Torbett Laboratory

The Torbett Laboratory has three research areas: Evolution of HIV-1 inhibitor resistance and fitness; Hematopoietic stem and T cell gene delivery strategies to block HIV-1entry and limit infection; and The regulation of normal and abnormal myeloid development and function by the ets transcription factor PU.1 (spi). Please check the Research page for more information on our research program.

Recent Publication (Blood): Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes 

Press Release from Scripps Research: When added to gene therapy, plant-based compound may enable faster, more effective treatments

Projects

Hexokinases - Their Role in Differentiation, Metabolism, and Autophagy

CD46 Null Packaging Cell Line Improves Measles Lentiviral Vector Production and Gene Delivery to Hematopoietic Stem and Progenitor Cells

A Small Molecule Approach for Investigating Lentiviral Vector Transduction Resistance in Hematopoietic Stem Cells

Regulation of HIV by the Host Ubiquitin-Proteasome System

Identification and Characterization of Host Factors Involved in Gag Assembly and Trafficking

The Role of PU.1 in Alternative Splicing of the Anti-Apoptotic cFLIP

Department of Immunology and Microbiology

The Scripps Research Institute

Director, Molecular Basis of Viral Pathogenesis Training Program

Director, CFAR Protein Expression and Proteomics (PEP) Core

Co-Director, HIV Interaction and Viral Evolution (HIVE) Center

Co-Director, UCSD Center for AIDS Research (CFAR)

10550 North Torrey Pines Road, IMM-115
La Jolla, CA 92037
Phone: (858) 784-9123
FAX: (858) 784-7714

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