Scientific Report 2007
sequencing of the human genome promises to propel humans into the age of molecular
medicine, where complex diseases are diagnosed and treated in a patient- and target-specific
manner. For the nervous system, in particular, the postgenome era holds the potential
to deliver groundbreaking new medicines for previously intractable psychiatric disorders
including anxiety, depression, and schizophrenia.
order to realize this goal, a new breed of research institute is needed that cultivates
cross talk among many experimental disciplines. Indeed, unraveling the complexities
of the human brain and behavior can only be achieved by bringing together scientists
from diverse backgrounds and expertise, including chemistry, physics, genetics,
The Helen L.
Dorris Child and Adolescent Neuro-Psychiatric Disorder Institute was established
with a generous gift from mental health advocate and San Diego State University
professor emeritus Helen L. Dorris. Her interest in mental health advocacy led her
to provide the funding to establish this institute, which has a strong emphasis
on interdisciplinary approaches to studies of neurologic and psychiatric disorders.
the aim of scientists at the institute is to uncover the pathologic basis of mental
disorders and to develop therapies for these disorders. Several talented investigators
have been recruited to join the institute. Together, these investigators are addressing
many of the most challenging problems facing contemporary molecular and behavioral
neuroscience. Their research promises to uncover fundamental mechanisms for brain
function and to reveal novel strategies and targets for the treatment of nervous