Bryan Briney, PhD

Assistant Professor
Department of Immunology and Microbiology
California Campus


Scripps Research Joint Appointments

Faculty, Graduate Program


Ph.D. (Microbiology and Immunology), Vanderbilt University, 2012
B.S. (Biochemistry and Cell Biology), University of California, San Diego, 2007

Professional Experience

2017-2018 Assistant Professor of Immunology and Microbiology, Immunology and Microbiology, Scripps Research
2015-2017 Assistant Professor of IMS, Immunology and Microbial Science (IMS), Scripps Research
2012-2015 Postdoctoral Fellow, Scripps Research

Selected References

All Publications

Joyce, C., Burton, D. R. & Briney, B. Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing. (2020). Scientific Reports, 10. PMCID: PMC6981180.

Rogers, T. F., Zhao, F., Huang, D. L., Beutler, N., Burns, A., He, W. T., Limbo, O., Smith, C., Song, G., Woehl, J., Yang, L. L., Abbott, R. K., et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. (2020). Science, 369(6506), 956-963. PMCID: PMC7299280.

Zhao, F., Joyce, C., Burns, A., Nogal, B., Cottrell, C. A., Ramos, A., Biddle, T., Pauthner, M., Nedellec, R., Qureshi, H., Mason, R., Landais, E., et al. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques. (2020). Cell Reports, 32. PMCID: PMC7487785.

Ben-Othman, R., Cai, B., Liu, A. R. C., Varankovich, N., He, D. I., Blimkie, T. M., Lee, A. H., Gill, E. E., Novotny, M., Aevermann, B., Drissler, S., Shannon, C. P., et al. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. (2020). Frontiers in Immunology, 11. PMCID: PMC7672042.

Steichen, J. M., Lin, Y. C., Havenar-Daughton, C., Pecetta, S., Ozorowski, G., Willis, J. R., Toy, L., Sok, D., Liguori, A., Kratochvil, S., Torres, J. L., Kalyuzhniy, O., et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. (2019). Science, 366.

Havenar-Daughton, C., Carnathan, D. G., Boopathy, A. V., Upadhyay, A. A., Murrell, B., Reiss, S. M., Enemuo, C. A., Gebru, E. H., Choe, Y., Dhadvai, P., Viviano, F., Kaushik, K., et al. Rapid germinal center and antibody responses in non-human primates after a single nanoparticle vaccine immunization. (2019). Cell Reports, 29(7), 1756-+.

Blasco, A., Endres, M. G., Sergeev, R. A., Jonchhe, A., Macaluso, N. J. M., Narayan, R., Natoli, T., Paik, J. H., Briney, B., Wu, C., Su, A. I., Subramanian, A., et al. Advancing computational biology and bioinformatics research through open innovation competitions. (2019). PLoS One, 14. PMCID: PMC6764653.

Umotoy, J., Bagaya, B. S., Joyce, C., Schiffner, T., Menis, S., Saye-Francisco, K. L., Biddle, T., Mohan, S., Vollbrecht, T., Kalyuzhniy, O., Madzorera, S., Kitchin, D., et al. Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan. (2019). Immunity, 51(1), 141-154. PMCID: PMC6642152.

Briney, B., Inderbitzin, A., Joyce, C. & Burton, D. R. Commonality despite exceptional diversity in the baseline human antibody repertoire. (2019). Nature, 566(7744), 393-397.

Voss, J. E., Gonzalez-Martin, A., Andrabi, R., Fuller, R. P., Murrell, B., McCoy, L. E., Porter, K., Huang, D., Li, W., Sok, D., Le, K., Briney, B., et al. Reprogramming the antigen specificity of B cells using genome-editing technologies. (2019). Elife, 8. PMCID: PMC6355199.