Low, L.Y., Yang, C., Perego, M., Osterman, A., Liddington, R. 2011. The role of net charge on the catalytic domain and the influence of the cell-wall binding domain on the bactericidal activity, specificity and host-range of phase lysins. J Biol. Chem. Aug 4 [Epub ahead of print]. ABSTRACT
Baker, K.A., Perego, M. 2011. Transcription antitermination by a phosphorylated response regulator and cobalamin-dependent termination at a B12 riboswitch contribute to ethanolamine utilization in Enterococcus faecalis. J. Bacteriol.  May; 193(10):2575-86. [Epub 2011 Mar 25]. ABSTRACT
Steiner, E., Dago, A.E., Young, D.I., Heap, J.T., Minton, N.P., Hoch, J.A., Young, M.  2011.  Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in Clostridium acetobutylicum. May; 80(3):641-54. doi: 10.1111/j.1365-2958.2011.07608.x. [Epub 2011 Mar 14]. ABSTRACT
Procaccini, A., Lunt, B., Szurmant, H., Hwa, T., Weigt, M. 2011. Dissecting the specificity of protein-protein interaction in bacterial two-component signaling: orphans and corsstalks. PLoS One. 2011 May. 9;6(5):e19729 [Epub - in process] ABSTRACT
Del Papa, MF., Perego, M. 2011. Enterococcus faecalis virulence regulator FsrA binding to target promoters. J. Bacteriol.  Apr; 193(7):1527-32. [Epub 2011 Jan 21]. ABSTRACT
Stranzl G.R., Santelli E., Bankston L.A., La Clair C., Bobkov A., Schwarzenbacher R., Godzik A., Perego M. Grynberg M., Liddington R.C. 2011. Structural insights into inhibition of Bacillus anthracis sporulation by a novel class of non-heme globin sensor domains. J. Biol. Chem. Jan 07; [Epub ahead of print]. ABSTRACT
Chiang C., Bongiorni C., Perego M. 2011. Glucose-dependent activation of Bacillus anthracis toxin gene expression and virulence requires the carbon catabolite protein CcpA. J. Bacteriol.  Jan; 193(1):52-62.[Epub 2010 Oct 22]. ABSTRACT
Fukushima T., Furihata I., Emmins R., Daniel R.A., Hoch J.A., Szurmant H.  2011.  A role for the essential YycG sensor histidine kinase in sensing cell division. Mol. Microbiol. Jan; 79(2):503-22.[Epub 2010 Nov 29]. ABSTRACT
Bobay, B.G., Thompson, R.J., Hoch, J.A. and Cavanagh, J. 2010. Long range dynamic effects of point-mutations trap a response regulator in an active conformation. FEBS Lett.  Oct 8; 584(19):4203-7. [Epub 2010 Sep 7]. ABSTRACT
Hobbs C.A., Bobay B.G., Thompson R.J., Perego M., Cavanagh J. 2010. NMR solution structure and DNA-binding model of the DNA-binding domain of competence protein A. J.Mol.Biol.  Apr 30; 398(2):248-63. [Epub 2010 Mar 17].ABSTRACT
Szurmant H., Hoch J.A. 2010. Interaction fidelity in two-component signaling. Curr. Opin. Microbiol. Apr; 13(2):190-7. [Epub 2010 Feb 3]. Review. ABSTRACT
Schug A., Weigt M., Hoch, J.A., Onuchic J.N., Hwa T., Szurmant H. 2010. Computational modeling of phosphotransfer complexes in two-component signaling. Methods Enzymol. 471:43-58. [Epub 2010 Mar 1]. ABSTRACT
Lunt B., Szurmant H., Procaccini A., Hoch, J.A., Hwa T., Weigt M. 2010. Inference of direct residue contacts in two-component signaling. Methods Enzymol. 471:17-41. [Epub 2010 Mar 1]. ABSTRACT
Chang, C., Tesar C., Gu M., Babnigg G., Joachimiak A., Pokkuluri P.R., Szurmant H., Schiffer M. 2010. Extracytoplasmic PAS-like domains are common in signal transduction proteins. J Bacteriol. Feb; 192(4):1156-9. [Epub 2009 Dec 11]. ABSTRACT
Shug A., Weigt, M., Onuchic J.N., Hwa T., Szurmant, H.  2009.  High-resolution protein complexes from integrating genomic information with molecular simulation. Proc. Natl. Acad. Sci. USA. Dec 29; 106(52):22124-9. [Epub 2009 Dec 17]. ABSTRACT
Zhao H, Volkov A, Veldore VH, Hoch JA, Varughese KI. 2009. Crystal structure of the transcriptional repressor PagR of Bacillus anthracis. Microbiology. Nov 19. [Epub ahead of print] ABSTRACT
Lehmann, M., Noack, D., Wood, M., Perego, M., Knaus, U. 2009. Lung epithelial injugy by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrity. PLoS One. March. 4(3):e4755 [Epub ahead of print] ABSTRACT
Wilson, A.C., Hoch, J.A., Perego, M.  2009.  Two small c-type cytochromes affect virulence gene expression in Bacillus anthracis. Mol. Microbiol. 72(1):109-23. ABSTRACT
Weigt, M., White, R.A., Szurmant, H., Hoch, J.A., Hwa, T.  2009.  Identification of direct residue contacts in protein-protein interaction by message passing. Proc. Natl. Acad. Sci. USA. 106(1):67-72. ABSTRACT
Scaramozzino, F., White, A., Perego, M., Hoch, J.A.  2009.  A unique GTP-dependent sporulation sensor histidine kinase in Bacillus anthracis. J Bacteriol.  191(3):687-92. ABSTRACT
Wilson, A.C., Soyer, M., Hoch, J.A., Perego, M.  2008. The bicarbonate transporter is essential for Bacillus anthracis lethality. PLoS Pathog.  4(11):e1000210. ABSTRACT
Del Papa, M.F. and Perego, M. 2008. Ethanolamine activates a sensor histidine kinase regulating its utilization in Enterococcus faecalis. J. Bacteriol.  190(21):7147-56. ABSTRACT
Bongiorni, C., Fukushima, T., Wilson, A.C., Chiang, C., Mansilla, M.C., Hoch, J.A. and Perego, M. 2008. Dual promoters control the expression of the Bacillus anthracis virulence factor AtxA. J Bacteriol. Oct;190(19):6483-92. ABSTRACT
Fukushima, T., Szurmant, H., Kim, E.-J., Perego, M. and Hoch, J.A. 2008. A sensor histidine kinase coordinates cell wall architecture with cell division in Bacillus subtilis. Mol. Microbiol. 69(3):621-32. ABSTRACT
Szurmant, H., Bobay, B.G., White, R.A., Sullivan, D.M., Thompson, R.J., Hwa, T., Hoch, J.A. and Cavanagh, J. 2008. Co-evolving motions at protein-protein interfaces of two-component signaling systems identified by covariance analysis. Biochemistry. 47(30):7782-4. ABSTRACT
Wilson, A.C., Hoch, J.A. and Perego, M. 2008. Virulence gene expression is independent of ResDE-regulated respiration control in Bacillus anthracis. J. Bacteriol. 190(15):5522-5. ABSTRACT
Perego, M. and Hoch, J.A. 2008. Commingling regulatory systems following acquisition of virulence plasmids by Bacillus anthracis. Trends Microbiol. 16(5):215-21. ABSTRACT
Szurmant, H., Bu, L., Brooks III, C.L. and Hoch, J.A. 2008. An essential sensor histidine kinase controlled by transmembrane helix interactions with its auxiliary proteins. Proc Natl Acad Sci . 105(15):5891-6. ABSTRACT
Winkler, M.E. and Hoch, J.A. 2008. Essentiality, bypass, and targeting of the YycFG (VicRK) two-component regulatory system in Gram-positive bacteria. J. Bacteriol.190(8):2645-8. ABSTRACT

Szurmant, H., White, R.A. and Hoch, J.A. 2007. Sensor complexes regulating two-component signal transduction. Curr. Opin. Struct. Biol. 17(6):706-15. ABSTRACT

Diaz, A.R., Stephenson, S., Green, J.M., Levdikov, V.M., Wilkinson, A.J. and Perego, M. 2007. Functional role for a conserved aspartate in the Spo0E signature motif involved in the dephosphorylation of the Bacillus subtilis sporulation regulator Spo0A. J Biol. Chem. 283(5):2962-72. ABSTRACT
Del Papa, M.F., Hancock, L., Thomas, V. and Perego, M. 2007. Full activation of Enterococcus faecalis gelatinase by a C-terminal proteolytic cleavage. J. Bacteriol.189(24):8835-43. ABSTRACT
Wilson, A.C., Perego, M. and Hoch, J.A. 2007. New transposon delivery plasmids for insertional mutagenesis in Bacillus anthracis. J. Microbiol. Methods.71(3):332-5. ABSTRACT
Szurmant, H., Fukushima, T. and Hoch, J.A. 2007. The Essential YycFG Two-Component System of Bacillus subtilis. Methods Enzymol. 422:396-417. ABSTRACT
White, R.A., Szurmant, H., Hoch, J.A. and Hwa, T. 2007. Features of protein-protein interactions in two-component signaling deduced from genomic libraries. Methods Enzymol. 422:75-101. ABSTRACT
McLaughlin, P.D., Bobay, B.G., Regel, E.J., Thompson, R.J., Hoch, J.A. and Cavanagh, J. 2007. Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition. FEBS Lett. 581(7):1425-9. ABSTRACT
Szurmant, H., Mohan, M.A., Imus, P.M. and Hoch, J.A. 2007. YycH and YycI interact to regulate the essential YycFG two-component system in Bacillus subtilis. J. Bacteriol. 189(8):3280-9. ABSTRACT
Santelli, E., Liddington, R.C, Mohan, M.A., Hoch, J.A. and Szurmant, H. 2007. The crystal structure of Bacillus subtilis YycI reveals a common fold for two members of an unusual class of sensor histidine kinase regulatory proteins. J. Bacteriol. 189(8):3290-5. ABSTRACT
Smits, W.K., Bongiorni, C., Veening, J.W., Hamoen, L.W., Kuipers, O.P. and Perego, M. 2007. Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis. Mol. Microbiol. 65(1):103-20. ABSTRACT
Bongiorni, C., Stoessel, R. and Perego, M. 2007. Negative regulation of Bacillus anthracis sporulation by the Spo0E family of phosphatases. J. Bacteriol. 189(7):2637-45. ABSTRACT
Tsvetanova, B., Wilson, A.C., Bongiorni, C., Chiang, C., Hoch, J.A. and Perego, M. 2007. Opposing effects of histidine phosphorylation regulate the AtxA virulence transcription factor in Bacillus anthracis. Mol. Microbio. 63(3):644-55. ABSTRACT
Grenha, R., Rzechorzek, N.J., Brannigan, J.A., de Jong, R.N., Ab, E., Diercks, T., Truffault, V., Ladds, J.C., Fogg, M.J., Bongiorni, C., Perego, M., Kaptein, R., Wilson, K.S., Folkers, G.E. and Wilkinson, A.J. 2006. Structural characterization of Spo0E-like protein aspartic acid phosphatases that regulate sporulation in Bacilli. J. Biol. Chem. 218(49):37993-8003. ABSTRACT
White, A.K., Hoch, J.A., Grynberg, A., Godzik, A. and Perego, M. 2006. Sensor domains encoded in Bacillus anthracis virulence plasmids prevent sporulation by hijacking a sporulation sensor histidine kinase. J. Bacteriol. 188(17):6354-60. ABSTRACT
Szurmant, H., Zhao, H., Mohan, M.A., Hoch, J.A. and Varughese K.I. 2006. The Crystal structure of YycH involved in the regulation of the essential YycFG two-component system in ,em>Bacillus subtilis,/em> reveals a novel tertiary structure. Protein Science 15(4):929-934. ABSTRACT
Worner, K., Szurmant, H., Chiang, C. and Hoch, J.A. 2006. Phosphorylation and Functional Analysis of the Sporulation Initiation Factor Spo0A from Clostridium botulinum. Mol. Microbiol. 59(3):1000-1012. ABSTRACT
Bongiorni, C., Stoessel, R., Shoemaker, D. and Perego M. 2006. Rap phosphatase of virulence plasmid pXO1 inhibits Bacillus anthracis sporulation. J. Bacteriol. 188(2):487-498. ABSTRACT
Kojetin, D.J., Thompson, R.J., Benson, L.M., Naylor, S., Waterman, J., Davies, K.G., Opperman, C.H., Stephenson, K., Hoch, J.A. and Cavanagh, J. 2005. Structural analysis of divalent binding to the Bacillus subtilis response regulator Spo0F: the possibility for in vitro metalloregulation in the initiation of sporulation. Biometals. 18(5):449-466. ABSTRACT
Brunsing, R.L., La Clair, C., Chiang, C., Hancock, L.E., Perego, M. and Hoch, J.A. 2005. Characterization of sporulation histidine kinases of Bacillus anthracis. J. Bacteriol. 187(20):6972-81. ABSTRACT
Low, L.Y., Yang, C., Perego, M., Osterman, A. and Liddington, R.C. 2005. Structure and lytic activity of a bacillus anthracis prophage endolysin. J Biol Chem. 280(42):35433-9. ABSTRACT
Szurmant, H., Nelson, K., Kim, E.J., Perego, M. and Hoch, J.A. 2005. YycH regulates the activity of the essential YycFG two-component system in Bacillus subtilis. J Bacteriol.187(15):5419-26. ABSTRACT
Musumeci, L., Bongiorni, C., Tautz, L., Edwards, R.A., Osterman, A., Perego, M., Mustelin, T. and Bottini, N. 2005. Low-molecular-weight protein tyrosine phosphatases of Bacillus subtilis. J Bacteriol. 187(14):4945-56. ABSTRACT
Bongiorni, C., Ishikawa, S., Stephenson, S., Ogasawara, N. and Perego, M. 2005. Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems. J Bacteriol. 187(13):4353-61. ABSTRACT
Hancock, L.E. and M. Perego. 2004. Systematic Inactivation and Phenotypic Characterization of Two-Component Signal Transduction Systems of Enterococcus faecalis V583. J. Bacteriol. 186(23):7951-7958. ABSTRACT
Hancock, L.E. and M. Perego. 2004. The Enterococcus faecalis fsr Two-Component System Controls Biofilm Development through Production of Gelatinase. J. Bacteriol. 186(17):5629-39. ABSTRACT
Kao, M.C, Di Bernardo, S., Perego, M., Nakamaru-Ogiso, E., Matsuno-Yagi, A. and Yagi, T. 2004. Functional roles of four conserved charged residues in the membrane domain subunit NuoA of the proton-translocating NADH-quinone oxidoreductase from Escherichia coli. J Biol Chem. 279(31):32360-6. ABSTRACT
Stephenson, K. and J.A. Hoch. 2004. Developing Inhibitors to Selectively Target Two-Component and Phosphorelay Signal Transduction Systems of Pathogenic Microorganisms. Curr. Med. Chem. 11(6):765-73. ABSTRACT
M. Perego, J.A. Hoch and Barrett, J.F. 2004. Functional Genomics of Gram-Positive Microorganisms. J. Bacteriol. 186(4):903-909. ABSTRACT
Core, L. and M. Perego. 2003. TPR-mediated interaction of RapC with ComA inhibits response regulator-DNA binding for competence development in Bacillus subtilis. Mol. Microbiol. 49(6):1509-1522. ABSTRACT
Stephenson, S., Mueller, C., Jiang, M. and M. Perego. 2003. Molecular analysis of Phr peptide processing in Bacillus subtilis. J. Bacteriol. 185(16):4861-1871.  ABSTRACT

Stephenson, K. and J.A. Hoch. 2002. Histidine kinase-mediated signal transduction systems of pathogenic microorganisms as targets for therapeutic intervention. Curr. Drug Targets – Infectious Disorders. 2(3):235-24. ABSTRACT

Stephenson, K. and J.A. Hoch. 2002. Evolution of signaling in the sporulation phosphorelay. Mol. Microbiol. 46(2):297-304. ABSTRACT
Hancock, L. and M. Perego. 2002. Two-component signal transduction in Enterococcus faecalis. J. Bacteriol. 184(21):5819-5825.  ABSTRACT
Stephenson, K. and J.A. Hoch. 2002. Two-component and phosphorelay signal transduction systems as therapeutic targets. Curr.Opin.Pharm. 2(5):507-512.  ABSTRACT
Zhao, H., T. Msadek, J. Zapf, Madhusudan, J.A. Hoch and K.I. Varughese. 2002. DNA complexed structure of the key transcription factor initiating development in sporulating bacteria. Structure 10(8):1041-1050. ABSTRACT
Stephenson, K. and Hoch, J. A. 2002. Virulence- and antibiotic resistance-associated two-component signal transduction systems of Gram-positive pathogenic bacteria as targets for anti-microbial therapy. Pharmacology and Therapeutics 93(2-3):293-305. ABSTRACT
Stephenson, S.J. and M. Perego. 2002. Interaction surface of the Spo0A response regulator with the Spo0E phosphatase. Mol. Microbiol. 44(6):1455-1467.  ABSTRACT
Ishikawa, S., Core, L.J. and M. Perego. 2002. Biochemical characterization of aspartyl phosphate phosphatase interaction with a phosphorylated response regulator and its inhibition by a pentapeptide. J. Biol. Chem. 277(23):20483-20489.  ABSTRACT
Sievers, J., B. Raether, M. Perego and J. Errington. 2002. Characterization of the parB-like yyaA gene of Bacillus subtilis. J. Bacteriol. 184(4):1102-1111.  ABSTRACT
Kanamaru, K., S. Stephenson and M. Perego. 2002. Overexpression of the PepF oligopeptidase inhibits sporulation initiation in Bacillus subtilis. J. Bacteriol. 184(1):43-50.  ABSTRACT
Perego, M. and J.A. Hoch. 2002. Two-component systems, phosphorelays and regulation of their activities by phosphatases, pp.473-481. In A.L. Sonenshein, et. al. (ed.) Bacillus subtilis and Its Closest Relatives: From Genes to Cells. ASM Press, Washington, D.C. ABSTRACT
Stephenson, K. and J.A. Hoch. 2001. PAS-A domain of phosphorelay sensor kinase A: A catalytic ATP-binding domain involved in the initiation of development in Bacillus subtilis. PNAS 98(26):15251-15256. ABSTRACT
Perego, M. and J.A. Hoch. 2001. Functional genomics of Gram-positive microorganisms: Review of the meeting, San Diego, California, 24 to 28 June 2001. J. Bacteriol. 183(24):6973-6978. ABSTRACT 
Sen, U., Vasudevan, S., Subbarao, G., McClintock, R.A., Celikel, R., Ruggeri, Z.M. and K.I. Varughese. 2001. Crystal structure of the von Willebrand factor modulator botrocetin. Biochemistry 40(2):345-352.
Perego, M. 2001. A new family of aspartyl phosphate phosphatases targeting the sporulation transcription factor Spo0A of Bacillus subtilis. Mol. Microbiol. 42(1):133-143. ABSTRACT
Perego, M. and J.A. Brannigan. 2001. Pentapeptide regulation of aspartyl-phosphate phosphatases. Peptides 22(10):1541-1547. ABSTRACT 
Core, L.J., Ishikawa, S., and M. Perego. 2001. A free terminal carboxylate group is required for PhrA pentapeptide inhibition of RapA phosphatase. Peptides 22(10):1549-1553. ABSTRACT
Varughese, K.I. and J.A. Hoch. 2001. Keeping signals straight in phosphorelay signal transduction. J. Bacteriol. 183(17):4941-4949. ABSTRACT
Wang, M., Fabret, C., Kanamaru, K., Stephenson, K., Dartois, V., Perego, M., and J.A. Hoch. 2001. Dissection of the functional and structural domains of phosphorelay histidine kinase A of Bacillus subtilis. J. Bacteriol. 183(9):2795-2802. ABSTRACT
Celikel, R., Ruggeri, Z.M. and K.I. Varughese. 2000. von Willebrand factor conformation and adhesive function is modulated by an internalized water molecule. Nature Structural Biol. 7(10):881-884.  ABSTRACT
Zapf, J., Sen, U., Madhusudan, Hoch, J.A., and K.I. Varughese. 2000. A transient interaction between two phosphorelay proteins trapped in a crystal lattice reveals the mechanism of molecular recognition and phosphotransfer in signal transduction. Structure 8(8):851-862.  ABSTRACT
Jiang, M., Shao, W., Perego, M., and J.A. Hoch. 2000. Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis. Mol. Microbiol. 38(3):535-542.  ABSTRACT
Stephenson, K., Yamaguchi, Y., and J.A. Hoch. 2000. The Mechanism of Action of Inhibitors of Bacterial Two-component Signal Transduction Systems. J. Biol. Chem. 275(49):38900-38904. ABSTRACT
Jiang, M., Grau, R., and M. Perego. 2000. Differential processing of propeptide Inhibitors of Rap Phosphatases in Bacillus subtilis. J. Bacteriol. 182(2):303-310. ABSTRACT
J.A. Hoch. 2000. Two-component and Phosphorelay Signal Transduction. Curr. Opin. Microbiol. 3(2):165-170. ABSTRACT
Strauch, M.A. and J.A. Hoch. 1999. Spores, Sporulation, pp.2417-2421. In T.E. Creighton (ed.) The Encyclopedia of Molecular Biology. John Wiley & Sons, New York, NY. ABSTRACT
Gilmore, M.S. and J.A. Hoch. 1999. Antibiotic Resistance: A Vancomycin surprise. Nature 399(6736):524-527. ABSTRACT
Koide, A., M. Perego and J.A. Hoch. 1999. ScoC Regulates Peptide Transport and Sporulation Initiation in Bacillus subtilis. J. Bacteriol. 181(13):4114-4117.  ABSTRACT
Jiang, M., Y.-L. Tzeng, V.A. Feher, M. Perego and J.A. Hoch. 1999. Alanine Mutants of the Spo0F Response Regulator Modifying Specificity for Sensor Kinases in Sporulation Initiation. Mol. Microbiol. 33(2):389-395. ABSTRACT
Fabret, C., V.A. Feher and J.A. Hoch. 1999. Two-Component Signal Transduction In Bacillus subtilis: How One Organism Sees Its World. J. Bacteriol. 181(7):1975-1983.  ABSTRACT
Perego, M. 1999. Self-signaling by Phr peptides modulate Bacillus subtilis development, pp. 243-258. In Cell-Cell signaling in Bacteria. G.M. Dunny, and S.C. Winans (Eds.) ASM Press, Washington, D.C. ABSTRACT
Fabret, C. and J.A. Hoch. 1998. A Two-Component Signal Transduction System Essential for Growth of Bacillus subtilis: Implications for Anti-Infective Therapy. J. Bacteriol. 180(23):6375-6383. ABSTRACT
Varughese, K.I., Madusudan, X.Z. Zhou, J.M. Whiteley and J.A. Hoch. 1998. Formation of a Novel Four-Helix Bundle and Molecular Recognition Sites by Dimerization of a Response Regulator Phosphotransferase. Molec. Cell. 2(4):485-493 
Tzeng, Y.-L., V.A. Feher, J. Cavanagh, M. Perego and J.A. Hoch. 1998. Characterization of interactions between a two-component response regulator, Spo0F, and its phosphatase, RapB. Biochemistry 37(47):16538-16545
Tzeng, Y.-L., X.Z. Zhou and J.A. Hoch. 1998. Phosphorylation of the Spo0B response regulator phosphotransferase initiating development in Bacillus subtilis. J. Biol. Chem. 273(37):23849-23855 
Cervin, M.A., G.B. Spiegelman, B. Raether, K. Ohlsen, M. Perego and J.A. Hoch. 1998. A negative regulator linking chromosome segregation to developmental transcription in Bacillus subtilis. Mol. Microbiol. 29(1):85-95
Barrett, J.F. and J.A. Hoch. 1998. Two-component signal transduction as a target for microbial anti-infective therapy. Antimicrob. Agents. Chemother. 42(7):1529-1536
Hoch, J.A. 1998. Initiation of bacterial development. Current Opinion Microbiol. 1(2):170-174
Feher,V.A., Y-L. Tzeng, J.A. Hoch and John Cavanagh. 1998. Identification of communication networks in Spo0F: a model for phosphorylation-induced conformational change and implications for activation of multiple domain bacterial response regulators. FEBS Letters 425:1-6 
Barrett, J.F., R.M. Goldschmidt, L.E. Lawrence, B. Foleno, R. Chen, J.P. Demers, S. Johnson, R. Kanojia, J. Fernandez, J. Bernstein, L. Licata, A. Donetz, S. Huang, D.J. Hlasta, M.J. Macielag, K. Ohemeng, R. Frechette, M.B. Frosco, D.H. Klaubert, J.M. Whiteley, L. Wang and J.A. Hoch. 1998. Novel antibacterial agents that inhibit two-component signal transduction systems. Proc.Natl.Acad.Sci.USA 95(9):5317-5322
Manson, M.D., J.P. Armitage, J.A. Hoch and R.M. MacNab. 1998. Bacterial locomotion and signal transduction. J. Bacteriol. 180(5):1009-1022 
Demina, A., Varughese, K.I., Barbot, J., Forman, K., Beutler, E. 1998. Six previously undescribed pyruvate kinase mutations causing enzyme deficiency. Blood 92(2):647-652
Zapf, J., Madusudan, C.E. Grimshaw, J.A. Hoch, K.I. Varughese and J.M. Whiteley. 1998. A source of response regulator autophosphatase activity: the critical role of a residue adjacent to the Spo0F autophosphorylation active-site. Biochemistry 37(21):7725-7732 
Grimshaw, C.E., C.G. Hanstein, M.A. Strauch, D. Burbulys, S. Huang, L. Wang, J.A. Hoch and J.M. Whiteley. 1998. Synergistic kinetic interactions between components of the phosphorelay controlling sporulation in Bacillus subtilis. Biochemistry 37(5):1365-1375 
Celikel, R., Varughese, K.I., Madhusudan, Yoshioka, A., Ware, J., Ruggeri, Z.M. 1998. Crystal structure of the von Willebrand factor A1 domain in complex with function blocking NMC-4 Fab. Nature Struc. Biol. 5:189-194.
Perego, M. 1998. Kinase-phosphatase competition regulates Bacillus subtilis development. Trends in Microbiol. 6(9):366-370 
Strauch, M.A. and J.A. Hoch. 1997. Spores, Sporulation. In T.E. Creighton (ed.) The Encyclopedia of Molecular Biology. John Wiley & Sons.
Hoch, J.A. and R. Losick. 1997. Panspermia, spores and the Bacillus subtilis genome. Nature. 390(6657):237-238 
Reizer, J., A. Reizer, M. Perego and M.H. Saier, Jr. 1997. Characterization of a family of bacterial response regulator aspartyl-phosphate (RAP) phosphatases. Microb. & Compar. Genom. 2(2):103-111
Celikel, R., Madhusudan, Varughese, K.I., Shima, M., Yoshioka, A., Ware, J., Ruggeri, Z.M. 1997. Crystal structure on NMC-4 Fab anti-von Willebrand Factor A1 domain. Blood Cells, Molecules & Dis. 23(7):123-134 
Dartois,V., T. Djavakhishvili and J.A. Hoch. 1997. KapB is a lipoprotein required for KinB signal transduction and activation of the phosphorelay to sporulation in Bacillus subtilis. Mol.Microbiol. 26(5):1097-1108 
Balakrishnan, R., Ramasubbu, N., Varughese, K.I., Parthasarathy, R. 1997. Crystal structures of the copper and nickel complexes of Rnase A: Metal-induced interprotein interactions and identification of a novel copper binding motif. Proc.Natl.Adac.Sci.USA. 94(18):9620-9625 
Madusudan, J.W. Zapf, J.A. Hoch, J.M. Whiteley, N.H. Xuong and K.I. Varughese. 1997. A response regulatory protein with the site of phosphorylation blocked by an arginine interaction: crystal structure of Spo0F from Bacillus subtilis. Biochemistry. 36(42):12739-12745
Perego, M. 1997. A peptide export-import control circuit modulating bacterial development regulates protein phosphatases of the phosphorelay. Proc. Natl. Acad. Sci. USA. 94(16):8612-8617 
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Tzeng, Y.-L. and J.A. Hoch. 1997. Molecular recognition in signal transduction: the interaction surfaces of the Spo0F response regulator with its cognate phosphorelay proteins revealed by alanine scanning mutagenesis. J.Mol.Biol. 272(2):200-212 
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