Source: Interfolio F180


Sergio Catz

Professor
Department of Molecular and Cellular Biology


 Email

Education

Ph.D., University of Buenos Aires, Argentina, 1997
B.S., University of Buenos Aries, Argentina, 1991

Professional Experience

1998-2002 Postdoctoral Associate, Scripps Research
2002-2004 Research Associate Sr, Scripps Research
2004-2010 Assistant Professor, Scripps Research
2010-2017 Associate Professor, Molecular & Experimental Medicine, Scripps Research
2017-2017 Associate Professor, Molecular Medicine, Scripps Research
2017-Present Professor, Molecular Medicine, Scripps Research

Awards & Professional Activities

2019 NIH, MBPP study section, permanent member, NIH

2016 Editorial Review Board, Cystinosis Research Foundation

2014 Editorial board member, Journal of Biological Chemistry

2011 International Scientific Advisory Board of the biennial symposium “Neutrophil in Immunity" 

2010 Committee member - Molecular and Cellular Biology Affinity Group Seminar Series, The Scripps Research Institute

2000 Postdoctoral fellowship in Neutrophil Function held at The Scripps Research Institute, La Jolla, CA, USA, The American Heart Association

1998 Postdoctoral Fellowship in Neutrophil Function held at The Scripps Research Institute, La Jolla, CA, USA, Ministerio de Education de la Nación, Argentina 

1994 Pre-doctoral Fellowship in Biological Chemistry held at the Department of Biological Chemistry, Faculty of Pharmacy and Biochemistry, The University of Buenos Aires

1992 Pre-doctoral Fellowship in Biochemistry held at The Laboratory of Oxygen Metabolism, School of Medicine, The University of Buenos Aires

1991 Student Fellowship in Biochemistry held at The Department of Clinical Biochemistry, Faculty of Pharmacy and Biochemistry, The University of Buenos Aires

1995 Prize Boeringher Ingelheim for the best work presented in poster at the XIX. Jornadas Anuales de Progresos en Alergia, Asma e Inmunología, Buenos Aires, Argentina


Selected Publications

Perego, M.; Catz, S. D.; Zhu, Y. P.; Zhang, J.; Zgajnar, N. R.; Ramadass, M.; Rahman, F.; Pestonjamasp, K.; Perego, M.; Napolitano, G.; Meneses-salas, E.; Kiosses, W. B.; Johnson, J. L.; Hedrick, C. C.; Gunton, J. E.; Gontijo, R. C.; Catz, S. D. The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy.. Journal of Leukocyte Biology 2021, 110, 629-649.
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allen, d.; askari, k.; billadeau, d. d.; catz, s. d.; chen, d.; gontijo, r. c.; grinstein, s.; hedrick, c. c.; henderson, s. c.; johnson, j. l.; kiosses, w. b.; meneses-salas, e.; monfregola, j.; osborne, d. g.; pestonjamasp, k.; rahman, f.; ramadass, m.; ursini, m. v.; wineinger, n.; yu, j.; zhang, j.; zhu, y. p.

Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation

. Nature Communications 2022.
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Zeng, F.; Yang, M.; Watkins, S. C.; Sullivan, M. L.; Stolz, D. B.; Shufesky, W. J.; Pelanda, R.; Oberbarnscheidt, M. H.; Morelli, A. E.; Larregina, A. T.; Erdos, G.; Chen, Z.; Chen, R.; Catz, S. D.; Camirand, G.; Calderon, M.; Brennan, T. V.; Baty, C. J.; Bandyopadhyay, M. Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation.. Science Translational Medicine 2021, 13, eabb0122.
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Zhang, J.; Rahman, F.; Pestonjamasp, K.; Johnson, J. L.; He, J.; Cherqui, S.; Catz, S. D. DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis.. Autophagy 2021, 18, 1108-1126.
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Karmakar, M.; Minns, M.; Greenberg, E. N.; Diaz-Aponte, J.; Pestonjamasp, K.; Johnson, J. L.; Rathkey, J. K.; Abbott, D. W.; Wang, K.; Shao, F.; Catz, S. D.; Dubyak, G. R.; Pearlman, E. N-GSDMD trafficking to neutrophil organelles facilitates IL-1 beta release independently of plasma membrane pores and pyroptosis. Nature Communications 2020, 11, 2212.
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Catz, S. D.; McLeish, K. R. Therapeutic targeting of neutrophil exocytosis. Journal of Leukocyte Biology 2020, 107, 393-408.
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Rohwedder, I.; Kurz, A. R.; Pruenster, M.; Immler, R.; Pick, R.; Klapproth, S.; Johnson, J. L.; Lowell, C. A.; Mocsai, A.; Catz, S. D.; Sperandio, M.; Alsina, S. M.; Eggersmann, T. K. Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration.. Haematologica 2020, 105, 1845-1856.
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