Department of Integrative Structural and Computational Biology

Faculty

Chunlei Wu, PhD

Associate Professor Tenure
Department of Integrative Structural and Computational Biology

Scripps Research Joint Appointments

Department of Molecular Medicine
Faculty, Graduate Program

Research Focus

We are currently focusing on applying data science methodology and cloud computing technologies to facilitate biomedical discovery, through the large-scale biological data integration.

Education

Ph.D. (Biomathematics and Biostatistics), University of Texas Health Science Center at Houston, 2006

Professional Experience

2017-2017 Associate Professor of Molecular Medicine, Molecular Medicine, Scripps Research
2011-2017 Associate Professor of Molecular Medicine, Molecular and Experimental Medicine (MEM), Scripps Research
2010-2011 Research Investigator II, Genomics Institute of the Novartis Research Foundation (GNF)
2007-2010 Research Investigator I, Genomics Institute of the Novartis Research Foundation (GNF)

Selected References

All Publications

Xin J, Afrasiabi C, Lelong S, Adesara J, Tsueng G, Su AI, Wu C. Cross-linking BioThings APIs through JSON-LD to facilitate knowledge exploration. BMC Bioinformatics. 2018 Feb 1;19(1):30.

Xin J, Mark A, Afrasiabi C, Tsueng G, Juchler M, Gopal N, Stupp GS, Putman TE, Ainscough BJ, Griffith OL, Torkamani A, Whetzel PL, Mungall CJ, Mooney SD, Su AI, Wu C. High-performance web services for querying gene and variant annotation. Genome Biol. 2016 May 6;17(1):91.

Liu X, Wu C, Li C, Boerwinkle E. dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs. Hum Mutat. 2016 Mar;37(3):235-41.

Wu C, Jin X, Tsueng G, Afrasiabi C, Su AI. BioGPS: building your own mash-up of gene annotations and expression profiles. Nucleic Acids Res. 2016 Jan 4;44(D1):D313-6.

Wu C, MacLeod I, Su AI. Su. BioGPS and MyGene.info: organizing online, gene-centric information, Nucleic Acids Res, 41(D1):D561-5 2013.

Wu C, Orozco C, Boyer J, Leglise M, Goodale J, Batalov S, Hodge CL, Haase J, Janes J, Huss JW 3rd and Su AI (2009) BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol, 10:R130.

Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL, Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Saez E, Wiltshire T and Su AI (2008) Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet, 4:e1000070.

Wu C, Zhao H, Baggerly K, Carta R, Zhang L (2007) Short oligonucleotide probes containing G-stacks display abnormal binding affinity on Affymetrix microarrays. Bioinformatics, 23(19):2566-72.

Wu C, Carta R, Zhang L (2005). Sequence dependence of cross-hybridization on short oligo microarrays. Nucleic Acids Res, 33(9):e84.

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