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I have been here for two years. I finished my Ph.D.
in Israel at Technion, the Israel Institute of Technology.
I wanted to have the experience doing research in one
of the most famous places in the world where the research
is really [conducted] at a high level.
I came with my husband and two kids. We were at a
hotel for seven days while we were trying to find an
apartment. I started to work a few days after that.
My husband came here and his company in Israel organized
a job for him here.
My husband is American, so this job was also an opportunity
to be in America and to know a different place. I wanted
to see if this could be a country for us. And we like
it here, so were planning to stay. I am now looking
for a job. Biotechnology companies, probably.
Before I came here, I was finishing my M.D. in Switzerland,
at the University of Berne. During medical school I
was always working in a lab, doing all these little
things. My mentor back then knew my P.I. I met [Associate
Professor] Dan [Salomon] once at a meeting, and we talked
a little bit. I was always interested in science, especially
in basic science. I think its important for an
M.D. to have knowledge of basic science.
Ive been here for two and a half years. I will
stay here six more months and then do my internship
and residency, then I will go back to academic research.
The last thing I remember about Switzerland is saying
goodbye to my family at the airport and all that stuff.
Hugs and kisses, see you soon, and take care. Father
and mother telling me, "Look out that you eat regularly."
But my wife was coming with me, so it was OK.
I like the weather and the beaches and the people
here. Open minded. I like the mentality here. Everybody
is working hard, but it also has this other side, this
relaxed side. Its really nice.
Before I came here, I did a Ph.D. with David Hart at
Ohio State in synthetic organic chemistry. I wanted
to broaden my scientific background a little bit. Im
really interested in rational drug designchemistry
with a medicinal spinlooking at the functionality
of the molecule with regard to its biological activity
and trying to understand the relationship between the
two. [In other words], how its biological activity is
derived through its functionality. Dr. Boger does that
in his lab. Im studying an analogue of an anti-tumor
Ive been here a little over a year. I packed
everything into a U-Haul and drove out here dragging
my car behind. It was insane.
My plans are to go into industry. Big Pharma. I would
prefer to go to a big pharmaceutical company rather
than a start-up.
I came in April of last year. This is my second postdoc.
I did one for three and a half years in Denmark. I met
[Associate Professor] Jeff [Harper] in Copenhagen when
he came to visit. He was the attraction for me, rather
than Scripps. Eventually, I will go back to Europe,
probably Denmark, to do research and teaching at a university.
The last thing I remember about Denmark is the rain.
It was a rainy day. We got our heat shock in Texas-Houston-where
we changed planes in the middle of the night.
My impression of the area of science here in the United
States: everything is going pretty much into proteomics
and high-throughput screening. That has been the most
striking difference to me from Europe, where we are
still used to working on particular problems on single
proteins. Here everything is designed to immediately
attack hundreds of proteins.
I completed my Ph.D. graduate work at Loma
Linda University in the Center for Perinatal Biology,
which focused on the fetal coronary vasculature. After
finishing up a summer project there, I came to The Scripps
Research Institute for my postdoctoral fellowship.
Two important factors that influenced my decision
to choose Scripps were: 1) TSRI had a vascular biology
department with prominent scientists and 2) my family
and fiancée are here in San Diego. I looked on
the web and saw the different descriptions of the science
going on here at Scripps, and I knew I wanted to come
here. I was particularly interested in the research
in [Associate Professor] Lindsey Miles lab, which
focused on the regulation of plasminogen, a key component
of the fibrinolytic system. I've been at Scripps for
18 months and I enjoy working with my PI and mentor,
Dr. Lindsey Miles.
I arrived last June. I was finishing my Ph.D. in Zurich
at ETH. I was in the biology field as well. Phage display
technology. Before that I was at the University of Zurich,
where I finished my M.D. My childhood was in the Swiss
countryside, in Lucerne.
People are more friendly here than in the bigger towns
in Switzerland. Not the countrysidepeople are
friendly there as well. Here people say, "Hello" wherever
you go. And they probably dont even want to know
how you are doing, but they ask you at least. I like
it very much here. Americans are more prudish than European
people, but something like Mardi Gras you would never
see in Europe. All the flashing.
The last thing I remember about Switzerland? I was
in such a hurry. I should have told my boss my job here
started one month earlier. I had to pack everything.
We brought everything we didnt take here to the
grandparents. I got married one month before we left.
I had to write my thesis and defend it that month. And
I baptized my son two weeks before we left.
I wanted to go to a good protein engineering group.
I had seen the papers of Dr. [Carlos] Barbas, and they
looked pretty good. So I wrote Carlos about a position.
There was some interest, and he wrote me back, "Just
apply." Everything went very easily and very fast.
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