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Annette Von Drygalski, M.D.

Associate Professor Adjunct
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
(858) 784-8236

Professional Experience

2009-2017 Associate Professor Adjunct, Molecular and Experimental Medicine (MEM), The Scripps Research Institute

Selected References

All Publications

Huang, W. T., Cang, W. C., Derry, K. L., Lane, J. R. & von Drygalski, A. Four-factor prothrombin complex concentrate for coagulopathy reversal in patients with liver disease. (2017). Clinical and Applied Thrombosis-Hemostasis, 23(8), 1028-1035.

Barnes, R. F. W., Cramer, T. J., Hughes, T. H. & von Drygalski, A. The hypertension of hemophilia is associated with vascular remodeling in the joint. (2017). Microcirculation, 24.

Wyseure, T., Mosnier, L. O. & von Drygalski, A. Advances and challenges in hemophilic arthropathy. (2016). Seminars in Hematology, 53(1), 10-19. PMCID: PMC5034876.

Cramer, T. J., Anderson, K., Navaz, K., Brown, J. M., Mosnier, L. O. & von Drygalski, A. Heterozygous congenital Factor VII deficiency with the 9729de14 mutation, associated with severe spontaneous intracranial bleeding in an adolescent male. (2016). Blood Cells Molecules and Diseases, 57, 8. PMCID: PMC4874642.

Bhat, V., von Drygalski, A., Gale, A. J., Griffin, J. H. & Mosnier, L. O. Improved coagulation and haemostasis in haemophilia with inhibitors by combinations of superFactor Va and Factor VIIa. (2016). Thrombosis and Haemostasis, 115(3), 551-561. PMCID: PMC4775351.

Gale, A. J., Bhat, V., Pellequer, J. L., Griffin, J. H., Mosnier, L. O. & Von Drygalski, A. Safety, stability and pharmacokinetic properties of (super)Factor Va, a novel engineered coagulation Factor V for treatment of severe bleeding. (2016). Pharmaceutical Research, 33(6), 1517-1526. PMCID: PMC4854778.

Bhat, V., Olmer, M., Joshi, S., Durden, D. L., Cramer, T. J., Barnes, R. F. W., Ball, S. T., Hughes, T. H., Silva, M., Luck, J. V., Moore, R. E., Mosnier, L. O., et al. Vascular remodeling underlies rebleeding in hemophilic arthropathy. (2015). American Journal of Hematology, 90(11), 1027-1035. PMCID: PMC4618067.

von Drygalski, A., Bhat, V., Gale, A. J., Burnier, L., Cramer, T. J., Griffin, J. H. & Mosnier, L. O. An engineered Factor Va prevents bleeding induced by anticoagulant wt activated protein C. (2014). PLoS One, 9, e104304. PMCID: PMC4134195.

von Drygalski, A., Cramer, T. J., Bhat, V., Griffin, J. H., Gale, A. J. & Mosnier, L. O. Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant. (2014). Journal of Thrombosis and Haemostasis, 12(3), 363-372. PMCID: PMC4161283.

Macauley, M. S., Pfrengle, F., Rademacher, C., Nycholat, C. M., Gale, A. J., von Drygalski, A. & Paulson, J. C. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis. (2013). Journal of Clinical Investigation, 123(7), 3074-3083. PMCID: PMC3706185.