
Bryan Briney, PhD
Scripps Research Joint Appointments
Education
Ph.D. (Microbiology and Immunology), Vanderbilt University, 2012B.S. (Biochemistry and Cell Biology), University of California, San Diego, 2007
Professional Experience
2017-2018 Assistant Professor of Immunology and Microbiology, Immunology and Microbiology, Scripps Research2015-2017 Assistant Professor of IMS, Immunology and Microbial Science (IMS), Scripps Research
2012-2015 Postdoctoral Fellow, Scripps Research
Selected References
Joyce, C., Burton, D. R. & Briney, B. Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing. (2020). Scientific Reports, 10. PMCID: PMC6981180.
Rogers, T. F., Zhao, F., Huang, D. L., Beutler, N., Burns, A., He, W. T., Limbo, O., Smith, C., Song, G., Woehl, J., Yang, L. L., Abbott, R. K., et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. (2020). Science, 369(6506), 956-963. PMCID: PMC7299280.
Zhao, F., Joyce, C., Burns, A., Nogal, B., Cottrell, C. A., Ramos, A., Biddle, T., Pauthner, M., Nedellec, R., Qureshi, H., Mason, R., Landais, E., et al. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques. (2020). Cell Reports, 32. PMCID: PMC7487785.
Ben-Othman, R., Cai, B., Liu, A. R. C., Varankovich, N., He, D. I., Blimkie, T. M., Lee, A. H., Gill, E. E., Novotny, M., Aevermann, B., Drissler, S., Shannon, C. P., et al. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. (2020). Frontiers in Immunology, 11. PMCID: PMC7672042.
Steichen, J. M., Lin, Y. C., Havenar-Daughton, C., Pecetta, S., Ozorowski, G., Willis, J. R., Toy, L., Sok, D., Liguori, A., Kratochvil, S., Torres, J. L., Kalyuzhniy, O., et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. (2019). Science, 366.
Havenar-Daughton, C., Carnathan, D. G., Boopathy, A. V., Upadhyay, A. A., Murrell, B., Reiss, S. M., Enemuo, C. A., Gebru, E. H., Choe, Y., Dhadvai, P., Viviano, F., Kaushik, K., et al. Rapid germinal center and antibody responses in non-human primates after a single nanoparticle vaccine immunization. (2019). Cell Reports, 29(7), 1756-+.
Blasco, A., Endres, M. G., Sergeev, R. A., Jonchhe, A., Macaluso, N. J. M., Narayan, R., Natoli, T., Paik, J. H., Briney, B., Wu, C., Su, A. I., Subramanian, A., et al. Advancing computational biology and bioinformatics research through open innovation competitions. (2019). PLoS One, 14. PMCID: PMC6764653.
Umotoy, J., Bagaya, B. S., Joyce, C., Schiffner, T., Menis, S., Saye-Francisco, K. L., Biddle, T., Mohan, S., Vollbrecht, T., Kalyuzhniy, O., Madzorera, S., Kitchin, D., et al. Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan. (2019). Immunity, 51(1), 141-154. PMCID: PMC6642152.
Briney, B., Inderbitzin, A., Joyce, C. & Burton, D. R. Commonality despite exceptional diversity in the baseline human antibody repertoire. (2019). Nature, 566(7744), 393-397.
Voss, J. E., Gonzalez-Martin, A., Andrabi, R., Fuller, R. P., Murrell, B., McCoy, L. E., Porter, K., Huang, D., Li, W., Sok, D., Le, K., Briney, B., et al. Reprogramming the antigen specificity of B cells using genome-editing technologies. (2019). Elife, 8. PMCID: PMC6355199.