Senior Faculty News:
Promotions and Appointments
Four senior faculty promotions were announced at a recent
meeting of The Scripps Research Institute (TSRI) Board of
Steven Henriksen, who was promoted to professor
in the Department of Neuropharmacology. Henriksen (B.A.,
University of California, Santa Barbara; Ph.D., Stanford
University School of Medicine), who joined the institute
in 1983, is interested in discerning the functional organization
of neural circuits where intrinsic capacities for both
normal and abnormal behaviors emerge. To understand how
the brain initiates, promotes, and alters behavior, his
research seeks to determine the hierarchical role that
specific central nervous system neuronal circuits and
their chemical messengers have in initiating appropriate
complex responses to external (and internal) sensory events.
Juan Carlos de la Torre, who was promoted to associate
professor with tenure in the Department of Neuropharmacology.
De la Torre (undergraduate degree, Universidad Autonoma
de Madrid, Spain; Ph.D., Centro de Biologia Molecular
Severo Ochoa, Spain) has been at TSRI since 1989. His
research focuses on the molecular and cell biology of
the prototypic arenavirus LCMV and the novel neurotropic
agent Borna disease virus and the mechanisms whereby these
viruses persist within the central nervous system, disrupting
normal brain function.
Nigel Mackman, who was promoted to associate professor
with tenure in the Departments of Immunology and Cell
Biology. Mackman (B.Sc., Ph.D., University of Leicester,
England), joined the institute in 1987 as a research fellow.
His laboratory studies the crosstalk between the coagulation
protease cascade and inflammation using human monocytic
cell lines and human monocytes to elucidate the positive
and negative regulatory intracellular signaling networks
and transcription factors that control the expression
of procoagulant and inflammatory genes. In addition, the
lab generates transgenic models to examine the role of
these proteins in sepsis and ischemia-reperfusion injury.
Luc Teyton, was promoted to associate professor
with tenure in the Department of Immunology. Teyton (M.D.,
Caen Medical School; Ph.D., University of Paris, France)
arrived at TSRI in 1997. His research focuses on the structure
and function of T cell receptor activations, antigen presentatio,
and innate receptor recognition.
In other news about senior faculty, investigator Hugh
Rosen has joined the institute:
Hugh Rosen, professor in the Department of Immunology,
and chair, Committee for Advanced Human Therapeutics.
Rosen (M.D., University of Cape Town; D.Phil., University
of Oxford) studies the regulation of lymphocyte trafficking
and immunosuppression by lysophospholipid receptor agonists.
He uses biological and chemical approaches to suppress
or stimulate the immune response and derive better potential
therapies for transplantation rejection and autoimmune