E., Wilson, I. A., Burton, D. R., Ward, A. B., et al. Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization. (2018). Immunity, 49(2), 288-300. PMCID: PMC6104742.