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Vladimir Kravchenko, Ph.D.

Assistant Professor of Immunology
Department of Immunology and Microbiology
California Campus
Scripps VIVO Scientific Profile
(858) 784-9170


Ph.D. (Molecular Biology), Russian Academy of Sciences 1982

Professional Experience

1991-2017 Assistant Professor of Immunology, Immunology and Microbial Science (IMS), The Scripps Research Institute

Selected References

All Publications

Shi, H., Wang, Y., Li, X., Zhan, X., Tang, M., Fina, M., Su, L., Pratt, D., Bu, C. H., Hildebrand, S., Lyon, S., Scott, L., et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. (2016). Nature Immunology, 17(3), 250-258. PMCID: PMC4862588.

Jacob, N. T., Lockner, J. W., Kravchenko, V. V. & Janda, K. D. Pharmacophore reassignment for induction of the immunosurveillance cytokine TRAIL. (2014). Angewandte Chemie-International Edition, 53(26), 6628-6631.

Kravchenko, V. V. & Kaufmann, G. F. Bacterial inhibition of inflammatory responses via TLR-independent mechanisms. (2013). Cellular Microbiology, 15(4), 527-536.

Kravchenko, V., Garner, A. L., Mathison, J., Seit-Nebi, A., Yu, J., Gileva, I. P., Ulevitch, R. & Janda, K. D. Facilitating cytokine-mediated cancer cell death by proteobacterial N-acylhomoserine lactones. (2013). ACS Chemical Biology, 1117-1120. PMCID: PMC3755046.

Garner, A. L., Yu, J., Struss, A. K., Kaufmann, G. F., Kravchenko, V. V. & Janda, K. D. Immunomodulation and the quorum sensing molecule 3-oxo-C-12-homoserine lactone: The importance of chemical scaffolding for probe development. (2013). Chemical Communications, 49(15), 1515-1517. PMCID: PMC3566768.

Dubinsky, L., Delago, A., Amara, N., Krief, P., Rayo, J., Zor, T., Kravchenko, V. V. & Meijler, M. M. Species selective diazirine positioning in tag-free photoactive quorum sensing probes. (2013). Chemical Communications, 49(52), 5826-5828. PMCID: PMC3723129.

Glucksam-Galnoy, Y., Sananes, R., Silberstein, N., Krief, P., Kravchenko, V. V., Meijler, M. M. & Zor, T. The bacterial quorum-sensing signal molecule N-3-oxo-dodecanoyl-L-homoserine lactone reciprocally modulates pro- and anti-inflammatory cytokines in activated macrophages. (2013). Journal of Immunology, 191(1), 337-344. PMCID: PMC3691282.

Kravchenko, V. V., Gloeckner, C., Stowe, G. N., Kang, Y. J., Tobias, P. S., Mathison, J. C., Ulevitch, R. J., Kaufmann, G. F. & Janda, K. D. The use of small molecule probes to study spatially separated stimulus-induced signaling pathways. (2012). Bioorganic & Medicinal Chemistry Letters, 22(5), 2043-2045. PMCID: PMC3288742.

Kravchenko, V. V., Ulevitch, R. J. & Kaufmann, G. F. Modulation of mammalian cell processes by bacterial quorum sensing molecules. (2011). Methods in Molecular Biology, 692, 133.

Garner, A. L., Yu, J., Struss, A. K., Lowery, C. A., Zhu, J., Kim, S. K., Park, J., Mayorov, A. V., Kaufmann, G. F., Kravchenko, V. V. & Janda, K. D. Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: Unanticipated effects on mammalian cell activation. (2011). Bioorganic & Medicinal Chemistry Letters, 21(9), 2702-2705. PMCID: PMC3081916.