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Darlene Elias, M.D.

Professor of Molecular Medicine
Department of Molecular Medicine
California Campus
Scripps VIVO Scientific Profile
delias@scripps.edu
(858) 784-8220

Professional Experience

2017-2017 Assistant Professor Adjunct, Molecular Medicine, The Scripps Research Institute
2006-2017 Assistant Professor Adjunct, Molecular and Experimental Medicine (MEM), The Scripps Research Institute

Selected References

All Publications

Deguchi, H., Banerjee, Y., Elias, D. J. & Griffin, J. H. Elevated CETP lipid transfer activity is associated with the risk of venous thromboembolism. (2016). Journal of Atherosclerosis and Thrombosis, 23(10), 1159-1167. PMCID: PMC5064881.

Deguchi, H., Banerjee, Y., Trauger, S., Siuzdak, G., Kalisiak, E., Fernandez, J. A., Hoang, L., Tran, M., Yegneswaran, S., Elias, D. J. & Griffin, J. H. Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data. (2015). Blood, 126(13), 1595-1600. PMCID: PMC4582336.

Ivanisevic, J., Elias, D., Deguchi, H., Averell, P. M., Kurczy, M., Johnson, C. H., Tautenhahn, R., Zhu, Z., Watrous, J., Jain, M., Griffin, J., Patti, G. J., et al. Arteriovenous blood metabolomics: a readout of intra-tissue metabostasis. (2015). Scientific Reports, 5, 12757. PMCID: PMC4525490.

Deguchi, H., Elias, D. J. & Griffin, J. H. Gain in translation: heme oxygenase-1 induced by activated protein C promotes thrombus resolution. (2014). Journal of Thrombosis and Haemostasis, 12(1), 90-92. PMCID: PMC4062081.

Deguchi, H., Elias, D. J., Trauger, S., Zhang, H. M., Kalisiak, E., Siuzdak, G. & Griffin, J. H. Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids. (2014). British Journal of Haematology, 165(3), 409-412. PMCID: PMC3984601.

Deguchi, H., Elias, D. J., Navarro, S., Espana, F. & Griffin, J. H. Elevated serum amyloid A is associated with venous thromboembolism. (2013). Thrombosis and Haemostasis, 109(2), 358-359. PMCID: PMC3579663.

von Drygalski, A., Kolaitis, N. A., Bettencourt, R., Bergstrom, J., Kruse-Jarres, R., Quon, D. V., Wassel, C., Li, M. C., Waalen, J., Elias, D. J., Mosnier, L. O., Allison, M. Prevalence and risk factors for hypertension in hemophilia. (2013). Hypertension, 62(1), 209-215.

Gale, A. J., Elias, D. J., Averell, P. M., Teirstein, P. S., Buck, M., Brown, S. D., Polonskaya, Z., Udit, A. K. & Finn, M. G. Engineered virus-like nanoparticles reverse heparin anticoagulation more consistently than protamine in plasma from heparin-treated patients. (2011). Thrombosis Research, 128(4), E9-E13. PMCID: PMC3153569.

Cheung, M. C., Albers, J. J., Kennedy, H., Deguchi, H., Elias, D. J., Averell, P. M., Griffin, J. H. & Marcovina, S. M. Association of Apo(a)isoform size with dyslipoproteinemia in male venous thrombosis patients. (2010). Clinica Chimica Acta, 411(17-18), 1279-1283. PMCID: PMC3427714.

Pecheniuk, N. M., Elias, D. J., Xu, X. & Griffin, J. H. Failure to validate association of gene polymorphisms in EPCR, PAR-1, FSAP and protein S Tokushima with venous thromboembolism among Californians of European ancestry. (2008). Thrombosis and Haemostasis, 99(2), 453-455.