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Kyungmoo Yea, Ph.D.

Assistant Professor of CMB
Department of Chemistry
California Campus
Scripps VIVO Scientific Profile
kyungmoo@scripps.edu
(858) 784-8265

Education

Ph.D. (Life Science), Pohang University of Science and Technology 2008
M.S. (Life Science), Pohang University of Science and Technology 2004
B.S. (Life Science), Korea University 2000

Professional Experience

2015-2017 Assistant Professor of CMB, Cell and Molecular Biology (CMB), The Scripps Research Institute
2013-2015 Professional Scientific Collaborator, Cell and Molecular Biology (CMB), The Scripps Research Institute
2013-2015 Research Associate Professor, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University
2012-2013 Senior Scientist, Scripps Korea Antibody Institute
2009-2012 Postdoctoral Associate, Sanford Burnham Prebys Medical Discovery Institute
2008-2009 Postdoctoral Associate, Signaling Proteome Lab, Pohang University of Science and Technology

Awards & Professional Activities

2014 Young Scientist Award, SLAS (Society for Laboratory Automation and Screening)

Selected References

All Publications

Bucher, F., Zhang, D., Aguilar, E., Sakimoto, S., Diaz-Aguilar, S., Rosenfeld, M., Zha, Z., Zhang, H., Friedlander, M. & Yea, K. Antibody-mediated inhibition of Tspan12 ameliorates vasoproliferative retinopathy through suppression of β-catenin signaling. (2017). Circulation, 136(2), 180-195.

Zha, Z., Bucher, F., Nejatfard, A., Zheng, T., Zhang, H., Yea, K. & Lerner, R. A. Interferon-γ is a master checkpoint regulator of cytokine-induced differentiation. (2017). Proceedings of the National Academy of Sciences of the United States of America, 114(33), E6867-E6874. PMCID: PMC5565454.

Yea, K., Zhang, H. & Lerner, R. A. Activating pleiotropic receptors to kill cancer cells. (2016). Cell Cycle, 15(2), 158-159. PMCID: PMC4825822.

Zhang, H., Du, M., Xie, J., Liu, X., Sun, J., Wang, W., Xin, X., Possani, L. D., Yea, K. & Lerner, R. A. Autocrine-based selection of drugs that target ion channels from combinatorial venom peptide libraries. (2016). Angewandte Chemie-International Edition, 55(32), 9306-9310.

Lerner, R. A., Grover, R. K., Zhang, H., Xie, J., Han, K. H., Peng, Y. & Yea, K. Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates. (2015). Quarterly Reviews of Biophysics, 48(4), 389-394.

Song, P., Kwon, Y., Yea, K., Moon, H. Y., Yoon, J. H., Ghim, J., Hyun, H., Kim, D., Koh, A., Berggren, P. O., Suh, P. G., Ryu, S. H. Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase. (2015). Cellular Signalling, 27(9), 1873-1881.

Yea, K., Xie, J., Zhang, H., Zhang, W. & Lerner, R. A. Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic. (2015). Current Opinion in Chemical Biology, 26, 1.

Kim, D., Kim, J., Yoon, J. H., Ghim, J., Yea, K., Song, P., Park, S., Lee, A., Hong, C. P., Jang, M. S., Kwon, Y., Park, S., et al. CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice. (2014). Diabetologia, 57(7), 1456-1465.

Yea, K., Zhang, H., Moldt, B., He, L., Zhu, J. & Lerner, R. A. Prevention of cell death by antibodies selected from intracellular combinatorial libraries. (2014). Chemistry & Biology, 21(2), 274-283.

Xie, J., Zhang, H., Yea, K. & Lerner, R. A. Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells. (2013). Proceedings of the National Academy of Sciences of the United States of America, 110(20), 8099-8104. PMCID: PMC3657831.