Core Microscopy Facility

La Jolla, California Campus

The Core Microscopy Facility at Scripps Research provides researchers with equipment and expertise required for multi-dimensional imaging of cells and tissues at high resolution and to perform quantitative image analysis. Resources include widefield, confocal, multi-photon, TIRF, super-resolution and electron microscopy, as well as equipment for live cell imaging and image analysis. Services include sample preparation, imaging, molecular localization, and image analysis. In addition to providing access to advanced instrumentation, this facility, staffed by experts, is a source of instruction and training and constitutes a major educational resource. The Facility staff provides training, technical support, sample preparation, imaging assistance, collaboration and consultation.

The Core Microscopy Facility operates on a fee-for-services basis.

Electron Microscopy

Light Microscope

Online calendars are available to reserve time on each individual instrument and qualified independent users can log on from their own labs to make their own appointments. All of the  7 computers operating the confocal and laser capture microscope(s), imaging workstations as well as the CCD camera for the CM-100 electron microscope are on-line for downloading image data directly to lab computers. 

Confocal Zeiss 710 (conf 7) 
Confocal Zeiss 780 (conf 9) 
Confocal Zeiss 880 Airyscan (conf 11) 
BZ-X700 Keyence Scanner (conf10) 
Workstation - conf 5 
Workstation - conf 6 
Workstation - conf 8 
Laser Capture 
S-4800 (SEM)
Nikon Spinning Disk Confocal 
Nikon TIRF/STORM Super resolution Confocal 
Leica SP5 Multiphoton Confocal 
Nikon STORM Workstation  

Laser Scanning Confocal: LSM780, LSM710 and LSM880 hourly rate for usage: For Scripps Research trained user, $43/hr. Contact  schenderson@scripps.edu for training.

Laser Capture Microdissection: LCM hourly rate for usage: For Scripps Research trained user, $30/hr. Contact  wkiosses@scripps.edu for training.

Bz-X700 Fluorescence Microscope: Bz-X700 hourly rate: For Scripps Research trained user, $10/hr 

  • Peak hours (9 a.m.-5 p.m., Monday-Friday): $5/hr
  • Non-peak hours: Contact  schenderson@scripps.edu for training.

Image analysis: Workstation hourly rate for usage: For Scripps Research trained user, $10/hr. Contact wkiosses@scripps.edu for training.

Nikon Spinning Disk Confocal: Hourly rate for usage: For Scripps Research trained user, $10/hr Monday-Friday, 9 a.m.-5 p.m.; $8/hr 6-9 a.m., 5-9 p.m. and during weekends. $50 flat rate overnight. Contact kpestonj@scripps.edu for training. 

Nikon Total Internal Reflection Fluorescence: Hourly rate for usage: For Scripps Research trained user, $25/hr Monday-Friday, 9 a.m.-5 p.m.; $12/hr 6-9 p.m. and during weekends. $50 flat rate overnight. Contact kpestonj@scripps.edu for training.

Nikon Workstation (Room MBB34E): Hourly rate for usage: For Scripps Research trained user, $5/hr. Contact kpestonj@scripps.edu for training.

Leica TCS SP5 Two-Photon Microscope: Hourly rate for usage: For Scripps Research trained user,  $12/hr Monday-Friday, 9 a.m.-5 p.m.; $8/hr 6-9 a.m., 5-9 p.m. and during weekends. $50 flat rate overnight. Contact kpestonj@scripps.edu for training.

Contacts