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Bryan Briney, PhD

Professor

Department of Immunology and Microbiology

Bryan Briney, PhD

Research Focus

Multi-omics analyses of the human humoral immune response to infectious diseases including HIV, Lassa, Ebola and SARS-CoV-2.

Select Publications


  • Ben-Othman, R ..; Cai, B.; Liu, A. C.; Varankovich, N.; He, D.; Blimkie, T. M.; Lee, A. H.; Gill, E. E.; Novotny, M.; Aevermann, B.; Drissler, S.; Shannon, C. P.; McCann, S.; Marty, K.; Bjornson, G.; Edgar, R. D.; Lin, D.; Gladish, N.; Maclsaac, J.; Amenyogbe, N.; Chan, Q.; Llibre, A.; Collin, J.; Landais, E.; Le, K.; Reiss, S. M.; Koff, W. C.; Havenar-Daughton, C ..; Heran, M.; Sangha, B.; Walt, D.; Krajden, M.; Crotty, S.; Sok, D.; Briney, B.; Burton, D. R.; Duffy, D.; Foster, L. J.; Mohn, W. W.; Kobor, M. S.; Tebbutt, S. J.; Brinkman, R. R.; Scheuermann, R. H.; Hancock, R.; Kollmann, T. R.; Sadarangani, M. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. Front Immunol 2020, 11, 580373.

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  • Jardine, Joseph G.; Ota, T.; Sok, Devin; Pauthner, Matthias G.; Kulp, D. W.; Kalyuzhniy, O.; Skog, P. D.; Thinnes, T. C.; Bhullar, D.; Briney, Bryan S.; Menis, S.; Jones, M.; Kubitz, M.; Spencer, S.; Adachi, Y.; Burton, Dennis R.; Schief, William R.; Nemazee, David Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science 2015, 349, 156-161.

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  • Zhao, F.; Joyce, C.; Burns, A.; Nogal, B.; Cottrell, C. A.; Ramos, A.; Biddle, T.; Pauthner, M.; Nedellec, R.; Qureshi, H.; Mason, R.; Landais, E.; Briney, B.; Ward, A. B.; Burton, D. R.; Sok, D. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques. Cell Rep 2020, 32, 108122.

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  • Burton, Dennis R.; Briney, Bryan; Andrabi, Raiees; Teijaro, John R.; Voss, James E.; Wilson, Ian A.; Nemazee, David; Smith, Davey M.; Zhao, Fangzhu; Yuan, Meng; Yang, Linlin; Wu, Nicholas C.; Woehl, Jordan L.; Song, Ge; Sok, Devin; Smith, Davey M.; Smith, Chloe; Rogers, Thomas F.; Ricketts, James; Ricciardi, Michael J.; Rawlings, Stephen A.; Ramirez, Sydney I.; Peng, Linghang; Parren, Mara; Limbo, Oliver; Landais, Elise; Jardine, Joseph G.; Hurtado, Jonathan; Huang, Deli; He, Wan-ting; Garcia, Elijah; Callaghan, Sean; Burns, Alison; Beutler, Nathan; Abbott, Robert K. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.. Science (New York, N.Y.) 2020, 956-963.

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  • Joyce, C.; Burton, D. R.; Briney, B. Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing. Sci Rep 2020, 10, 1120.

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  • Briney, Bryan S.; Inderbitzin, A.; Joyce, Collin M.; Burton, Dennis R. Commonality despite exceptional diversity in the baseline human antibody repertoire. Nature 2019, 566, 393-397.

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  • Rogers, Thomas F.; Zhao, Fangzhu; Huang, Deli; Beutler, Nathan; Burns, Alison; He, Wan-ting; Limbo, Oliver; Smith, Chloe; Song, Ge; Woehl, Jordan L.; Yang, Linlin; Abbott, Robert K.; Callaghan, Sean; Garcia, Elijah; Hurtado, Jonathan; Parren, Mara; Peng, Linghang; Ramirez, Sydney I.; Ricketts, James; Ricciardi, Michael J.; Rawlings, Stephen A.; Wu, Nicholas C.; Yuan, Meng; Smith, Davey M.; Nemazee, David; Teijaro, John R.; Voss, James E.; Wilson, Ian A.; Andrabi, Raiees; Briney, Bryan; Landais, Elise; Sok, Devin; Jardine, Joseph G.; Burton, Dennis R. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.. Science 2020, 369, 956-963.

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  • Steichen, J. M.; Lin, Y. C.; Havenar-Daughton, C ..; Pecetta, S.; Ozorowski, G.; Willis, J. R.; Toy, L.; Sok, D.; Liguori, A.; Kratochvil, S.; Torres, J. L.; Kalyuzhniy, O.; Melzi, E.; Kulp, D. W.; Raemisch, S.; Hu, X.; Bernard, S. M.; Georgeson, E.; Phelps, N.; Adachi, Y.; Kubitz, M.; Landais, E.; Umotoy, J.; Robinson, A.; Briney, B.; Wilson, I. A.; Burton, D. R.; Ward, A. B.; Crotty, S.; Batista, F. D.; Schief, W. R. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science 2019, 366.

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  • Havenar-Daughton, C ..; Carnathan, D. G.; Boopathy, A. V.; Upadhyay, A. A.; Murrell, B.; Reiss, S. M.; Enemuo, C. A.; Gebru, E. H.; Choe, Y.; Dhadvai, P.; Viviano, F.; Kaushik, K.; Bhiman, J. N.; Briney, B.; Burton, D. R.; Bosinger, S. E.; Schief, W. R.; Irvine, D. J.; Silvestri, G.; Crotty, S. Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization. Cell Rep 2019, 29, 1756-1766.e8.

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