Torbett Laboratory

The Torbett Laboratory has three research areas: Evolution of HIV-1 inhibitor resistance and fitness; Hematopoietic stem and T cell gene delivery strategies to block HIV-1entry and limit infection; and The regulation of normal and abnormal myeloid development and function by the ets transcription factor PU.1 (spi). Please check the Research page for more information on our research program.

 

PUBLICATIONS

Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy. Garg, D., Torbett, B.E. Virus Res. 2014 Jul 12. pii: S0168-1702(14)00270-6. PMID: 25026536 PMCID:PMC4252855
Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease. Flynn WF, Chang MW, Tan Z, Oliveira G, Yuan J, Okulicz JF, *Torbett BE, *Levy RM. PLoS Comput Biol. 2015 Apr 20;11(4):e1004249. doi: 10.1371/journal.pcbi.1004249. eCollection 2015 Apr. PMID: 25894830 Free PMC Article Related citations Select item 25788875 PMCID: PMC4404092
Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells. Wang CX, Sather BD, Wang X, Adair J, Khan I, Singh S, Lang S, Adams A, Curinga G, Kiem HP, Miao CH, Rawlings DJ, Torbett BE. Blood. 2014 Aug 7;124(6):913-23. Epub 2014 Jun 9. PMID: 24914132 PMCID:PMC4126331
Rapid deep sequencing of patient-derived HIV with ion semiconductor technology. Chang MW, Oliveira G, Yuan J, Okulicz JF, Levy S, Torbett BE. J Virol Methods. 2013 Apr;189(1):232-4. Epub 2013 Feb 4. PMID: 23384677  PMCID:PMC3608812
Role of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cells. Wang, CX. Torbett, BE. Curr Opin Hematol. 2015 Jul;22(4):302-308. PMID:26049750

 

betorbet

Department of Immunology and Microbiology

The Scripps Research Institute

Director, Molecular Basis of Viral Pathogenesis Training Program

Director, CFAR Protein Expression and Proteomics (PEP) Core

Co-Director, HIV Interaction and Viral Evolution (HIVE) Center

Co-Director, UCSD Center for AIDS Research (CFAR)

 


10550 North Torrey Pines Road, IMM-115
La Jolla, CA 92037
Phone: (858) 784-9123
FAX: (858) 784-7714